IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene EVI2B Ensembl ENSG00000185862 Chromosome 17 Start 26654917 End 26665256
Description Protein EVI2B Precursor (Ecotropic viral integration site 2B protein homolog)(EVI-2B) [Source:UniProtKB/Swiss-Prot;Acc:P34910]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 3500
     Entrez Gene : 2124
     UCSC : uc002hgk.2
     GeneCards : 3500
     RefSeq : NM_006495
     CCDS : CCDS11266.1
     Uniprot : P34910
     Interpro : P34910
     OMIM : 158381
     GeneTests : EVI2B
     CGAP : EVI2B
     PMID : 1903357

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  40019_at  -1.20  9.75e-7  6.43e-6  -1.94  3.52e-9  3.50e-8
 HG_U133A  211742_s_at  -0.74  6.41e-14  3.19e-13  0.77  9.96e-13  1.30e-12
 HG_U133_Plus2  211742_s_at  -0.94  2.51e-12  2.45e-11  -1.82  5.66e-14  3.93e-13
 Stanford  13178  -1.55  9.20e-6  6.85e-4  -2.17  3.84e-6  2.47e-4
 Agilent_HS_21.6K  1813  -0.08  1.93e-1  3.66e-1  -0.13  9.50e-3  3.44e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  211742_s_at  0.97  1.14e-2  6.83e-1  -0.22  5.42e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 40019_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 211742_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 211742_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 13178    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 1813    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
evi2b neurofibroma Since patients with the NF1 large-deletion syndrome have a significantly increased risk of neurofibroma development and mental retardation, hemizygosity for genes from the deleted region around the neurofibromin locus (CYTOR4, FLJ12735, FLJ22729, HSA27219 11468690 Human
evi2b neurofibromatosis type 1 EVI2B, a gene lying in an intron of the neurofibromatosis type 1 (NF1) gene, is as the NF1 gene involved in differentiation of melanocytes and keratinocytes and is overexpressed in cells derived from NF1 neurofibromas. 10360836 Human
evi-2b tumors In the mouse the 5' exon of the homologous gene, Evi-2B, lies approximately 2.8 kb from the 3' end of Evi-2A, in the midst of a cluster of viral integration sites identified in retrovirus-induced myeloid tumors; thus, Evi-2B may function as an o 1903357 Mouse
evi-2b myeloid tumors In the mouse the 5' exon of the homologous gene, Evi-2B, lies approximately 2.8 kb from the 3' end of Evi-2A, in the midst of a cluster of viral integration sites identified in retrovirus-induced myeloid tumors; thus, Evi-2B may function as an o 1903357 Mouse
evi-2b oncogene In the mouse the 5' exon of the homologous gene, Evi-2B, lies approximately 2.8 kb from the 3' end of Evi-2A, in the midst of a cluster of viral integration sites identified in retrovirus-induced myeloid tumors; thus, Evi-2B may function as an o 1903357 Mouse

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