IGDB.NSCLC Chromosome View

Chromosome 9
9p24 9p23 9p22 9p21 9p13 9p12 9p11 9q11 9q12 9q13 9q21 9q22 9q31 9q32 9q33 9q34         (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.
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    Lung Cancer Genes with Experimental Evidence         (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: up-regulation / green : down-regulation / gray : mutation)

CA9, up, 142/175(82%) TESK1, 0.50%, 1/202 MELK, 7.14%, 1/14

(Click the gene to hyperlink to gene view.)    

    Gene Expression Microarray Data         (help)
            ( red: up-regulation / green : down-regulation)

         Adenocarcinoma          Squamous Cell Carcinoma
        HG_U95 (Meyerson, GSE2514)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      UNC13B,FC=-0.51,p=0.001464889 RUSC2,FC=-0.06,p=0.563343488 TESK1,FC=-0.10,p=0.180817536 CD72,FC=0.23,p=0.267116401 SIT1,FC=0.29,p=0.005355467 CA9,FC=0.70,p=0.006267255 TPM2,FC=-0.62,p=0.000253698 TPM2,FC=-0.27,p=0.032718564 TPM2,FC=0.90,p=7.23e-05 TLN1,FC=-0.53,p=6.73e-10 CREB3,FC=0.12,p=0.151154336 NPR2,FC=-0.54,p=0.000857466 SPAG8,FC=-0.01,p=0.884868353 RECK,FC=-0.91,p=3.66e-05 RECK,FC=0.10,p=0.575503433 RECK,FC=-2.10,p=9.29e-16 CCIN,FC=-0.26,p=0.124876766 CLTA,FC=-0.12,p=0.126992444 GNE,FC=-0.13,p=0.118375949 MELK,FC=1.03,p=8.33e-08 PAX5,FC=0.13,p=0.352798691

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      UNC13B,FC=-1.28,p=1.32e-14 RUSC2,FC=-0.01,p=0.897357233 TESK1,FC=-0.08,p=0.494287845 CD72,FC=0.43,p=0.116885314 SIT1,FC=0.31,p=0.009867614 CA9,FC=2.25,p=1.62e-10 TPM2,FC=-0.51,p=0.003551202 TPM2,FC=-0.34,p=0.012791145 TPM2,FC=1.12,p=0.000426835 TLN1,FC=-0.70,p=2.39e-08 CREB3,FC=-0.06,p=0.567097993 NPR2,FC=-0.92,p=1.23e-05 SPAG8,FC=-0.15,p=0.177993959 RECK,FC=-1.20,p=7.36e-06 RECK,FC=0.09,p=0.669130337 RECK,FC=-2.51,p=2.66e-13 CCIN,FC=0.01,p=0.974627151 CLTA,FC=0.37,p=0.001879139 GNE,FC=-0.01,p=0.887637223 MELK,FC=1.60,p=1.81e-07 PAX5,FC=0.40,p=0.094770266


        HG_U133A (GSE7670, GSE17475, DCLungStudy, GSE4573, GSE10072)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      UNC13B,FC=-0.35,p=5.81e-05 RUSC2,FC=-0.84,p=4.36e-09 TESK1,FC=-0.13,p=0.043260931 CD72,FC=0.39,p=0.021220642 SIT1,FC=-0.07,p=0.586574537 CA9,FC=0.27,p=0.047960085 TPM2,FC=-0.40,p=0.000186768 TPM2,FC=0.03,p=0.863735581 TLN1,FC=-0.40,p=8.34e-09 CREB3,FC=0.27,p=8.69e-06 NPR2,FC=-1.08,p=6.12e-14 NPR2,FC=-0.51,p=1.17e-09 SPAG8,FC=-0.11,p=0.241981347 SPAG8,FC=0.13,p=0.20663524 TMEM8B,FC=-0.28,p=9.61e-05 OR2S2,FC=-0.13,p=0.00633593 RECK,FC=-2.02,p=1.73e-52 RECK,FC=0.07,p=0.561422511 CCIN,FC=-0.09,p=0.258881688 CLTA,FC=-0.01,p=0.845258945 CLTA,FC=0.51,p=5.85e-13 CLTA,FC=0.38,p=1.03e-08 CLTA,FC=0.23,p=3.84e-05 GNE,FC=-0.07,p=0.292337891 RNF38,FC=-0.79,p=2.49e-44 MELK,FC=2.40,p=4.47e-52 PAX5,FC=0.20,p=0.094878955

