IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene IFI35 Ensembl ENSG00000068079 Chromosome 17 Start 38412351 End 38419998
Description Interferon-induced 35 kDa protein (IFP 35) [Source:UniProtKB/Swiss-Prot;Acc:P80217]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :
     HGNC : 5399
     Entrez Gene : 3430
     UCSC : uc010whj.1
     GeneCards : 5399
     RefSeq : NM_005533
     CCDS : CCDS11450.1
     Uniprot : P80217
     Interpro : P80217
     OMIM : 600735
     GeneTests : IFI35
     CGAP : IFI35

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  464_s_at  -0.32  1.41e-2  3.15e-2  -0.77  4.25e-8  3.49e-7
 HG_U95  626_s_at  -0.30  2.36e-2  4.87e-2  -0.67  1.67e-5  8.00e-5
 HG_U133A  209417_s_at  0.24  3.76e-3  6.30e-3  0.81  4.03e-20  5.85e-20
 HG_U133_Plus2  209417_s_at  0.20  3.31e-2  5.87e-2  -0.18  1.05e-1  1.41e-1
 Stanford  17921  0.26  4.93e-1  6.75e-1  -0.12  7.15e-1  8.59e-1
 Agilent_HS_21.6K  14027  -0.06  2.25e-2  8.27e-2  -0.07  3.52e-2  9.48e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  209417_s_at  0.15  4.39e-1  9.13e-1  -0.23  2.15e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 464_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 626_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 209417_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 209417_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 17921    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 14027    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
ifp35 tumor Importantly, similar to Nmi and contrast to IFP35, CKIP-1 inhibits tumor cell growth and Akt-mediated cell survival. 17197158 Human
ifi35 ctcl RESULTS: Expression of various IFN-alpha-inducible genes (e.g., CIG5, G1P2, OASL, IFIT1, STAT1, IFI35, OAS1, ISG20, MxA, and IRF7), the so-called IFN-alpha signature, was increased similarly in both sBCC and CTCL lesions after imiquimod treatment. 16077073 Human

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