IGDB.NSCLC Chromosome View

Chromosome 9
9p24 9p23 9p22 9p21 9p13 9p12 9p11 9q11 9q12 9q13 9q21 9q22 9q31 9q32 9q33 9q34         (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.
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    Lung Cancer Genes with Experimental Evidence         (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: up-regulation / green : down-regulation / gray : mutation)

CDKN2A, down, 25/101(25%) CDKN2A, up, 57/106(54%) CDKN2A, 16.96%, 145/855 CDKN2B, 0.53%, 1/189 TEK, 0.99%, 2/202

(Click the gene to hyperlink to gene view.)    

    Gene Expression Microarray Data         (help)
            ( red: up-regulation / green : down-regulation)

         Adenocarcinoma          Squamous Cell Carcinoma
        HG_U95 (Meyerson, GSE2514)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      MTAP,FC=0.34,p=0.122490424 CDKN2A,FC=0.91,p=0.003066409 CDKN2B,FC=-0.01,p=0.922459296 CDKN2B,FC=-0.55,p=0.002133493 ELAVL2,FC=0.16,p=0.498993476 ELAVL2,FC=0.45,p=0.001457352 PLAA,FC=-0.30,p=0.251669156 TEK,FC=-1.67,p=5.97e-17 TEK,FC=-3.28,p=1.59e-36

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      MTAP,FC=0.11,p=0.723535217 CDKN2A,FC=1.74,p=0.000358558 CDKN2B,FC=0.09,p=0.675300961 CDKN2B,FC=-0.79,p=0.009620698 ELAVL2,FC=0.27,p=0.444099714 ELAVL2,FC=0.53,p=0.006780505 PLAA,FC=0.04,p=0.913272686 TEK,FC=-2.49,p=9.7e-17 TEK,FC=-3.93,p=7.69e-23


        HG_U133A (GSE7670, GSE17475, DCLungStudy, GSE4573, GSE10072)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      MTAP,FC=0.22,p=0.028424319 MTAP,FC=1.03,p=3.25e-09 MTAP,FC=-0.37,p=1.92e-10 MTAP,FC=0.75,p=1.97e-05 C9orf53,FC=-0.55,p=4.47e-08 CDKN2A,FC=1.20,p=2.22e-16 CDKN2A,FC=0.13,p=0.240013036 CDKN2A,FC=0.76,p=6.43e-08 CDKN2B,FC=0.60,p=0.000128255 ELAVL2,FC=-0.17,p=0.249683538 C9orf82,FC=0.39,p=1.45e-08 PLAA,FC=-0.11,p=0.260132573 PLAA,FC=0.06,p=0.394902837 IFT74,FC=-0.39,p=0.047847696 IFT74,FC=-0.75,p=6.76e-07 LRRC19,FC=-0.48,p=0.000651646 TEK,FC=-0.86,p=2.76e-14 TEK,FC=-2.70,p=1.33e-106 MOBKL2B,FC=-0.30,p=9.57e-06

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      MTAP,FC=4.78,p=4.85e-75 MTAP,FC=0.97,p=2.57e-10 MTAP,FC=-1.38,p=4.72e-58 MTAP,FC=4.30,p=1.24e-93 C9orf53,FC=0.22,p=0.142427995 CDKN2A,FC=3.18,p=1.05e-58 CDKN2A,FC=4.55,p=2.54e-105 CDKN2A,FC=2.13,p=6.98e-59 CDKN2B,FC=4.16,p=5.91e-72 ELAVL2,FC=0.77,p=9.6e-10 C9orf82,FC=-0.97,p=2.72e-14 PLAA,FC=5.26,p=1.15e-117 PLAA,FC=2.46,p=4.34e-90 IFT74,FC=4.18,p=2.27e-92 IFT74,FC=3.06,p=1.11e-68 LRRC19,FC=2.93,p=5.6e-63 TEK,FC=-1.44,p=1.43e-21 TEK,FC=-5.96,p=1.84e-101 MOBKL2B,FC=-0.21,p=0.011287561


