IGDB.NSCLC Chromosome View

Chromosome 7
7p22 7p21 7p15 7p14 7p13 7p12 7p11 7q11 7q21 7q22 7q31 7q32 7q33 7q34 7q35 7q36         (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.
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    Lung Cancer Genes with Experimental Evidence         (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: up-regulation / green : down-regulation / gray : mutation)

EGFR, up, 69/125(55%) EGFR, up, 92/167(55%) EGFR, up, 47/60(78%) EGFR, up, 86/172(50%) EGFR, up, 73/130(56%) EGFR, up, 31/96(32%) EGFR, up, 94/169(56%) EGFR, up, 66/111(59%) EGFR, up, 101/130(78%) EGFR, up, 20/30(67%) EGFR, up, 58/82(71%) EGFR, up, 121/200(61%) EGFR, up, 48/72(67%) EGFR, 34.22%, 4845/14158

(Click the gene to hyperlink to gene view.)    

    Gene Expression Microarray Data         (help)
            ( red: up-regulation / green : down-regulation)

         Adenocarcinoma          Squamous Cell Carcinoma
        HG_U95 (Meyerson, GSE2514)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      SEC61G,FC=0.63,p=1.09e-06 EGFR,FC=-0.12,p=0.607573493 EGFR,FC=0.62,p=0.028878125 GBAS,FC=0.04,p=0.771800959 PSPH,FC=0.80,p=0.005669543 PSPH,FC=0.95,p=0.011404608 CCT6A,FC=0.25,p=0.033700638 PHKG1,FC=0.30,p=0.023512933

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      SEC61G,FC=0.50,p=0.0020429 EGFR,FC=0.37,p=0.147832839 EGFR,FC=1.07,p=0.004167734 GBAS,FC=-0.17,p=0.26316763 PSPH,FC=1.30,p=0.000483266 PSPH,FC=1.54,p=0.00146832 CCT6A,FC=0.43,p=0.000890324 PHKG1,FC=-0.30,p=0.122169585


        HG_U133A (GSE7670, GSE17475, DCLungStudy, GSE4573, GSE10072)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      SEC61G,FC=0.97,p=8.85e-43 EGFR,FC=0.05,p=0.36279473 EGFR,FC=-0.29,p=7.03e-05 EGFR,FC=0.07,p=0.62967159 EGFR,FC=0.22,p=0.058342933 EGFR,FC=0.01,p=0.971040267 EGFR,FC=0.14,p=0.33479461 LANCL2,FC=0.45,p=9.01e-10 MRPS17,FC=0.76,p=2.9e-29 GBAS,FC=0.29,p=0.000975569 PSPH,FC=0.96,p=4.71e-18 PSPH,FC=0.98,p=0.000499988 CCT6A,FC=0.44,p=5.08e-07 CCT6A,FC=1.02,p=1.55e-42 PHKG1,FC=-0.45,p=3.13e-07 CHCHD2,FC=0.36,p=3.16e-10

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      SEC61G,FC=-1.31,p=2.67e-16 EGFR,FC=-1.24,p=1.07e-46 EGFR,FC=7.56,p=1.8e-194 EGFR,FC=-3.65,p=1.38e-101 EGFR,FC=2.59,p=9.31e-112 EGFR,FC=3.51,p=1.13e-36 EGFR,FC=4.62,p=1.43e-110 LANCL2,FC=1.22,p=1.82e-41 MRPS17,FC=-0.73,p=1.88e-27 GBAS,FC=-0.06,p=0.488482977 PSPH,FC=2.32,p=1.98e-45 PSPH,FC=1.69,p=2.85e-07 CCT6A,FC=0.01,p=0.899826995 CCT6A,FC=1.80,p=2.32e-76 PHKG1,FC=0.88,p=1.56e-15 CHCHD2,FC=-6.99,p=3.46e-144


