IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene GSDMB Ensembl ENSG00000073605 Chromosome 17 Start 35314374 End 35328429
Description Gasdermin-B (Gasdermin-like protein) [Source:UniProtKB/Swiss-Prot;Acc:Q8TAX9]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 23690
     Entrez Gene : 55876
     UCSC : uc002hth.2
     GeneCards : 23690
     RefSeq : NM_001042471
     CCDS : CCDS11354.1
     Uniprot : Q8TAX9
     Interpro : Q8TAX9
     OMIM : 611221
     GeneTests : GSDMB
     CGAP : GSDMB
     PMID : 12883658

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  215659_at  0.01  9.32e-1  9.42e-1  0.95  5.33e-16  7.31e-16
 HG_U133A  219233_s_at  1.15  3.49e-19  2.59e-18  0.79  1.06e-9  1.33e-9
 HG_U133_Plus2  215659_at  -0.37  1.12e-1  1.69e-1  -0.88  4.34e-5  1.02e-4
 HG_U133_Plus2  219233_s_at  0.96  1.24e-10  9.74e-10  0.58  7.28e-6  1.90e-5
 HG_U133_Plus2  240701_at  -0.26  6.78e-2  1.10e-1  -0.50  3.73e-3  6.54e-3

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  215659_at  -0.11  6.92e-1  9.67e-1  0.24  4.34e-1  1.00e+0
 HG_U133A  219233_s_at  -1.08  5.03e-3  6.53e-1  0.14  6.71e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 215659_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 219233_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 215659_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 219233_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 240701_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
gsdml cancer Because DFNA5 and MLZE are cancer-associated genes, DFNA5L, GSDM, and GSDML are predicted cancer associated genes. 15289881 Human

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