IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene LMTK3 Ensembl ENSG00000142235 Chromosome 19 Start 53680340 End 53708258
Description Serine/threonine-protein kinase LMTK3 Precursor (EC 2.7.11.1)(Lemur tyrosine kinase 3) [Source:UniProtKB/Swiss-Prot;Acc:Q96Q04]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :
     HGNC : 19295
     Entrez Gene : 114783
     UCSC : uc002pjk.2
     GeneCards : 19295
     RefSeq : NM_001080434
     CCDS : CCDS46136.1
     Uniprot : Q96Q04
     Interpro : Q96Q04
     GeneTests : LMTK3
     CGAP : LMTK3

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Somatic Mutaions        (help)
Lung cancer Adenocarcinoma Squamous Cell Carcinoma
Unique Mutated Samples % Mutated Total Unique
Samples
Unique Mutated
Samples
% Mutated Total Unique
Samples
Unique Mutated
Samples
% Mutated Total Unique
Samples
3 1.33 225 2 1.03 195 1 14.29 7
Sample datas
Sample Name Histology Subtype DNA Mutation Protein Mutation Mutation Description Zygosity Genomic Co-ordinates NCBI36 Pubmed
17210 AD c.4153G>C p.E1385Q Substitution - Missense Heterozygous 19:53686294-5368629418948947
17210 AD c.1155G>T p.K385N Substitution - Missense Heterozygous 19:53696106-5369610618948947
17759 AD c.3157G>C p.E1053Q Substitution - Missense Heterozygous 19:53692885-5369288518948947
17759 AD c.2761G>T p.E921* Substitution - Nonsense Heterozygous 19:53693281-5369328118948947
PD0269a SCC c.161A>G p.Y54C Substitution - Missense Unknown 19:53705622-5370562216140923

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133_Plus2  1557103_a_at  0.62  2.53e-4  7.45e-4  1.11  1.67e-10  7.81e-10
 Agilent_HS_21.6K  15337  -0.00  8.92e-1  9.40e-1  0.00  9.02e-1  9.42e-1

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133_Plus2 - 1557103_a_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 15337    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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