IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene RPL23 Ensembl ENSG00000125691 Chromosome 17 Start 34257644 End 34263579
Description 60S ribosomal protein L23 (Ribosomal protein L17) [Source:UniProtKB/Swiss-Prot;Acc:P62829]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 10316
     Entrez Gene : 9349
     UCSC : uc002hqx.1
     GeneCards : 10316
     RefSeq : NM_000978
     CCDS : CCDS11330.1
     Uniprot : P62829
     Interpro : P62829
     OMIM : 603662
     GeneTests : RPL23
     CGAP : RPL23
     PMID : 1861993

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  32394_s_at  0.18  5.29e-2  9.67e-2  0.12  2.55e-1  3.54e-1
 HG_U133A  200888_s_at  0.06  1.18e-1  1.53e-1  -3.76  3.82e-165  2.46e-163
 HG_U133A  214744_s_at  0.05  6.91e-1  7.32e-1  1.99  8.31e-44  1.71e-43
 HG_U133_Plus2  200888_s_at  0.02  8.00e-1  8.48e-1  0.08  3.13e-1  3.73e-1
 HG_U133_Plus2  214744_s_at  -0.58  1.69e-4  5.16e-4  -1.04  1.09e-8  4.08e-8
 Stanford  23094  -0.16  5.25e-1  7.01e-1  0.08  8.05e-1  9.10e-1
 Agilent_HS_21.6K  219  0.34  1.46e-4  1.63e-3  0.36  6.68e-5  5.69e-4

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  200888_s_at  -0.24  2.81e-1  8.69e-1  0.07  5.87e-1  1.00e+0
 HG_U133A  214744_s_at  0.55  6.56e-2  7.28e-1  0.43  8.68e-2  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 32394_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 200888_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 214744_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 200888_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 214744_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 23094    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 219    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
rpl23 gastric cancer Ribosomal proteins (RP) S13 and RPL23 were previously identified as two upregulated genes in a multidrug-resistant gastric cancer cell line SGC7901/VCR compared to its parental cell SGC7901 by differential display PCR. 15149863 Human
rpl23 gastric cancer The aim of this study was to explore the roles of RPS13 and RPL23 in multidrug resistance (MDR) in gastric cancer cells. 15149863 Human
rpl23 gastric cancer Together, this work demonstrates that either RPS13 or RPL23 can promote MDR in gastric cancer cells by suppressing drug-induced apoptosis, and that RPL23 may also promote MDR in gastric cancer cells through regulation of glutathione S-transferase-mediated 15149863 Human

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