IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene TADA2L Ensembl ENSG00000108264 Chromosome 17 Start 32841078 End 32911709
Description Transcriptional adapter 2-alpha (Transcriptional adapter 2-like)(ADA2-like protein) [Source:UniProtKB/Swiss-Prot;Acc:O75478]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 11531
     Entrez Gene : 6871
     GeneCards : 11531
     RefSeq : NM_001166105
     CCDS : CCDS11319.1
     Uniprot : O75478
     Interpro : O75478
     OMIM : 602276
     GeneTests : TADA2A
     CGAP : TADA2A
     PMID : 8552087

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  37789_at  -0.14  5.69e-1  6.65e-1  0.41  2.55e-1  3.54e-1
 HG_U133A  209938_at  0.06  3.09e-1  3.62e-1  1.80  2.14e-82  9.16e-82
 HG_U133A  210537_s_at  0.92  2.20e-13  1.04e-12  -0.11  2.52e-1  2.61e-1
 HG_U133_Plus2  209938_at  0.31  2.67e-3  6.28e-3  0.52  8.46e-6  2.19e-5
 HG_U133_Plus2  210537_s_at  0.61  2.13e-3  5.14e-3  0.66  1.86e-3  3.42e-3
 Agilent_HS_21.6K  5140  0.09  1.25e-1  2.75e-1  0.12  3.42e-2  9.28e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  209938_at  -0.09  6.49e-1  9.60e-1  -0.03  7.74e-1  1.00e+0
 HG_U133A  210537_s_at  -0.15  6.68e-1  9.63e-1  -0.37  1.64e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 37789_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 209938_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 210537_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 209938_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 210537_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 5140    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
ada2 leukemia Identification of ADA2 divided these leukemia cases into lymphoid and nonlymphoid types with no misclassifications (P = .0002; Fisher's exact test). 3140911 Human
ada2 acute nonlymphoblastic leukemia (anll) Acute nonlymphoblastic leukemia (ANLL) with a monocytic component tended to have a greater percentage of ADA2 than ANLL without a monocytic component. 3140911 Human
ada2 erythroleukemia We have established conditions for chromatographic fractionation of HATs and ADA2 from human K562 erythroleukemia cells. 9398325 Human
ada2 lung cancer Total adenosine deaminase (ADA) activity and its isozyme (ADA1 and ADA2) activities were measured in pleural effusions and serum samples from patients with tuberculosis and in those from patients with lung cancer as controls. 8656037 Human
ada2 lymphoma ADA2 activity was significantly elevated in the sera of patients with the acute, lymphoma, and chronic types of ATL (P < 0.001) compared with that in patients with smoldering ATL and HTLV-1 carriers. 8548545 Human
ada2 malignancy METHODS: Ascitic ADA(T), ADA1, ADA2 and IFN-gamma were prospectively evaluated in HIV-seronegative patients with tuberculous peritonitis (n = 17), HIV-seropositive patients with tuberculous peritonitis (n = 6) and in patients with cirrhosis (n = 22) and m 10333209 NA

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