IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene PIP4K2B Ensembl ENSG00000141720 Chromosome 17 Start 34175470 End 34209684
Description Phosphatidylinositol-5-phosphate 4-kinase type-2 beta (EC 2.7.1.149)(Phosphatidylinositol-5-phosphate 4-kinase type II beta)(1-phosphatidylinositol-5-phosphate 4-kinase 2-beta)(PtdIns(5)P-4-kinase isoform 2-beta)(PIP4KII-beta)(Diphosphoinositide kinase 2-beta) [Source:UniProtKB/Swiss-Prot;Acc:P78356]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 8998
     Entrez Gene : 8396
     UCSC : uc002hqs.2
     GeneCards : 8998
     RefSeq : NM_003559
     CCDS : CCDS11329.1
     Uniprot : P78356
     Interpro : P78356
     OMIM : 603261
     GeneTests : PIP4K2B
     CGAP : PIP4K2B
     PMID : 9038203

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  35741_at  -0.30  1.68e-4  6.48e-4  -0.57  2.04e-8  1.77e-7
 HG_U133A  201080_at  -0.43  1.33e-17  8.73e-17  -3.79  4.00e-80  1.63e-79
 HG_U133A  201081_s_at  0.44  2.90e-7  7.89e-7  1.37  1.92e-35  3.48e-35
 HG_U133_Plus2  1553047_at  0.41  9.06e-3  1.87e-2  1.16  2.63e-13  1.70e-12
 HG_U133_Plus2  1553048_a_at  0.53  1.22e-8  7.35e-8  0.58  2.71e-8  9.67e-8
 HG_U133_Plus2  201080_at  -0.02  7.19e-1  7.81e-1  -0.04  5.94e-1  6.48e-1
 HG_U133_Plus2  201081_s_at  1.09  3.96e-14  4.85e-13  1.48  7.75e-15  5.98e-14

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  201080_at  0.11  5.08e-1  9.30e-1  -0.18  1.01e-1  1.00e+0
 HG_U133A  201081_s_at  -0.27  4.30e-1  9.12e-1  0.11  4.93e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 35741_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 201080_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 201081_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1553047_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1553048_a_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 201080_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 201081_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
pip5k2b human tumors MLLT6, MLLT10 and LASP1 genes are fusion partners of MLL gene in hematological malignancies, while RNF110, PIP5K2B, LASP1 and BMI1 genes are amplified in human tumors. 15254754 Human
pip5k2b hematological malignancies MLLT6, MLLT10 and LASP1 genes are fusion partners of MLL gene in hematological malignancies, while RNF110, PIP5K2B, LASP1 and BMI1 genes are amplified in human tumors. 15254754 Human

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