IGDB.NSCLC Chromosome View

Chromosome 9
9p24 9p23 9p22 9p21 9p13 9p12 9p11 9q11 9q12 9q13 9q21 9q22 9q31 9q32 9q33 9q34         (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.
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    Lung Cancer Genes with Experimental Evidence         (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: up-regulation / green : down-regulation / gray : mutation)

, , JAK2, 2.19%, 5/228 PTPRD, 4.76%, 9/189 PINX1, 0.53%, 1/189

(Click the gene to hyperlink to gene view.)    

    Gene Expression Microarray Data         (help)
            ( red: up-regulation / green : down-regulation)

         Adenocarcinoma          Squamous Cell Carcinoma
        HG_U95 (Meyerson, GSE2514)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      JAK2,FC=-0.39,p=0.0143225 INSL4,FC=0.65,p=0.009351954 RLN2,FC=0.38,p=0.17760571 RLN1,FC=0.20,p=0.343866326 MLANA,FC=0.29,p=0.210633877 MLANA,FC=0.46,p=0.000136895 MLANA,FC=0.26,p=0.219242991 RANBP6,FC=-0.07,p=0.619884182 IL33,FC=-1.61,p=9.9e-10 UHRF2,FC=0.12,p=0.517657655 GLDC,FC=0.31,p=0.106768823 PTPRD,FC=-0.14,p=0.399620167 PTPRD,FC=-1.78,p=6.21e-09 PTPRD,FC=-1.25,p=1.83e-10 TYRP1,FC=-0.54,p=0.015567628 MPDZ,FC=-0.83,p=0.001064717

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      JAK2,FC=-0.12,p=0.511001368 INSL4,FC=0.16,p=0.29287692 RLN2,FC=0.39,p=0.358908582 RLN1,FC=0.02,p=0.943551593 MLANA,FC=0.14,p=0.639338343 MLANA,FC=0.68,p=0.000839805 MLANA,FC=0.52,p=0.085906912 RANBP6,FC=-0.43,p=0.111905683 IL33,FC=-1.99,p=5.43e-09 UHRF2,FC=-0.07,p=0.808874087 GLDC,FC=0.15,p=0.489158814 PTPRD,FC=-0.15,p=0.608918965 PTPRD,FC=-1.04,p=0.000706596 PTPRD,FC=-0.88,p=0.001282086 TYRP1,FC=-0.51,p=0.107356493 MPDZ,FC=-1.04,p=0.00122274


        HG_U133A (GSE7670, GSE17475, DCLungStudy, GSE4573, GSE10072)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      JAK2,FC=-0.92,p=3.32e-08 JAK2,FC=-0.44,p=5.69e-07 INSL6,FC=-0.29,p=0.017316716 INSL4,FC=0.14,p=0.378167151 RLN2,FC=-0.02,p=0.783820963 RLN1,FC=0.01,p=0.903519168 C9orf46,FC=0.33,p=0.000858096 PDCD1LG2,FC=-0.07,p=0.582734684 ERMP1,FC=-0.19,p=0.024866747 MLANA,FC=-0.22,p=0.106997225 MLANA,FC=0.10,p=0.278319644 RANBP6,FC=-0.06,p=0.462018053 IL33,FC=-2.37,p=1.1e-46 GLDC,FC=0.58,p=0.000112765 KDM4C,FC=-0.37,p=0.002962706 KDM4C,FC=0.07,p=0.135018996 PTPRD,FC=-1.73,p=3.28e-35 PTPRD,FC=-0.30,p=0.038530728 PTPRD,FC=-0.61,p=1.8e-08 PTPRD,FC=-1.42,p=8.36e-44 TYRP1,FC=-1.13,p=1.32e-18 MPDZ,FC=-1.33,p=8.01e-25 MPDZ,FC=-0.90,p=5.87e-30

