IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene LIG3 Ensembl ENSG00000005156 Chromosome 17 Start 30331651 End 30356201
Description DNA ligase 3 (EC 6.5.1.1)(DNA ligase III)(Polydeoxyribonucleotide synthase [ATP] 3) [Source:UniProtKB/Swiss-Prot;Acc:P49916]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 6600
     Entrez Gene : 3980
     UCSC : uc002hik.1
     GeneCards : 6600
     RefSeq : NM_013975
     CCDS : CCDS11284.2
     Uniprot : P49916
     Interpro : P49916
     OMIM : 600940
     GeneTests : LIG3
     CGAP : LIG3
     PMID : 7760816

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  1187_at  0.27  7.35e-2  1.28e-1  0.58  7.72e-3  1.84e-2
 HG_U95  1188_g_at  0.55  5.46e-3  1.39e-2  1.29  6.87e-6  3.59e-5
 HG_U95  41099_at  0.35  2.47e-3  6.97e-3  0.56  2.26e-4  8.26e-4
 HG_U133A  204123_at  0.85  2.86e-12  1.24e-11  3.76  4.78e-101  3.34e-100
 HG_U133A  207348_s_at  0.32  1.22e-6  3.12e-6  -0.12  2.28e-1  2.37e-1
 HG_U133_Plus2  1555169_at  0.36  3.35e-2  5.93e-2  0.53  9.17e-3  1.51e-2
 HG_U133_Plus2  204123_at  0.34  1.08e-2  2.19e-2  0.64  1.26e-6  3.65e-6
 HG_U133_Plus2  207348_s_at  0.48  6.22e-6  2.46e-5  0.91  4.48e-14  3.15e-13
 Stanford  10028  0.95  1.85e-6  2.16e-4  1.06  5.15e-4  8.76e-3
 Stanford  21708  1.27  1.70e-3  2.06e-2  1.14  5.55e-3  4.58e-2
 Agilent_HS_21.6K  10137  0.02  6.18e-1  7.66e-1  0.02  5.70e-1  7.06e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  204123_at  0.49  2.38e-1  8.49e-1  -0.30  2.49e-1  1.00e+0
 HG_U133A  207348_s_at  0.30  2.50e-1  8.52e-1  -0.37  6.41e-2  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 1187_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 1188_g_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 41099_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 204123_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 207348_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1555169_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 204123_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 207348_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 10028    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 21708    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 10137    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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