IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene PTPN14 Ensembl ENSG00000152104 Chromosome 1 Start 212597714 End 212791574
Description Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48)(Protein-tyrosine phosphatase pez) [Source:UniProtKB/Swiss-Prot;Acc:Q15678]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 9647
     Entrez Gene : 5784
     UCSC : uc001hkk.1
     GeneCards : 9647
     RefSeq : NM_005401
     CCDS : CCDS1514.1
     Uniprot : Q15678
     Interpro : Q15678
     OMIM : 603155
     GeneTests : PTPN14
     CGAP : PTPN14
     PMID : 7733990

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  801_at  0.51  4.32e-3  1.13e-2  1.09  7.99e-5  3.26e-4
 HG_U133A  205503_at  0.05  4.34e-1  4.89e-1  0.57  1.90e-6  2.23e-6
 HG_U133_Plus2  205503_at  0.43  1.90e-3  4.63e-3  1.18  8.28e-14  5.65e-13
 Stanford  10856  0.65  4.84e-2  1.52e-1  1.16  8.63e-3  6.22e-2
 Agilent_HS_21.6K  9410  0.21  4.77e-4  4.21e-3  0.35  2.08e-6  2.93e-5

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  205503_at  -0.26  2.81e-1  8.69e-1  -0.16  3.50e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 801_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 205503_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 205503_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 10856    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 9410    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
pez tumour We have isolated cDNAs from normal human breast tissue and breast tumour cells that encode a protein (pez) with features of a novel non-receptor tyrosine phosphatase possessing N-terminal sequence homology to the ezrin-band 4.1-merlin-radixin protein fami 7733990 Human
cytoskeletal-associated protein tyrosine phosphatase human hepatocellular carcinoma Expression of cytoskeletal-associated protein tyrosine phosphatase PTPH1 mRNA in human hepatocellular carcinoma. 7874267 Human
ptpn14 cancers A mutational analysis of the tyrosine phosphatase gene superfamily in human cancers identified 83 somatic mutations in six PTPs (PTPRF, PTPRG, PTPRT, PTPN3, PTPN13, PTPN14), affecting 26% of colorectal cancers and a smaller fraction of lung, breast, and g 15155950 Human
ptpn14 colorectal cancers A mutational analysis of the tyrosine phosphatase gene superfamily in human cancers identified 83 somatic mutations in six PTPs (PTPRF, PTPRG, PTPRT, PTPN3, PTPN13, PTPN14), affecting 26% of colorectal cancers and a smaller fraction of lung, breast, and g 15155950 Human
ptpn14 gastric cancers A mutational analysis of the tyrosine phosphatase gene superfamily in human cancers identified 83 somatic mutations in six PTPs (PTPRF, PTPRG, PTPRT, PTPN3, PTPN13, PTPN14), affecting 26% of colorectal cancers and a smaller fraction of lung, breast, and g 15155950 Human
pez breast tumour We have isolated cDNAs from normal human breast tissue and breast tumour cells that encode a protein (pez) with features of a novel non-receptor tyrosine phosphatase possessing N-terminal sequence homology to the ezrin-band 4.1-merlin-radixin protein fami 7733990 Human

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