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      JAK2,FC=-1.01,p=2.63e-15 JAK2,FC=-3.26,p=4.29e-57 INSL6,FC=0.77,p=2.48e-10 INSL4,FC=-1.89,p=8.3e-18 RLN2,FC=2.01,p=9.13e-52 RLN1,FC=0.94,p=9.8e-25 C9orf46,FC=0.55,p=1.15e-07 PDCD1LG2,FC=3.61,p=6.25e-96 ERMP1,FC=2.30,p=2.44e-85 MLANA,FC=1.15,p=1.36e-12 MLANA,FC=0.94,p=3.24e-20 RANBP6,FC=-1.69,p=1.1e-67 IL33,FC=-0.07,p=0.432065796 GLDC,FC=-0.04,p=0.73960877 KDM4C,FC=4.94,p=1.13e-129 KDM4C,FC=-0.14,p=0.104886385 PTPRD,FC=-0.52,p=1.55e-10 PTPRD,FC=-1.66,p=3.5e-16 PTPRD,FC=1.61,p=1.92e-33 PTPRD,FC=1.49,p=6.3e-47 TYRP1,FC=-3.06,p=2.32e-70 MPDZ,FC=-0.80,p=4.16e-17 MPDZ,FC=-5.24,p=5.59e-93


        HG_U133_Plus2 (GSE3141, GSE10245, GSE10445, GSE12667, GSE10799, GSE16538, GSE7307, GSE3526)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      JAK2,FC=-0.89,p=2.68e-11 JAK2,FC=-1.33,p=1.01e-10 JAK2,FC=-1.14,p=4.61e-09 INSL6,FC=0.45,p=0.038839096 INSL4,FC=1.11,p=2.39e-05 RLN2,FC=0.29,p=0.019114295 RLN1,FC=0.02,p=0.903187818 C9orf46,FC=0.31,p=0.00979083 CD274,FC=-0.17,p=0.140317814 PDCD1LG2,FC=-0.42,p=0.077079706 PDCD1LG2,FC=-0.30,p=0.218108525 KIAA1432,FC=0.66,p=1.09e-05 KIAA1432,FC=0.44,p=0.037147133 ERMP1,FC=0.37,p=0.000313142 ERMP1,FC=-0.11,p=0.338584301 MLANA,FC=0.21,p=0.287493065 MLANA,FC=0.39,p=0.063889107 KIAA2026,FC=-0.09,p=0.504272832 KIAA2026,FC=-0.31,p=0.097168124 KIAA2026,FC=0.00,p=0.974517472 KIAA2026,FC=-0.32,p=2.58e-06 RANBP6,FC=-0.21,p=0.007970298 IL33,FC=-2.05,p=2.34e-21 TPD52L3,FC=-0.05,p=0.777292396 TPD52L3,FC=0.12,p=0.470566798 UHRF2,FC=0.23,p=0.002634483 GLDC,FC=0.94,p=7.03e-06 KDM4C,FC=0.08,p=0.272389731 KDM4C,FC=-1.09,p=7.72e-10 KDM4C,FC=-0.20,p=0.146603772 KDM4C,FC=0.22,p=0.2505079 KDM4C,FC=-1.04,p=1.2e-07 C9orf123,FC=0.14,p=0.09101564 C9orf123,FC=-0.52,p=1.03e-06 PTPRD,FC=0.51,p=0.036267391 PTPRD,FC=0.09,p=0.617390899 PTPRD,FC=-0.39,p=0.03193213 PTPRD,FC=-0.37,p=0.117275569 PTPRD,FC=-1.82,p=2.3e-20 PTPRD,FC=-1.86,p=5.18e-23 PTPRD,FC=0.78,p=0.000571608 TYRP1,FC=-1.82,p=4.05e-20 C9orf150,FC=-1.10,p=7.08e-14 C9orf150,FC=-0.18,p=0.068220618 MPDZ,FC=-0.70,p=2.32e-10 MPDZ,FC=-1.15,p=2.81e-13

