IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene RAD51L3 Ensembl ENSG00000185379 Chromosome 17 Start 30450929 End 30470948
Description DNA repair protein RAD51 homolog 4 (R51H3)(RAD51-like protein 3)(TRAD) [Source:UniProtKB/Swiss-Prot;Acc:O75771]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 9823
     Entrez Gene : 5892
     GeneCards : 9823
     RefSeq : NM_001142571
     CCDS : CCDS11287.1
     Uniprot : O94908
     Interpro : O94908
     OMIM : 602954
     GeneTests : RAD51L3
     CGAP : RAD51L3
     PMID : 9570954

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  37792_s_at  0.29  1.58e-2  3.46e-2  0.65  7.32e-4  2.35e-3
 HG_U95  37793_r_at  0.45  2.31e-3  6.56e-3  1.09  8.77e-8  6.79e-7
 HG_U133A  209965_s_at  0.11  3.87e-2  5.49e-2  1.61  1.42e-61  3.94e-61
 HG_U133A  37793_r_at  -0.04  4.70e-1  5.24e-1  0.55  5.99e-10  7.50e-10
 HG_U133_Plus2  209965_s_at  0.35  1.71e-3  4.22e-3  0.55  8.51e-6  2.20e-5
 HG_U133_Plus2  37793_r_at  0.67  7.63e-8  4.12e-7  1.11  7.54e-15  5.83e-14
 Stanford  5068  1.09  1.93e-4  5.06e-3  1.05  1.40e-3  1.76e-2
 Agilent_HS_21.6K  709  -0.01  7.50e-1  8.55e-1  0.00  9.34e-1  9.62e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  209965_s_at  -0.05  8.07e-1  9.83e-1  -0.06  6.75e-1  1.00e+0
 HG_U133A  37793_r_at  0.34  1.26e-1  7.93e-1  0.03  8.03e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 37792_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 37793_r_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 209965_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 37793_r_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 209965_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 37793_r_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 5068    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 709    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
rad51d high-risk breast cancer The variant E233G of the RAD51D gene could be a low-penetrance allele in high-risk breast cancer families without BRCA1/2 mutations. 15170666 Human
rad51d familial breast cancer The novel variant E233G in RAD51D is more highly represented in high-risk, site-specific, familial breast cancer cases that are not associated with the BRCA1/2 genes, with a frequency of 5.74% (n = 174) compared to a control population (n = 567) and anoth 15170666 Human
rad51d breast cancer The novel variant E233G in RAD51D is more highly represented in high-risk, site-specific, familial breast cancer cases that are not associated with the BRCA1/2 genes, with a frequency of 5.74% (n = 174) compared to a control population (n = 567) and anoth 15170666 Human

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