        HG_U133_Plus2 (GSE3141, GSE10245, GSE10445, GSE12667, GSE10799, GSE16538, GSE7307, GSE3526)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      MTAP,FC=0.21,p=0.271785004 MTAP,FC=0.69,p=5.59e-07 MTAP,FC=0.73,p=0.001495333 MTAP,FC=-0.05,p=0.740211553 MTAP,FC=0.10,p=0.443123691 C9orf53,FC=-0.09,p=0.634534955 CDKN2A,FC=1.42,p=1.83e-09 CDKN2A,FC=0.10,p=0.475916419 CDKN2A,FC=1.46,p=3.99e-14 CDKN2BAS,FC=-0.18,p=0.320658794 CDKN2B,FC=-0.00,p=0.985892164 CDKN2B,FC=-1.56,p=6.08e-19 DMRTA1,FC=0.07,p=0.585900889 ELAVL2,FC=0.48,p=0.018555985 ELAVL2,FC=0.74,p=0.00027072 TUSC1,FC=-0.50,p=4.27e-06 C9orf82,FC=-0.17,p=0.177410214 C9orf82,FC=0.17,p=0.064222594 PLAA,FC=0.01,p=0.889230601 PLAA,FC=-0.60,p=3e-05 PLAA,FC=-0.58,p=1.13e-08 IFT74,FC=-0.27,p=0.015003319 IFT74,FC=-0.71,p=8.24e-07 LRRC19,FC=-0.62,p=0.00598988 TEK,FC=-2.47,p=1.77e-53 TEK,FC=0.64,p=0.00587704 C9orf11,FC=-0.44,p=0.076619653 C9orf11,FC=0.05,p=0.771804339 C9orf11,FC=-0.15,p=0.398773674 MOBKL2B,FC=-0.75,p=2.4e-10 MOBKL2B,FC=-0.93,p=1.63e-15 MOBKL2B,FC=-0.36,p=0.001809571 MOBKL2B,FC=-0.41,p=0.000114945 IFNK,FC=0.02,p=0.912211582 C9orf72,FC=-1.16,p=1.14e-08 C9orf72,FC=-1.58,p=1.62e-20 C9orf72,FC=-0.63,p=9.67e-16 LINGO2,FC=0.91,p=2.58e-08 HCG18,FC=0.09,p=0.28557733

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      MTAP,FC=0.29,p=0.153626202 MTAP,FC=1.32,p=5.87e-12 MTAP,FC=0.42,p=0.122386337 MTAP,FC=-0.21,p=0.326203662 MTAP,FC=-0.11,p=0.579790842 C9orf53,FC=-0.41,p=0.044630394 CDKN2A,FC=1.72,p=2.78e-06 CDKN2A,FC=0.57,p=0.000472698 CDKN2A,FC=2.37,p=3.68e-22 CDKN2BAS,FC=-0.21,p=0.31678238 CDKN2B,FC=0.39,p=0.121300302 CDKN2B,FC=-1.56,p=2.36e-10 DMRTA1,FC=0.24,p=0.072786333 ELAVL2,FC=0.12,p=0.633095343 ELAVL2,FC=0.30,p=0.171068221 TUSC1,FC=-0.28,p=0.009913318 C9orf82,FC=-0.78,p=2.7e-07 C9orf82,FC=-0.28,p=0.013239217 PLAA,FC=-0.19,p=0.060092486 PLAA,FC=-0.80,p=1.75e-07 PLAA,FC=-0.78,p=3.03e-14 IFT74,FC=-0.86,p=4.19e-07 IFT74,FC=-1.32,p=9.68e-10 LRRC19,FC=-0.64,p=0.003639723 TEK,FC=-3.32,p=4.55e-31 TEK,FC=1.39,p=1.54e-06 C9orf11,FC=-0.94,p=0.001322172 C9orf11,FC=0.32,p=0.086982387 C9orf11,FC=-0.26,p=0.157533082 MOBKL2B,FC=-0.86,p=1.38e-11 MOBKL2B,FC=-1.22,p=7.23e-22 MOBKL2B,FC=-0.00,p=0.991245887 MOBKL2B,FC=-0.12,p=0.267540105 IFNK,FC=-0.31,p=0.252926668 C9orf72,FC=-1.21,p=3.45e-07 C9orf72,FC=-1.60,p=2.31e-13 C9orf72,FC=-0.53,p=3.14e-06 LINGO2,FC=1.41,p=3.45e-16 HCG18,FC=-0.31,p=0.000633417


        Stanford (GSE3398)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      CDKN2A,FC=0.73,p=0.175486161 TEK,FC=-2.08,p=4.84e-09

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      CDKN2A,FC=-0.33,p=0.358907953 TEK,FC=-2.45,p=5.37e-08


        Agilent_HS_21.6K (GSE11969)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      MTAP,FC=0.03,p=0.598355909 CDKN2A,FC=-0.02,p=0.776640649 CDKN2A,FC=0.29,p=0.001986532 CDKN2B,FC=-0.40,p=0.035328341 CDKN2B,FC=-0.15,p=0.010049209 DMRTA1,FC=-0.05,p=0.508134671 ELAVL2,FC=0.07,p=0.005379548 C9orf82,FC=-0.01,p=0.902287448 PLAA,FC=0.01,p=0.805120328 LRRC19,FC=-0.04,p=0.669046831 TEK,FC=0.07,p=0.44107866 MOBKL2B,FC=0.00,p=0.938296132 MOBKL2B,FC=-0.02,p=0.328465259 IFNK,FC=-0.00,p=0.965134111 C9orf72,FC=-0.09,p=0.064639913 C9orf72,FC=-0.02,p=0.461655341

