IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene KRT35 Ensembl ENSG00000197079 Chromosome 17 Start 36886467 End 36890918
Description Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5)(Keratin-35)(K35) [Source:UniProtKB/Swiss-Prot;Acc:Q92764]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 6453
     Entrez Gene : 3886
     UCSC : uc002hws.2
     GeneCards : 6453
     RefSeq : NM_002280
     CCDS : CCDS11394.2
     Uniprot : Q92764
     Interpro : Q92764
     OMIM : 602764
     GeneTests : KRT35
     CGAP : KRT35
     PMID : 8823373

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  34627_at  0.05  7.58e-1  8.24e-1  0.24  2.89e-1  3.92e-1
 HG_U133A  216921_s_at  -0.33  4.02e-3  6.70e-3  3.28  8.81e-66  2.65e-65
 HG_U133_Plus2  216921_s_at  0.04  8.31e-1  8.73e-1  0.17  4.28e-1  4.89e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  216921_s_at  0.04  9.19e-1  9.95e-1  0.26  2.74e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 34627_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 216921_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 216921_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
hha5 basal-cell carcinomas METHODS: We performed immunohistochemistry on paraffin sections of formalin-fixed pilomatrixomas (40), trichoepitheliomas (10), trichoblastomas (10), desmoplastic trichoepitheliomas (10) and basal cell carcinomas (10), using antibodies against type I hair 11359384 NA
hha5 tumors All type I and II hair keratins tested, (especially hHa1, hHa5, and hHa8) remained negative in all tumors examined. 11801790 Human
ha-v hepatoma In this study, we demonstrate that transfection of rat hepatoma FTO 2B cells, a cell line that is not infectable by hepatitis B virus (HBV) and does not express hA-V, with a construct containing the hA-V gene, resulted in hA-V expressing cells susceptible 9918938 NA
ha-v hepatoma In contrast to primary cultures of human hepatocytes and FTO 9.1 cells, primary rat and mouse hepatocytes, as well as rat hepatoma cell lines that do not express hA-V, are not susceptible to HBV infection. 9918938 Rat

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