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      JAK2,FC=-1.53,p=3.13e-15 JAK2,FC=-2.04,p=6.87e-16 JAK2,FC=-1.88,p=2.04e-11 INSL6,FC=0.17,p=0.41577748 INSL4,FC=0.44,p=0.018574384 RLN2,FC=0.05,p=0.732058761 RLN1,FC=0.16,p=0.311834516 C9orf46,FC=0.14,p=0.238757929 CD274,FC=0.03,p=0.823173968 PDCD1LG2,FC=-0.78,p=0.004975975 PDCD1LG2,FC=-0.65,p=0.01945849 KIAA1432,FC=0.94,p=1.62e-07 KIAA1432,FC=0.40,p=0.124759234 ERMP1,FC=1.09,p=1.73e-17 ERMP1,FC=0.47,p=0.000854003 MLANA,FC=-0.15,p=0.538851724 MLANA,FC=0.84,p=0.000243208 KIAA2026,FC=0.21,p=0.113794963 KIAA2026,FC=-0.74,p=0.00037534 KIAA2026,FC=0.01,p=0.908230398 KIAA2026,FC=-0.16,p=0.039118924 RANBP6,FC=-0.60,p=9.23e-10 IL33,FC=-2.62,p=3.19e-19 TPD52L3,FC=-0.17,p=0.383708402 TPD52L3,FC=0.08,p=0.667516009 UHRF2,FC=0.29,p=0.000759797 GLDC,FC=1.15,p=1.42e-06 KDM4C,FC=0.09,p=0.234740688 KDM4C,FC=-1.71,p=3.77e-16 KDM4C,FC=-0.76,p=7.35e-06 KDM4C,FC=0.27,p=0.217190763 KDM4C,FC=-1.28,p=3.35e-10 C9orf123,FC=0.24,p=0.011528993 C9orf123,FC=-0.70,p=8.88e-10 PTPRD,FC=0.36,p=0.201085823 PTPRD,FC=0.81,p=0.000182925 PTPRD,FC=-0.44,p=0.023955157 PTPRD,FC=-0.02,p=0.924430488 PTPRD,FC=-1.38,p=5.62e-09 PTPRD,FC=-1.35,p=2.75e-08 PTPRD,FC=0.55,p=0.026463767 TYRP1,FC=-1.90,p=1.37e-21 C9orf150,FC=-1.79,p=3.84e-21 C9orf150,FC=-0.61,p=7.97e-07 MPDZ,FC=-0.68,p=4.19e-12 MPDZ,FC=-1.52,p=2.28e-13


        Stanford (GSE3398)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      INSL4,FC=-0.03,p=0.972386509 RLN1,FC=-0.48,p=0.45613084 RLN1,FC=-0.42,p=0.372736758 MLANA,FC=-1.35,p=0.023357782 MLANA,FC=0.07,p=0.840770759 RANBP6,FC=0.19,p=0.392693457 GLDC,FC=1.26,p=0.000592569 PTPRD,FC=-0.54,p=0.101122569 TYRP1,FC=-2.27,p=2.88e-05 MPDZ,FC=-0.28,p=0.521087443

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      INSL4,FC=-0.87,p=0.03880203 RLN1,FC=0.37,p=0.551208574 RLN1,FC=0.48,p=0.27692424 MLANA,FC=-0.92,p=0.211031452 MLANA,FC=0.28,p=0.502032734 RANBP6,FC=0.15,p=0.622175844 GLDC,FC=1.17,p=0.005702499 PTPRD,FC=0.02,p=0.94340179 TYRP1,FC=-1.96,p=0.008087804 MPDZ,FC=-0.19,p=0.613966473


        Agilent_HS_21.6K (GSE11969)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      JAK2,FC=0.21,p=0.038168024 INSL6,FC=0.02,p=0.717452581 INSL4,FC=0.16,p=0.192761129 RLN2,FC=0.19,p=0.000102754 RLN1,FC=0.04,p=0.303760096 C9orf46,FC=0.07,p=0.024740307 PDCD1LG2,FC=0.01,p=0.692393507 KIAA1432,FC=-0.01,p=0.643777747 MLANA,FC=0.05,p=0.081591749 KIAA2026,FC=-0.06,p=0.463147178 KIAA2026,FC=0.04,p=0.076823545 RANBP6,FC=0.00,p=0.937723142 UHRF2,FC=-0.02,p=0.754901918 UHRF2,FC=-0.04,p=0.144375673 GLDC,FC=0.02,p=0.387611006 C9orf123,FC=-0.21,p=7e-05 PTPRD,FC=-0.05,p=0.123954321 TYRP1,FC=-0.31,p=7.43e-05 TYRP1,FC=-0.02,p=0.216991645 C9orf150,FC=-0.05,p=0.488901004 MPDZ,FC=-0.05,p=0.424783195

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      JAK2,FC=0.22,p=0.022136263 INSL6,FC=0.02,p=0.839699032 INSL4,FC=0.10,p=0.088507901 RLN2,FC=0.19,p=0.000474158 RLN1,FC=0.01,p=0.739025415 C9orf46,FC=0.08,p=0.014185697 PDCD1LG2,FC=-0.00,p=0.969754428 KIAA1432,FC=-0.01,p=0.834842619 MLANA,FC=0.06,p=0.147897888 KIAA2026,FC=-0.01,p=0.88250722 KIAA2026,FC=0.06,p=0.00926854 RANBP6,FC=0.01,p=0.618429447 UHRF2,FC=-0.02,p=0.690565336 UHRF2,FC=-0.06,p=0.010776712 GLDC,FC=0.02,p=0.416034798 C9orf123,FC=-0.23,p=0.000349528 PTPRD,FC=-0.01,p=0.863603151 TYRP1,FC=-0.40,p=1.83e-09 TYRP1,FC=-0.03,p=0.15219289 C9orf150,FC=-0.15,p=0.036290743 MPDZ,FC=-0.12,p=0.010444741