        HG_U133_Plus2 (GSE3141, GSE10245, GSE10445, GSE12667, GSE10799, GSE16538, GSE7307, GSE3526)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      VSTM2A,FC=0.09,p=0.583792318 VSTM2A,FC=0.47,p=0.035445576 SEC61G,FC=0.68,p=1.75e-16 TCEA1,FC=-0.21,p=0.261490497 EGFR,FC=-0.66,p=0.000325503 EGFR,FC=-0.46,p=0.055331971 EGFR,FC=0.29,p=0.175864536 EGFR,FC=0.46,p=0.00026381 EGFR,FC=0.34,p=0.000120822 EGFR,FC=0.50,p=0.027854343 EGFR,FC=0.01,p=0.958697235 EGFR,FC=1.17,p=2.7e-05 EGFR,FC=0.42,p=0.001682164 EGFR,FC=-0.36,p=0.027892368 EGFR,FC=0.90,p=2.23e-05 LANCL2,FC=-0.02,p=0.925272289 LANCL2,FC=-0.29,p=0.00010867 LANCL2,FC=0.28,p=0.001387461 ZNF713,FC=-0.37,p=0.090980599 MRPS17,FC=0.96,p=3.85e-24 GBAS,FC=0.61,p=0.000291498 GBAS,FC=-0.03,p=0.744369434 PSPH,FC=0.93,p=0.003357336 PSPH,FC=1.10,p=5.85e-20 PSPH,FC=1.11,p=1.86e-07 CCT6A,FC=0.41,p=4.52e-08 CCT6A,FC=0.50,p=4.5e-09 SUMF2,FC=0.98,p=1.14e-19 PHKG1,FC=0.40,p=0.036820034 CHCHD2,FC=0.57,p=2.33e-18

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      VSTM2A,FC=0.02,p=0.892396871 VSTM2A,FC=0.64,p=0.009424857 SEC61G,FC=0.85,p=1.14e-17 TCEA1,FC=-0.59,p=0.002706796 EGFR,FC=-0.53,p=0.015904522 EGFR,FC=-0.56,p=0.010394364 EGFR,FC=0.41,p=0.089047723 EGFR,FC=0.86,p=2.32e-08 EGFR,FC=0.34,p=0.001910324 EGFR,FC=0.65,p=0.012462796 EGFR,FC=0.18,p=0.230181892 EGFR,FC=1.21,p=3.45e-06 EGFR,FC=1.27,p=1.19e-13 EGFR,FC=0.28,p=0.102846725 EGFR,FC=1.13,p=1.19e-06 LANCL2,FC=0.14,p=0.484975722 LANCL2,FC=-0.11,p=0.196439835 LANCL2,FC=0.57,p=2.48e-06 ZNF713,FC=-1.14,p=1.42e-05 MRPS17,FC=1.18,p=3.75e-21 GBAS,FC=0.62,p=0.001168185 GBAS,FC=-0.30,p=0.005631731 PSPH,FC=1.61,p=8.38e-06 PSPH,FC=1.79,p=5.61e-20 PSPH,FC=1.28,p=7.23e-07 CCT6A,FC=0.74,p=1.77e-11 CCT6A,FC=0.71,p=9.23e-11 SUMF2,FC=0.74,p=1.88e-09 PHKG1,FC=1.26,p=3.5e-09 CHCHD2,FC=0.74,p=7.23e-21


        Stanford (GSE3398)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      SEC61G,FC=0.60,p=0.133444861 EGFR,FC=0.32,p=0.613736886 EGFR,FC=0.19,p=0.764737625 EGFR,FC=-0.22,p=0.477131183 PSPH,FC=0.70,p=0.022572284 CCT6A,FC=1.00,p=0.005649431 CCT6A,FC=1.09,p=0.000356403 CCT6A,FC=-1.31,p=1.15e-05

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      SEC61G,FC=0.63,p=0.041139429 EGFR,FC=0.63,p=0.108025189 EGFR,FC=0.30,p=0.461800626 EGFR,FC=-0.35,p=0.509777198 PSPH,FC=0.98,p=0.002832394 CCT6A,FC=0.98,p=0.004642733 CCT6A,FC=0.99,p=0.008050117 CCT6A,FC=-1.08,p=8.67e-05


