IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene SERPINA4 Ensembl ENSG00000100665 Chromosome 14 Start 94097536 End 94105994
Description Kallistatin Precursor (Kallikrein inhibitor)(Protease inhibitor 4)(Serpin A4) [Source:UniProtKB/Swiss-Prot;Acc:P29622]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 8948
     Entrez Gene : 5267
     UCSC : uc001ydk.2
     GeneCards : 8948
     RefSeq : NM_006215
     CCDS : CCDS9927.1
     Uniprot : P29622
     Interpro : P29622
     OMIM : 147935
     GeneTests : SERPINA4
     CGAP : SERPINA4
     PMID : 8227002

< Top >


Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  32106_at  0.63  7.94e-5  3.33e-4  0.78  2.64e-3  7.21e-3
 HG_U133A  213874_at  -0.14  8.76e-2  1.16e-1  1.56  1.08e-75  3.97e-75
 HG_U133_Plus2  213874_at  0.64  3.11e-3  7.21e-3  0.76  7.42e-4  1.46e-3
 Stanford  11610  1.32  8.86e-3  5.96e-2  1.45  3.11e-3  3.05e-2
 Agilent_HS_21.6K  17953  0.17  3.05e-4  2.97e-3  0.16  4.01e-4  2.54e-3

< Top >


Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  213874_at  -0.04  8.82e-1  9.92e-1  -0.40  3.99e-2  1.00e+0

< Top >


Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 32106_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 213874_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 213874_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 11610    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 17953    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

< Top >


Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
kallistatin tumor Kallistatin is a new inhibitor of angiogenesis and tumor growth. 12384424 Human
kallistatin hyperplasia Our previous study showed that kallistatin plays a role in neointima hyperplasia. 12384424 Human
kallistatin tumor These results demonstrate a novel role of kallistatin in the inhibition of angiogenesis and tumor growth. 12384424 Human
kallistatin inflammatory bowel disease The difference in distribution and levels of ITK and kallistatin in protein and mRNA in patients with inflammatory bowel disease (IBD) compared to controls suggest a role in inflammatory state. 12810351 Human
kallistatin prostate carcinoma Expression of kallistatin mRNA in platelets, neutrophils, lymphocytes, monocytes, endothelial cells, hepatocytes, and colon and prostate carcinoma cells was identified by reverse transcription-polymerase chain reaction followed by Southern blot analysis. 8648266 Human
kallistatin colonic carcinoma In a Southern blot analysis following reverse transcription and polymerase chain reaction, kallistatin was found to be expressed in human liver, stomach, pancreas, kidney, aorta, testes, prostate, artery, atrium, ventricle, lung, renal proximal tubular ce 8227002 Human
kallistatin tumor Our recent studies showed that kallikrein promoted angiogenesis, whereas kallistatin inhibited angiogenesis and tumor growth. 12734113 Human
kallistatin inflammatory bowel disease Immunolocalization and expression of kallistatin and tissue kallikrein in human inflammatory bowel disease. 12757180 Human
kallistatin ibd The difference in distribution and levels of ITK and kallistatin in protein and mRNA in patients with inflammatory bowel disease (IBD) compared to controls suggest a role in inflammatory state. 12810351 Human

< Top >


Download all image files.
Save all PNG files.    Save all PDF files.    Save all PS files.