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      UNC13B,FC=-0.83,p=6.7e-15 RUSC2,FC=-3.56,p=7.57e-73 TESK1,FC=-0.05,p=0.54300932 CD72,FC=-0.08,p=0.629288339 SIT1,FC=0.39,p=0.007319887 CA9,FC=-0.57,p=3.8e-13 TPM2,FC=-2.79,p=2.92e-63 TPM2,FC=4.10,p=2.71e-83 TLN1,FC=-0.08,p=0.592628729 CREB3,FC=1.66,p=5.22e-51 NPR2,FC=-2.67,p=4.1e-42 NPR2,FC=2.26,p=7.33e-43 SPAG8,FC=2.51,p=4.54e-51 SPAG8,FC=0.83,p=0.024125065 TMEM8B,FC=-2.78,p=1.7e-58 OR2S2,FC=-2.70,p=1.24e-56 RECK,FC=-0.65,p=4.53e-10 RECK,FC=2.19,p=7.38e-30 CCIN,FC=2.81,p=4.1e-101 CLTA,FC=0.22,p=0.003154568 CLTA,FC=-2.60,p=1.5e-107 CLTA,FC=-1.24,p=3.66e-13 CLTA,FC=-3.95,p=1.68e-147 GNE,FC=-0.16,p=0.158394141 RNF38,FC=-0.25,p=0.002313572 MELK,FC=4.06,p=6.25e-68 PAX5,FC=0.00,p=0.996356952


        HG_U133_Plus2 (GSE3141, GSE10245, GSE10445, GSE12667, GSE10799, GSE16538, GSE7307, GSE3526)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      UNC13B,FC=0.56,p=1.76e-06 UNC13B,FC=-0.36,p=0.042882229 LOC158381,FC=-2.03,p=1.71e-17 LOC158381,FC=-0.39,p=0.080940263 RUSC2,FC=-0.97,p=4.23e-10 FAM166B,FC=-0.36,p=0.055122298 TESK1,FC=0.05,p=0.450405402 CD72,FC=0.36,p=0.035894744 SIT1,FC=0.09,p=0.629673292 CCDC107,FC=-0.14,p=0.191569566 C9orf100,FC=1.08,p=3.56e-10 C9orf100,FC=1.60,p=2.37e-14 C9orf100,FC=1.16,p=2.82e-12 CA9,FC=1.26,p=1.88e-10 TPM2,FC=0.26,p=0.048557386 TPM2,FC=0.55,p=0.002671137 TPM2,FC=-0.59,p=6.07e-06 TLN1,FC=-0.19,p=0.12931965 TLN1,FC=-0.42,p=0.000570744 TLN1,FC=0.22,p=0.191620341 CREB3,FC=0.35,p=1.1e-07 GBA2,FC=0.18,p=0.049762411 GBA2,FC=-0.14,p=0.074910303 NPR2,FC=-0.46,p=1.69e-05 NPR2,FC=-0.89,p=2.81e-13 SPAG8,FC=-1.29,p=4.83e-09 SPAG8,FC=-0.38,p=0.004325887 HINT2,FC=0.14,p=0.049007365 C9orf128,FC=-0.04,p=0.83766558 TMEM8B,FC=-0.26,p=0.059652646 TMEM8B,FC=0.13,p=0.219010433 HRCT1,FC=-1.43,p=3.44e-14 LOC158376,FC=-0.80,p=7.4e-09 OR2S2,FC=0.58,p=0.000687351 RECK,FC=-0.80,p=6.47e-07 RECK,FC=0.12,p=0.556214664 RECK,FC=-0.47,p=3.14e-05 RECK,FC=-2.07,p=1.94e-34 GLIPR2,FC=-1.66,p=3.85e-52 GLIPR2,FC=-0.90,p=1.66e-15 CCIN,FC=-0.74,p=2.35e-06 CLTA,FC=-0.08,p=0.185373137 CLTA,FC=0.01,p=0.898220477 CLTA,FC=-0.21,p=0.003571389 CLTA,FC=-0.10,p=0.425519175 GNE,FC=-0.07,p=0.459822932 RNF38,FC=0.66,p=1.37e-12 RNF38,FC=-0.52,p=9.4e-14 MELK,FC=2.30,p=1.52e-28 PAX5,FC=0.11,p=0.45861156 ZCCHC7,FC=-0.35,p=0.010372038 ZCCHC7,FC=-0.00,p=0.996358635 ZCCHC7,FC=0.09,p=0.502359221 ZCCHC7,FC=0.11,p=0.493352485 ZCCHC7,FC=-0.22,p=0.021716439

