IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene LHX1 Ensembl ENSG00000132130 Chromosome 17 Start 32368612 End 32374596
Description LIM/homeobox protein Lhx1 (LIM homeobox protein 1)(Homeobox protein Lim-1)(hLim-1) [Source:UniProtKB/Swiss-Prot;Acc:P48742]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 6593
     Entrez Gene : 3975
     UCSC : uc002hnh.1
     GeneCards : 6593
     RefSeq : NM_005568
     CCDS : CCDS11316.1
     Uniprot : P48742
     Interpro : P48742
     OMIM : 601999
     GeneTests : LHX1
     CGAP : LHX1
     PMID : 9212161

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  295_s_at  0.32  1.24e-1  1.97e-1  0.96  1.41e-3  4.19e-3
 HG_U95  35388_at  0.47  4.86e-3  1.25e-2  0.96  2.14e-4  7.86e-4
 HG_U133A  206230_at  0.50  4.78e-4  9.11e-4  2.80  4.68e-42  9.35e-42
 HG_U133_Plus2  206230_at  -0.09  5.89e-1  6.69e-1  -0.17  3.78e-1  4.39e-1
 Agilent_HS_21.6K  10520  -0.08  2.79e-1  4.65e-1  -0.04  5.74e-1  7.10e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  206230_at  -0.85  1.22e-2  6.83e-1  -0.03  8.98e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 295_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 35388_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 206230_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 206230_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 10520    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
lhx1 pancreatic cancers These genes include UCHL1 (methylated in 100% of 42 pancreatic cancers), NPTX2 (98%), SARP2 (95%), CLDN5 (93%), reprimo (86%), LHX1 (76%), WNT7A (71%), FOXE1 (69%), TJP2 (64%), CDH3 (19%), and ST14 (10%). 12839967 Human

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