IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene RANBP1 Ensembl ENSG00000099901 Chromosome 22 Start 18484947 End 18494878
Description Ran-specific GTPase-activating protein (Ran-binding protein 1)(RanBP1) [Source:UniProtKB/Swiss-Prot;Acc:P43487]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 9847
     Entrez Gene : 5902
     UCSC : uc002zro.1
     GeneCards : 9847
     RefSeq : NM_002882
     CCDS : CCDS13775.1
     Uniprot : P43487
     Interpro : P43487
     OMIM : 601180
     GeneTests : RANBP1
     CGAP : RANBP1
     PMID : 7616957

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  41342_at  0.31  9.70e-3  2.28e-2  1.25  7.81e-14  1.95e-12
 HG_U133A  202482_x_at  0.55  7.71e-6  1.81e-5  5.41  1.24e-102  9.03e-102
 HG_U133A  202483_s_at  0.86  6.86e-22  6.16e-21  -0.83  7.37e-11  9.36e-11
 HG_U133A  221915_s_at  -0.06  4.78e-1  5.32e-1  -1.15  1.38e-18  1.97e-18
 HG_U133_Plus2  202482_x_at  0.74  8.69e-6  3.35e-5  0.71  5.32e-4  1.07e-3
 HG_U133_Plus2  202483_s_at  0.91  7.27e-16  1.09e-14  1.72  2.09e-31  1.14e-29
 HG_U133_Plus2  221915_s_at  0.33  5.04e-2  8.47e-2  1.00  7.46e-10  3.24e-9
 Stanford  764  1.03  1.46e-3  1.87e-2  1.57  1.51e-4  3.72e-3
 Agilent_HS_21.6K  20396  0.35  5.34e-5  7.15e-4  0.65  3.36e-9  1.19e-7

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  202482_x_at  -0.07  8.81e-1  9.92e-1  -0.43  1.37e-1  1.00e+0
 HG_U133A  202483_s_at  -0.19  5.63e-1  9.43e-1  -0.07  7.15e-1  1.00e+0
 HG_U133A  221915_s_at  -0.10  7.35e-1  9.74e-1  0.16  4.90e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 41342_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 202482_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 202483_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 221915_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 202482_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 202483_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 221915_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 764    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 20396    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
ranbp1 metastasis Some of them belonged to some important signal pathways related with cell proliferation and metastasis, such as DDK1, ILK, MMP-1 and COL11A1 in Wnt/beta-catenin signal pathway, ILK in ILK signal pathway, EpHB2 in Eph-Ephrins signal pathway, ROCK2 in RhoA 16159426 Human

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