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      UNC13B,FC=0.45,p=2.12e-05 UNC13B,FC=-0.85,p=1.09e-05 LOC158381,FC=-2.53,p=9.26e-22 LOC158381,FC=-0.68,p=0.008049582 RUSC2,FC=-0.65,p=4.6e-05 FAM166B,FC=-1.02,p=2.72e-05 TESK1,FC=0.36,p=0.000348477 CD72,FC=0.06,p=0.74695766 SIT1,FC=-0.46,p=0.011684349 CCDC107,FC=-0.42,p=3.03e-05 C9orf100,FC=1.79,p=1.5e-18 C9orf100,FC=1.97,p=9.02e-15 C9orf100,FC=1.74,p=8.47e-17 CA9,FC=2.39,p=2.93e-23 TPM2,FC=0.36,p=0.019747791 TPM2,FC=0.29,p=0.182080016 TPM2,FC=-1.09,p=1.34e-09 TLN1,FC=0.30,p=0.044923778 TLN1,FC=-0.36,p=0.005821259 TLN1,FC=0.19,p=0.300346142 CREB3,FC=-0.05,p=0.643373868 GBA2,FC=0.26,p=0.010306867 GBA2,FC=-0.50,p=3.89e-07 NPR2,FC=-0.26,p=0.023367239 NPR2,FC=-0.96,p=5.9e-10 SPAG8,FC=-1.00,p=3.13e-05 SPAG8,FC=-0.16,p=0.196739237 HINT2,FC=0.16,p=0.131469981 C9orf128,FC=-0.07,p=0.776753411 TMEM8B,FC=-0.24,p=0.113461839 TMEM8B,FC=0.34,p=0.004487992 HRCT1,FC=-2.43,p=1.1e-27 LOC158376,FC=-0.66,p=0.000271616 OR2S2,FC=1.14,p=1.1e-07 RECK,FC=-1.53,p=4.87e-10 RECK,FC=0.15,p=0.523604464 RECK,FC=-0.51,p=4.06e-05 RECK,FC=-2.88,p=5.49e-31 GLIPR2,FC=-1.80,p=8.27e-37 GLIPR2,FC=-0.98,p=2.7e-11 CCIN,FC=-0.79,p=1.53e-05 CLTA,FC=-0.01,p=0.929753155 CLTA,FC=0.17,p=0.055594105 CLTA,FC=0.03,p=0.713815075 CLTA,FC=0.17,p=0.206182108 GNE,FC=-0.38,p=0.001244371 RNF38,FC=1.06,p=3.69e-18 RNF38,FC=-0.65,p=1.84e-14 MELK,FC=3.19,p=2.13e-42 PAX5,FC=0.07,p=0.689123687 ZCCHC7,FC=-1.03,p=2.06e-09 ZCCHC7,FC=-0.46,p=0.001035259 ZCCHC7,FC=-0.31,p=0.010244525 ZCCHC7,FC=-0.14,p=0.381125778 ZCCHC7,FC=-0.56,p=5.05e-06


        Stanford (GSE3398)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      TESK1,FC=-0.02,p=0.929387947 CD72,FC=0.84,p=0.008353477 CA9,FC=0.87,p=0.003053968 TPM2,FC=0.57,p=0.098871516 SPAG8,FC=-0.34,p=0.31753828 RECK,FC=-0.66,p=0.071172362 RECK,FC=-1.70,p=0.000128364 CCIN,FC=-0.50,p=0.167942643 CLTA,FC=0.76,p=0.005581767 GNE,FC=-0.10,p=0.662892051 PAX5,FC=0.23,p=0.564435867

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      TESK1,FC=-0.32,p=0.441195162 CD72,FC=0.50,p=0.281345766 CA9,FC=0.18,p=0.622526599 TPM2,FC=1.26,p=0.000418678 SPAG8,FC=-0.31,p=0.292288993 RECK,FC=-0.40,p=0.496133436 RECK,FC=-1.44,p=0.001219042 CCIN,FC=-0.30,p=0.371705191 CLTA,FC=0.99,p=0.00236215 GNE,FC=0.01,p=0.983458614 PAX5,FC=0.28,p=0.479279838