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      MTAP,FC=0.02,p=0.720292962 CDKN2A,FC=0.00,p=0.950460067 CDKN2A,FC=0.35,p=0.000311672 CDKN2B,FC=-0.34,p=0.117352975 CDKN2B,FC=-0.09,p=0.324697735 DMRTA1,FC=-0.09,p=0.252342588 ELAVL2,FC=0.05,p=0.07360296 C9orf82,FC=-0.01,p=0.672124722 PLAA,FC=0.01,p=0.647087375 LRRC19,FC=0.01,p=0.949182857 TEK,FC=0.03,p=0.469880768 MOBKL2B,FC=-0.03,p=0.488032405 MOBKL2B,FC=-0.03,p=0.082460898 IFNK,FC=-0.00,p=0.998905457 C9orf72,FC=-0.07,p=0.351651993 C9orf72,FC=-0.02,p=0.357603553


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    Copy Number Alteration Data        (help)
            ( red: amplification / green : deletion)

         Adenocarcinoma          Squamous Cell Carcinoma
        Meyerson Adenocarcinoma (SNP)      Save as a PNG file. Save as a PDF file. Save as a PS file.
      

        GSE17958 Squamous Cell Carcinoma (SNP)      Save as a PNG file. Save as a PDF file. Save as a PS file.
      

        GSE12280_SGOL (SCC / aCGH)      Save as a PNG file. Save as a PDF file. Save as a PS file.
      

      

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    miRNA Expression Data        (help)
            ( red: up-regulation / green : down-regulation)

         Adenocarcinoma          Squamous Cell Carcinoma
        GSE15201
        Adenocarcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picturehsa-miR-31,Mean=0.12

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picturehsa-miR-31,Mean=0.39

        GSE18692
        Adenocarcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picturehsa-mir-31,Mean=0.81

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picturehsa-mir-31,Mean=2.11

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    Paired (U133A/aCGH) AD Sample Data        (help) (PubMed)       Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: amplification / green : deletion)

MTAP,FC=0.45,p=0.000174684 MTAP,FC=1.63,p=7.74e-15 MTAP,FC=-1.08,p=4.27e-20 MTAP,FC=1.22,p=2.16e-09 C9orf53,FC=-1.19,p=6.13e-19 CDKN2A,FC=1.04,p=4.88e-14 CDKN2A,FC=0.14,p=0.285266025 CDKN2A,FC=0.74,p=9.29e-07 CDKN2B,FC=1.16,p=4.02e-09 ELAVL2,FC=-0.29,p=0.086288468 C9orf82,FC=0.44,p=1.67e-08 PLAA,FC=0.20,p=0.064111588 PLAA,FC=0.12,p=0.14999433 IFT74,FC=0.54,p=0.006285864 IFT74,FC=-0.09,p=0.608106545 LRRC19,FC=-1.06,p=1.8e-09 TEK,FC=-0.85,p=1.56e-10 TEK,FC=-2.57,p=4.36e-66 MOBKL2B,FC=-0.34,p=1.35e-06

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    Array CGH Data        (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: amplification / green : deletion)

RP11-495L19, 4/50, 0.08 RP11-495L19, 12/50, 0.24 RP11-33K8, 0/50, 0 RP11-33K8, 12/50, 0.24 RP11-468C2, 1/50, 0.02 RP11-468C2, 11/50, 0.22 RP11-33G16, 1/50, 0.02 RP11-33G16, 16/50, 0.32 RP11-5P15, 2/50, 0.04 RP11-5P15, 11/50, 0.22 RP11-27J8, 3/50, 0.06 RP11-27J8, 15/50, 0.3 RP11-20P5, 3/50, 0.06 RP11-20P5, 13/50, 0.26 RP11-264J11, 5/50, 0.1 RP11-264J11, 17/50, 0.34 RP11-383F6, 3/50, 0.06 RP11-383F6, 21/50, 0.42 RP11-48L13, 3/50, 0.06 RP11-48L13, 10/50, 0.2

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    CGH Minimal Deletion Region Data        (help)      Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: amplification / green : deletion)

PMID=

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    LOH Frequency Data        (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.

Our unpublished data D9S171, 5/40, 13% Our unpublished data D9S169, 23/27, 85% Our unpublished data D9S1853, 11/36, 31% D9S171, 11/14, 79% PMID=10987304 D9S161, 12/16, 75% PMID=11980668 D9S251, 16/33, 48% D9S942, 7/25, 28% PMID=15900585 D9S942, 8/25, 32%

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