IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene GGNBP2 Ensembl ENSG00000005955 Chromosome 17 Start 31974917 End 32020387
Description Gametogenetin-binding protein 2 (Protein ZNF403)(Laryngeal carcinoma-related protein 1) [Source:UniProtKB/Swiss-Prot;Acc:Q9H3C7]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 19357
     Entrez Gene : 79893
     UCSC : uc002hnb.2
     GeneCards : 19357
     RefSeq : NM_024835
     CCDS : CCDS11314.1
     Uniprot : Q9H3C7
     Interpro : Q9H3C7
     OMIM : 612275
     GeneTests : GGNBP2
     CGAP : GGNBP2
     PMID : 11728448

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  218079_s_at  0.05  3.10e-1  3.63e-1  -6.27  1.32e-100  9.10e-100
 HG_U133_Plus2  1554419_x_at  0.14  4.26e-1  5.15e-1  0.31  1.06e-1  1.42e-1
 HG_U133_Plus2  218079_s_at  -0.01  8.67e-1  9.01e-1  0.07  2.05e-1  2.56e-1
 HG_U133_Plus2  233936_s_at  -0.48  3.35e-13  3.65e-12  -0.53  3.23e-10  1.46e-9
 HG_U133_Plus2  233937_at  -0.37  5.64e-3  1.23e-2  -0.62  5.21e-8  1.80e-7

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  218079_s_at  -0.09  6.87e-1  9.67e-1  0.17  2.89e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 218079_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1554419_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 218079_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 233936_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 233937_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
lcrg1 cancer By means of the mRNA differential display method we identified a cDNA, Laryngeal carcinoma related gene 1 (LCRG1) which has significantly reduced expression in 40% (12/30) of primary LCs and in 6 of 10 various cancer cell lines. 15145523 Human
laryngeal carcinoma related gene 1 cancer By means of the mRNA differential display method we identified a cDNA, Laryngeal carcinoma related gene 1 (LCRG1) which has significantly reduced expression in 40% (12/30) of primary LCs and in 6 of 10 various cancer cell lines. 15145523 Human
dif-3 tumor It has also been shown that DIF-1 and its derivative (DIF-3) suppress cell growth in mammalian tumor cells. 16023080 Human
dif-3 cancer In the present study, in order to assess the chemical structure-effect relationship of DIF derivatives and to develop useful agents for the study of both Dictyostelium development and cancer biology, we synthesized 28 analogues of DIF-1 and DIF-3 and inve 16023080 Human
dif-3 human leukemia In the present study, in order to assess the chemical structure-effect relationship of DIF derivatives and to develop useful agents for the study of both Dictyostelium development and cancer biology, we synthesized 28 analogues of DIF-1 and DIF-3 and inve 16023080 Human
lcrg1 laryngeal carcinoma [Analysis of differential proteins in laryngeal carcinoma cell line Hep-2 with transfection of LCRG1] BACKGROUND & OBJECTIVE: Laryngeal carcinoma-related gene 1 (LCRG1), a novel laryngeal carcinoma-related tumor suppressor gene, was cloned with mRNA diffe 16405744 Human
lcrg1 laryngeal carcinoma Previous researches showed LCRG1 might inhibit cell growth, proliferation, colony formation in soft agar, and tumorigenesis of laryngeal carcinoma cell line Hep-2. 16405744 Human
lcrg1 tumorigenesis Previous researches showed LCRG1 might inhibit cell growth, proliferation, colony formation in soft agar, and tumorigenesis of laryngeal carcinoma cell line Hep-2. 16405744 Human
lcrg1 tumor OBJECTIVES: A novel gene, laryngeal carcinoma-related gene 1 (LCRG1), had the characteristics of tumor-suppressor genes. 16467709 Human
lcrg1 laryngeal carcinoma OBJECTIVES: A novel gene, laryngeal carcinoma-related gene 1 (LCRG1), had the characteristics of tumor-suppressor genes. 16467709 Human
lcrg1 tumor Those identified proteins might contribute to the tumor-suppressive function of LCRG1. 16467709 Human
lcrg1 tumor CONCLUSIONS: We tentatively proposed those differentially expressed proteins were involved in the tumor-suppressive process related to LCRG1. 16467709 Human

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