IGDB.NSCLC Gene View
Gene Information Somatic Mutations Microarray Gene Expression Result Treatment Result Microarray Sample Data
 
Gene Information        (help)
Gene STK24 Ensembl ENSG00000102572 Chromosome 13 Start 97900456 End 98027397
Description Serine/threonine-protein kinase 24 (EC 2.7.11.1)(STE20-like kinase MST3)(MST-3)(Mammalian STE20-like protein kinase 3) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y6E0]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 11403
     Entrez Gene : 8428
     UCSC : uc001vnn.1
     GeneCards : 11403
     RefSeq : NM_001032296
     CCDS : CCDS9488.1
     Uniprot : Q9Y6E0
     Interpro : Q9Y6E0
     OMIM : 604984
     GeneTests : STK24
     CGAP : STK24
     PMID : 9353338

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Somatic Mutaions        (help)
Lung cancer Adenocarcinoma Squamous Cell Carcinoma
Unique Mutated Samples % Mutated Total Unique
Samples		 Unique Mutated
Samples		 % Mutated Total Unique
Samples		 Unique Mutated
Samples		 % Mutated Total Unique
Samples
1 0.44 225 1 0.51 195 0 0.00 7
Sample datas
Sample Name Histology Subtype DNA Mutation Protein Mutation Mutation Description Zygosity Genomic Co-ordinates NCBI36 Pubmed
17262 AD c.1241C>T p.A414V Substitution - Missense Heterozygous 13:97907477-9790747718948947

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  40473_at  0.08  4.07e-1  5.14e-1  0.31  3.92e-3  1.02e-2
 HG_U133A  208854_s_at  0.38  4.20e-9  1.38e-8  -6.54  1.00e-140  2.35e-139
 HG_U133A  208855_s_at  0.04  4.05e-1  4.60e-1  1.65  4.95e-43  1.00e-42
 HG_U133A  215188_at  0.01  9.35e-1  9.45e-1  -1.84  3.45e-26  5.49e-26
 HG_U133_Plus2  208854_s_at  0.37  3.51e-6  1.45e-5  0.73  9.91e-13  6.03e-12
 HG_U133_Plus2  208855_s_at  0.40  5.32e-9  3.37e-8  0.58  5.41e-18  5.99e-17
 HG_U133_Plus2  215188_at  -0.25  3.57e-1  4.47e-1  0.12  5.59e-1  6.16e-1
 Stanford  11803  0.34  3.36e-1  5.37e-1  0.44  1.44e-1  3.47e-1
 Stanford  20842  0.11  6.67e-1  8.04e-1  0.34  3.01e-1  5.42e-1
 Stanford  22195  0.20  5.04e-1  6.85e-1  0.43  1.71e-1  3.86e-1
 Agilent_HS_21.6K  10957  -0.07  4.08e-1  5.93e-1  0.12  1.45e-1  2.72e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  208854_s_at  0.20  3.43e-1  8.87e-1  -0.17  2.41e-1  1.00e+0
 HG_U133A  208855_s_at  0.30  1.22e-1  7.91e-1  -0.03  7.91e-1  1.00e+0
 HG_U133A  215188_at  -0.25  5.94e-1  9.51e-1  0.00  9.91e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 40473_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 208854_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 208855_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 215188_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 208854_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 208855_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 215188_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 11803    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 20842    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 22195    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 10957    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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