IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene ZIC2 Ensembl ENSG00000043355 Chromosome 13 Start 99432052 End 99437019
Description Zinc finger protein ZIC 2 (Zinc finger protein of the cerebellum 2) [Source:UniProtKB/Swiss-Prot;Acc:O95409]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 12873
     Entrez Gene : 7546
     UCSC : uc001von.2
     GeneCards : 12873
     RefSeq : NM_007129
     CCDS : CCDS9495.1
     Uniprot : O95409
     Interpro : O95409
     OMIM : 603073
     GeneTests : ZIC2
     CGAP : ZIC2
     PMID : 9771712

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  35554_f_at  0.33  3.97e-2  7.61e-2  0.96  7.34e-4  2.36e-3
 HG_U95  35555_r_at  -0.14  1.89e-1  2.79e-1  -0.15  3.42e-1  4.48e-1
 HG_U133_Plus2  223642_at  1.38  1.18e-5  4.45e-5  3.95  9.15e-28  3.22e-26
 Stanford  1323  0.71  1.23e-1  2.84e-1  1.41  8.72e-3  6.26e-2
 Stanford  6576  1.11  1.09e-2  6.85e-2  2.10  1.82e-4  4.18e-3
 Agilent_HS_21.6K  15150  0.31  3.85e-2  1.21e-1  0.44  1.23e-3  6.40e-3

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 35554_f_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 35555_r_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 223642_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 1323    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 6576    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 15150    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
zic2 glioblastoma Cotransfection of Zic1 and Zic2 expression vector and different APOE promoter-luciferase reporter constructs in U87 glioblastoma cell line showed that the three binding sites partially contributed to the trans-stimulation of the luciferase reporter. 11038359 Human
zic2 small cell lung cancer (sclc) Serological analysis of expression cDNA libraries (SEREX) derived from two small cell lung cancer (SCLC) cell lines using pooled sera of SCLC patients led to the isolation of 14 genes, including 4 SOX group B genes (SOX1, SOX2, SOX3, and SOX21) and ZIC2. 10760287 Human
zic2 small-cell lung carcinoma Frequency of SOX Group B (SOX1, 2, 3) and ZIC2 antibodies in Turkish patients with small cell lung carcinoma and their correlation with clinical parameters. 15880380 Human

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