        Agilent_HS_21.6K (GSE11969)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      UNC13B,FC=0.09,p=0.148540832 UNC13B,FC=-0.23,p=2.38e-05 RUSC2,FC=0.03,p=0.644699148 TESK1,FC=-0.21,p=0.000331108 CD72,FC=-0.30,p=5.86e-05 C9orf100,FC=0.08,p=0.000811494 CA9,FC=0.19,p=0.026240857 TPM2,FC=-0.30,p=0.005011399 TLN1,FC=-0.02,p=0.640306186 GBA2,FC=-0.03,p=0.125623879 SPAG8,FC=-0.19,p=0.011345592 HINT2,FC=-0.01,p=0.68905467 RECK,FC=-0.61,p=1.46e-07 CCIN,FC=-0.05,p=0.054811927 GNE,FC=0.02,p=0.832638996 RNF38,FC=0.01,p=0.774270872 MELK,FC=0.56,p=1.91e-06 PAX5,FC=0.05,p=0.00730662 ZCCHC7,FC=0.04,p=0.409464462

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      UNC13B,FC=0.11,p=0.029000413 UNC13B,FC=-0.32,p=3.38e-09 RUSC2,FC=0.03,p=0.635061364 TESK1,FC=-0.22,p=0.000446252 CD72,FC=-0.33,p=0.000799997 C9orf100,FC=0.08,p=0.00127426 CA9,FC=0.27,p=0.006761617 TPM2,FC=-0.36,p=0.000724182 TLN1,FC=-0.01,p=0.708074264 GBA2,FC=-0.02,p=0.418321294 SPAG8,FC=-0.24,p=0.001726756 HINT2,FC=-0.04,p=0.295652565 RECK,FC=-0.77,p=1.27e-08 CCIN,FC=-0.06,p=0.013756977 GNE,FC=-0.01,p=0.899562352 RNF38,FC=0.00,p=0.941772244 MELK,FC=0.74,p=4.51e-10 PAX5,FC=0.06,p=0.001334299 ZCCHC7,FC=0.01,p=0.812085126


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    Copy Number Alteration Data        (help)
            ( red: amplification / green : deletion)

         Adenocarcinoma          Squamous Cell Carcinoma
        Meyerson Adenocarcinoma (SNP)      Save as a PNG file. Save as a PDF file. Save as a PS file.
      

        GSE17958 Squamous Cell Carcinoma (SNP)      Save as a PNG file. Save as a PDF file. Save as a PS file.
      

        GSE12280_SGOL (SCC / aCGH)      Save as a PNG file. Save as a PDF file. Save as a PS file.
      

      

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    miRNA Expression Data        (help)
            ( red: up-regulation / green : down-regulation)

         Adenocarcinoma          Squamous Cell Carcinoma
        GSE15201
        Adenocarcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picture,Mean=0.00

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picture,Mean=0.00

        GSE18692
        Adenocarcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picture,Mean=0.00

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picture,Mean=0.00

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    Paired (U133A/aCGH) AD Sample Data        (help) (PubMed)       Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: amplification / green : deletion)

UNC13B,FC=-1.00,p=9.31e-21 RUSC2,FC=-0.90,p=1.37e-07 TESK1,FC=-0.03,p=0.602541162 CD72,FC=0.85,p=3.09e-06 SIT1,FC=0.21,p=0.15199809 CA9,FC=0.05,p=0.742144274 TPM2,FC=-0.22,p=0.055757409 TPM2,FC=-0.06,p=0.742224421 TLN1,FC=-0.62,p=6.81e-15 CREB3,FC=0.13,p=0.09426006 NPR2,FC=-0.59,p=9e-05 NPR2,FC=-0.68,p=3.75e-12 SPAG8,FC=-0.14,p=0.269666126 SPAG8,FC=0.28,p=0.012809692 TMEM8B,FC=-0.29,p=0.000331872 OR2S2,FC=-0.68,p=8.61e-16 RECK,FC=-1.73,p=9.04e-29 RECK,FC=-0.03,p=0.824084696 CCIN,FC=-0.69,p=1.28e-10 CLTA,FC=-0.36,p=0.000818697 CLTA,FC=0.43,p=2.26e-10 CLTA,FC=0.41,p=9.44e-12 CLTA,FC=0.20,p=0.000240616 GNE,FC=-0.02,p=0.737652379 RNF38,FC=-0.80,p=3.38e-39 MELK,FC=2.08,p=3.97e-27 PAX5,FC=-0.48,p=0.000460197

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    Array CGH Data        (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: amplification / green : deletion)

, 0/50, 0 , 50/50, 1

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    CGH Minimal Deletion Region Data        (help)      Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: amplification / green : deletion)

PMID=

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    LOH Frequency Data        (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.

Our unpublished data D9S1874, 11/21, 52%

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