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    Copy Number Alteration Data        (help)
            ( red: amplification / green : deletion)

         Adenocarcinoma          Squamous Cell Carcinoma
        Meyerson Adenocarcinoma (SNP)      Save as a PNG file. Save as a PDF file. Save as a PS file.
      

        GSE17958 Squamous Cell Carcinoma (SNP)      Save as a PNG file. Save as a PDF file. Save as a PS file.
      

        GSE12280_SGOL (SCC / aCGH)      Save as a PNG file. Save as a PDF file. Save as a PS file.
      

      

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    miRNA Expression Data        (help)
            ( red: up-regulation / green : down-regulation)

         Adenocarcinoma          Squamous Cell Carcinoma
        GSE15201
        Adenocarcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picture,Mean=0.00

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picture,Mean=0.00

        GSE18692
        Adenocarcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picture,Mean=0.00

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picture,Mean=0.00

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    Paired (U133A/aCGH) AD Sample Data        (help) (PubMed)       Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: amplification / green : deletion)

JAK2,FC=-0.56,p=0.000241719 JAK2,FC=-0.36,p=3.57e-06 INSL6,FC=-0.54,p=5.03e-05 INSL4,FC=-0.21,p=0.314430116 RLN2,FC=-0.27,p=0.00089611 RLN1,FC=-0.21,p=0.015001197 C9orf46,FC=0.17,p=0.115029874 PDCD1LG2,FC=-0.08,p=0.572793537 ERMP1,FC=-0.44,p=1.18e-08 MLANA,FC=-0.34,p=0.028674628 MLANA,FC=-0.53,p=0.000243368 RANBP6,FC=-0.04,p=0.597778712 IL33,FC=-1.81,p=2.57e-21 GLDC,FC=0.44,p=0.006050124 KDM4C,FC=-0.54,p=3.04e-05 KDM4C,FC=-0.13,p=0.015581658 PTPRD,FC=-1.61,p=7.86e-33 PTPRD,FC=-0.29,p=0.082850093 PTPRD,FC=-0.86,p=3.88e-11 PTPRD,FC=-1.45,p=3.69e-32 TYRP1,FC=-0.81,p=5.33e-08 MPDZ,FC=-1.19,p=5.51e-20 MPDZ,FC=-0.79,p=3.61e-19

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    Array CGH Data        (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: amplification / green : deletion)

RP11-509D8, 0/50, 0 RP11-509D8, 12/50, 0.24 RP11-218I7, 1/50, 0.02 RP11-218I7, 10/50, 0.2 RP11-106A1, 7/50, 0.14 RP11-106A1, 6/50, 0.12 RP11-29B9, 2/50, 0.04 RP11-29B9, 0/50, 0 RP11-175E13, 1/50, 0.02 RP11-175E13, 17/50, 0.34 RP11-527D15, 1/50, 0.02 RP11-527D15, 15/50, 0.3 RP11-19G1, 0/50, 0 RP11-19G1, 11/50, 0.22 RP11-23D5, 0/50, 0 RP11-23D5, 13/50, 0.26 RP11-352F21, 0/50, 0 RP11-352F21, 13/50, 0.26 RP11-446F13, 0/50, 0 RP11-446F13, 19/50, 0.38 RP11-187K14, 2/50, 0.04 RP11-187K14, 9/50, 0.18 RP11-413D24, 2/50, 0.04 RP11-413D24, 24/50, 0.48

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    CGH Minimal Deletion Region Data        (help)      Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: amplification / green : deletion)

PMID=12599234 PMID=14970871 PMID=15093586

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    LOH Frequency Data        (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.

Our unpublished data D9S2169, 13/35, 37% Our unpublished data D9S2156, 10/32, 31% Our unpublished data D9S286, 4/7, 57% Our unpublished data D9S921, 12/22, 55% Our unpublished data D9S269, 14/31, 45% PMID=10987304 D9S286, 14/19, 74% PMID=11980668 D9S254, 22/31, 71% D9S286, 7/20, 35% PMID=15900585 D9S286, 12/23, 52%

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