IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene EZH1 Ensembl ENSG00000108799 Chromosome 17 Start 38105820 End 38150574
Description Histone-lysine N-methyltransferase EZH1 (EC 2.1.1.43)(Enhancer of zeste homolog 1)(ENX-2) [Source:UniProtKB/Swiss-Prot;Acc:Q92800]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 3526
     Entrez Gene : 2145
     UCSC : uc002iaz.2
     GeneCards : 3526
     RefSeq : NM_001991
     CCDS : CCDS32659.1
     Uniprot : Q53XP3
     Interpro : Q53XP3
     OMIM : 601674
     GeneTests : EZH1
     CGAP : EZH1
     PMID : 8921387

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  32259_at  -0.40  1.62e-7  1.27e-6  -0.40  9.69e-5  3.88e-4
 HG_U133A  203249_at  -1.18  8.69e-20  6.70e-19  0.14  2.47e-1  2.56e-1
 HG_U133A  211310_at  0.09  5.95e-1  6.43e-1  2.18  3.44e-39  6.58e-39
 HG_U133A  32259_at  -0.73  5.43e-37  1.27e-35  -3.16  3.82e-79  1.52e-78
 HG_U133_Plus2  203249_at  -0.72  1.07e-11  9.61e-11  -1.25  5.65e-15  4.42e-14
 HG_U133_Plus2  211310_at  0.16  5.02e-1  5.89e-1  -0.45  6.69e-2  9.34e-2
 HG_U133_Plus2  239197_s_at  0.60  1.72e-8  1.01e-7  0.99  8.08e-13  4.97e-12
 HG_U133_Plus2  239198_at  0.27  4.78e-2  8.10e-2  0.64  3.55e-5  8.44e-5
 HG_U133_Plus2  32259_at  -0.53  1.10e-16  1.81e-15  -0.94  3.85e-23  7.71e-22
 Agilent_HS_21.6K  4728  0.02  5.46e-1  7.12e-1  -0.00  9.30e-1  9.60e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  203249_at  0.46  3.44e-1  8.87e-1  0.59  6.45e-2  1.00e+0
 HG_U133A  211310_at  -0.71  2.53e-1  8.54e-1  -0.44  3.11e-1  1.00e+0
 HG_U133A  32259_at  0.10  6.24e-1  9.55e-1  0.16  1.26e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 32259_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 203249_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 211310_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 32259_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 203249_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 211310_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 239197_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 239198_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 32259_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 4728    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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