IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene B3GNT3 Ensembl ENSG00000179913 Chromosome 19 Start 17766919 End 17785385
Description UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (Beta3Gn-T3)(BGnT-3)(EC 2.4.1.-)(Core 1 extending beta-1,3-N-acetylglucosaminyltransferase)(Core1-beta3GlcNAcT)(Beta-1,3-galactosyltransferase 8)(Beta-1,3-GalTase 8)(Beta3Gal-T8)(b3Gal-T8)(Beta-3-Gx-T8)(UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8)(UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y2A9]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 13528
     Entrez Gene : 10331
     UCSC : uc002nhl.1
     GeneCards : 13528
     RefSeq : NM_014256
     CCDS : CCDS12364.1
     Uniprot : Q9Y2A9
     Interpro : Q9Y2A9
     OMIM : 605863
     GeneTests : B3GNT3
     CGAP : B3GNT3
     PMID : 10072769

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  36832_at  1.44  3.79e-15  1.23e-13  1.27  1.56e-6  9.34e-6
 HG_U133A  204856_at  2.08  7.59e-60  6.22e-58  1.98  2.59e-64  7.54e-64
 HG_U133_Plus2  204856_at  2.19  5.44e-35  6.49e-33  1.75  3.29e-18  3.73e-17
 Stanford  21724  1.76  4.72e-4  8.91e-3  0.77  1.72e-1  3.87e-1
 Agilent_HS_21.6K  20211  0.66  5.82e-6  1.11e-4  0.37  4.26e-3  1.79e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  204856_at  -0.68  1.23e-1  7.92e-1  0.04  8.81e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 36832_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 204856_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 204856_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 21724    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 20211    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
b3gnt3 nhl Our results suggest that genetic variation in genes associated with immune response (TRAF1, RIPK3, BAT2, and TLR6), mitogen-activated protein kinase (MAPK) signaling (MAP3K5, DUSP2, and CREB1), lymphocyte trafficking and migration (B3GNT3, SELPLG, and LSP 17827388 Human

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