IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene NEUROD2 Ensembl ENSG00000171532 Chromosome 17 Start 35013548 End 35017701
Description Neurogenic differentiation factor 2 (NeuroD2)(NeuroD-related factor)(NDRF) [Source:UniProtKB/Swiss-Prot;Acc:Q15784]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 7763
     Entrez Gene : 4761
     UCSC : uc002hry.2
     GeneCards : 7763
     RefSeq : NM_006160
     CCDS : CCDS11338.1
     Uniprot : Q15784
     Interpro : Q15784
     OMIM : 601725
     GeneTests : NEUROD2
     CGAP : NEUROD2
     PMID : 9119405

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  38205_at  0.27  9.58e-3  2.26e-2  0.35  2.28e-2  4.71e-2
 HG_U133A  210271_at  -0.25  1.74e-6  4.38e-6  1.76  8.25e-46  1.75e-45
 HG_U133_Plus2  1552953_a_at  0.26  7.32e-2  1.17e-1  0.63  9.04e-5  2.03e-4
 HG_U133_Plus2  210271_at  0.05  7.52e-1  8.08e-1  0.62  3.01e-3  5.36e-3
 Agilent_HS_21.6K  21114  0.04  4.57e-1  6.38e-1  0.03  4.85e-1  6.36e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  210271_at  0.04  8.50e-1  9.88e-1  0.04  7.25e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 38205_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 210271_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1552953_a_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 210271_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 21114    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
neurod2 embryonal carcinoma Here we show that transient transfection of vectors expressing neuroD2, MASH1, ngn1 or related neural bHLH proteins, with their putative dimerization partner E12, can convert mouse P19 embryonal carcinoma cells into differentiated neurons. 10648228 Mouse
neurod2 cerebral primitive neuroectodermal tumors We analyzed expression of human NEUROD1, NEUROD2, NEUROD3, and ACHAETE SCUTE 1 (HASH1) in cerebellar and cerebral primitive neuroectodermal tumors (PNETs), gliomas, and cell lines derived from a variety of neuroectodermal tumors by Northern analysis and i 9270024 Human
neurod2 neuroectodermal tumors We analyzed expression of human NEUROD1, NEUROD2, NEUROD3, and ACHAETE SCUTE 1 (HASH1) in cerebellar and cerebral primitive neuroectodermal tumors (PNETs), gliomas, and cell lines derived from a variety of neuroectodermal tumors by Northern analysis and i 9270024 Human
neurod2 neuroblastoma Transient expression of NeuroD2, one of neural bHLH transcription factors, converted mouse N1E-115 neuroblastoma cells into differentiated neurons. 12443854 Mouse
neurod2 mouse neuroblastoma Mouse neuroblastoma cell line, N1E-115, was stably transfected with expression vector containing mouse NeuroD2 cDNA under HSP promoter. 12443854 Human
neurod2 gliomas We analyzed expression of human NEUROD1, NEUROD2, NEUROD3, and ACHAETE SCUTE 1 (HASH1) in cerebellar and cerebral primitive neuroectodermal tumors (PNETs), gliomas, and cell lines derived from a variety of neuroectodermal tumors by Northern analysis and i 9270024 Human
neurod2 medulloblastomas NEUROD1 was expressed in each of the 12 medulloblastoma specimens, whereas NEUROD2 and NEUROD3/neurogenin were expressed in partly overlapping subsets of medulloblastomas. 9270024 Human

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