        Agilent_HS_21.6K (GSE11969)
        Adenocarcinoma      Save as a PNG file. Save as a PDF file. Save as a PS file.
      SEC61G,FC=0.20,p=0.056691356 EGFR,FC=0.03,p=0.46125061 LANCL2,FC=0.03,p=0.706346524 MRPS17,FC=0.34,p=0.006268589 GBAS,FC=0.22,p=0.010665865 PSPH,FC=0.33,p=0.009735997 CCT6A,FC=0.32,p=0.002911463 SUMF2,FC=-0.06,p=0.024029613 CHCHD2,FC=0.34,p=0.001881054

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      SEC61G,FC=0.24,p=0.000734696 EGFR,FC=0.03,p=0.484948803 LANCL2,FC=0.12,p=0.119881119 MRPS17,FC=0.44,p=1.46e-05 GBAS,FC=0.14,p=0.007448561 PSPH,FC=0.35,p=0.019123661 CCT6A,FC=0.44,p=3.01e-07 SUMF2,FC=-0.09,p=0.002049787 CHCHD2,FC=0.35,p=4.7e-06


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    Copy Number Alteration Data        (help)
            ( red: amplification / green : deletion)

         Adenocarcinoma          Squamous Cell Carcinoma
        Meyerson Adenocarcinoma (SNP)      Save as a PNG file. Save as a PDF file. Save as a PS file.
      

        GSE17958 Squamous Cell Carcinoma (SNP)      Save as a PNG file. Save as a PDF file. Save as a PS file.
      

        GSE12280_SGOL (SCC / aCGH)      Save as a PNG file. Save as a PDF file. Save as a PS file.
      

      

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    miRNA Expression Data        (help)
            ( red: up-regulation / green : down-regulation)

         Adenocarcinoma          Squamous Cell Carcinoma
        GSE15201
        Adenocarcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picture,Mean=0.00

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picture,Mean=0.00

        GSE18692
        Adenocarcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picture,Mean=0.00

        Squamous Cell Carcinoma       Save as a PNG file. Save as a PDF file. Save as a PS file.
      array picture,Mean=0.00

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    Paired (U133A/aCGH) AD Sample Data        (help) (PubMed)       Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: amplification / green : deletion)

SEC61G,FC=0.78,p=5.32e-27 EGFR,FC=-0.32,p=0.000944635 EGFR,FC=-0.57,p=1.64e-10 EGFR,FC=0.48,p=0.001370492 EGFR,FC=0.28,p=0.02241963 EGFR,FC=0.21,p=0.261609898 EGFR,FC=0.49,p=0.002863402 LANCL2,FC=0.40,p=1.62e-06 MRPS17,FC=0.62,p=6.58e-19 GBAS,FC=0.51,p=1.84e-09 PSPH,FC=1.20,p=1.02e-17 PSPH,FC=1.34,p=5.08e-05 CCT6A,FC=0.45,p=9.35e-08 CCT6A,FC=0.93,p=6.23e-32 PHKG1,FC=-0.63,p=1.18e-08 CHCHD2,FC=0.26,p=7.52e-06

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    Array CGH Data        (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: amplification / green : deletion)

RP11-449G3, 8/50, 0.16 RP11-449G3, 3/50, 0.06 RP5-1091E12, 7/50, 0.14 RP5-1091E12, 4/50, 0.08 RP11-339F13, 11/50, 0.22 RP11-339F13, 2/50, 0.04 RP4-725G10, 7/50, 0.14 RP4-725G10, 0/50, 0 RP11-10F11, 8/50, 0.16 RP11-10F11, 4/50, 0.08

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    CGH Minimal Deletion Region Data        (help)      Save as a PNG file. Save as a PDF file. Save as a PS file.
            ( red: amplification / green : deletion)

PMID=12367789 PMID=14581340 PMID=15093586 PMID=15093586 PMID=16322280 PMID=9591638

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    LOH Frequency Data        (help)       Save as a PNG file. Save as a PDF file. Save as a PS file.

Our unpublished data D7S2550, 19/35, 54% Our unpublished data D7S659, 18/45, 40%

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