IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene CCL13 Ensembl ENSG00000181374 Chromosome 17 Start 29707584 End 29709741
Description C-C motif chemokine 13 Precursor (Small-inducible cytokine A13)(Monocyte chemoattractant protein 4)(Monocyte chemotactic protein 4)(MCP-4)(CK-beta-10)(NCC-1) [Contains C-C motif chemokine 13, long chain;C-C motif chemokine 13, medium chain;C-C motif chemokine 13, short chain] [Source:UniProtKB/Swiss-Prot;Acc:Q99616]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 10611
     Entrez Gene : 6357
     UCSC : uc002hic.2
     GeneCards : 10611
     RefSeq : NM_005408
     CCDS : CCDS11281.1
     Uniprot : Q99616
     Interpro : Q99616
     OMIM : 601391
     GeneTests : CCL13
     CGAP : CCL13
     PMID : 8661057

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  37454_at  -0.44  6.77e-2  1.19e-1  -1.25  3.25e-5  1.45e-4
 HG_U133A  206407_s_at  0.10  4.60e-1  5.14e-1  -0.85  4.92e-7  5.85e-7
 HG_U133A  216714_at  -0.48  6.90e-11  2.66e-10  1.79  1.41e-31  2.41e-31
 HG_U133_Plus2  206407_s_at  -0.53  1.69e-2  3.25e-2  -1.48  2.61e-9  1.06e-8
 HG_U133_Plus2  216714_at  -0.12  5.58e-1  6.41e-1  0.03  8.73e-1  8.96e-1
 Agilent_HS_21.6K  5146  -0.30  4.74e-2  1.40e-1  -0.48  1.31e-4  1.00e-3

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  206407_s_at  -0.21  6.45e-1  9.60e-1  -0.22  4.74e-1  1.00e+0
 HG_U133A  216714_at  -0.30  2.33e-1  8.46e-1  0.08  6.96e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 37454_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 206407_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 216714_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 206407_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 216714_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 5146    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
mcp-4 mouse lymphoma MCP-4 activated cell migration via either CCR2b or CCR3 in mouse lymphoma cells transfected with these chemokine receptors. 9062350 Mouse
ccl13 hl No or only very faint signals were obtained in HL for CXCL12, CCL7 and CCL8, but CXCL10, CCL5, CCL13, CCL17 and CCL22 were highly or differentially expressed in HL cell lines and tissues. 12115499 Human
mcp-4 nasal polyps (np) OBJECTIVE: To determine alterations in Th2 chemokines eotaxin and monocyte chemoattractant protein-4 (MCP-4), and cytokines interleukin-5 (IL-5) and interleukin-13 (IL-13), in nasal polyps (NP) after steroid treatment. 15523430 NA
monocyte chemoattractant protein-4 nasal polyps Alterations in eotaxin, monocyte chemoattractant protein-4, interleukin-5, and interleukin-13 after systemic steroid treatment for nasal polyps. 15523430 Human
monocyte chemoattractant protein-4 nasal polyps (np) OBJECTIVE: To determine alterations in Th2 chemokines eotaxin and monocyte chemoattractant protein-4 (MCP-4), and cytokines interleukin-5 (IL-5) and interleukin-13 (IL-13), in nasal polyps (NP) after steroid treatment. 15523430 NA

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