IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene CRKRS Ensembl ENSG00000167258 Chromosome 17 Start 34871265 End 34941095
Description Cell division cycle 2-related protein kinase 7 (CDC2-related protein kinase 7)(EC 2.7.11.22)(Cdc2-related kinase, arginine/serine-rich)(CrkRS) [Source:UniProtKB/Swiss-Prot;Acc:Q9NYV4]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 24224
     Entrez Gene : 51755
     UCSC : uc010cvv.2
     GeneCards : 24224
     RefSeq : NM_015083
     CCDS : CCDS11337.1
     Uniprot : Q9NYV4
     Interpro : Q9NYV4
     GeneTests : CDK12
     CGAP : CDK12
     PMID : 10048485

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  37772_at  0.73  1.38e-5  6.93e-5  0.58  2.06e-2  4.30e-2
 HG_U133A  213557_at  0.24  4.33e-5  9.42e-5  1.00  2.77e-38  5.23e-38
 HG_U133A  219226_at  0.22  3.76e-4  7.27e-4  1.67  1.51e-50  3.48e-50
 HG_U133_Plus2  213557_at  0.65  1.44e-8  8.62e-8  0.64  4.49e-6  1.21e-5
 HG_U133_Plus2  219226_at  0.26  7.37e-5  2.40e-4  0.31  5.80e-6  1.53e-5
 HG_U133_Plus2  225690_at  0.05  6.28e-1  7.03e-1  -0.34  1.01e-2  1.65e-2
 HG_U133_Plus2  225691_at  0.16  6.45e-2  1.05e-1  0.38  5.10e-5  1.19e-4
 HG_U133_Plus2  225694_at  -0.05  5.27e-1  6.12e-1  -0.17  7.25e-2  1.00e-1
 HG_U133_Plus2  225697_at  0.41  5.43e-8  2.99e-7  0.67  4.43e-15  3.51e-14
 Stanford  14046  0.45  4.65e-2  1.48e-1  0.51  8.86e-2  2.51e-1
 Stanford  15622  0.35  8.39e-2  2.20e-1  0.30  3.19e-1  5.59e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  213557_at  -0.11  5.75e-1  9.48e-1  -0.16  2.75e-1  1.00e+0
 HG_U133A  219226_at  -0.06  8.08e-1  9.83e-1  -0.04  7.79e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 37772_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 213557_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 219226_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 213557_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 219226_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 225690_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 225691_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 225694_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 225697_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 14046    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 15622    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
crk7 breast cancer We used a genetic association study design to determine if common genetic variation (frequency>or=5%) in a 400-kb region surrounding ERBB2 and containing the PPARBP, CRK7, NEUROD2, PPP1R1B, STARD3, TCAP, PNMT, CAB2, ERBB2, C17ORF37, GRB7 and ZNFN1A3 genes 17117180 Human

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