IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene VAT1 Ensembl ENSG00000108828 Chromosome 17 Start 38420148 End 38427985
Description Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-) [Source:UniProtKB/Swiss-Prot;Acc:Q99536]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 16919
     Entrez Gene : 10493
     UCSC : uc002icm.1
     GeneCards : 16919
     RefSeq : NM_006373
     CCDS : CCDS11451.1
     Uniprot : Q99536
     Interpro : Q99536
     OMIM : 604631
     GeneTests : VAT1
     CGAP : VAT1
     PMID : 7774926

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  40147_at  -0.33  1.03e-4  4.18e-4  -0.62  1.39e-6  8.41e-6
 HG_U95  605_at  -0.63  4.97e-9  5.38e-8  -0.79  3.80e-8  3.15e-7
 HG_U95  625_at  -0.37  2.98e-3  8.22e-3  -0.41  2.25e-3  6.28e-3
 HG_U133A  208626_s_at  -1.12  3.17e-39  8.34e-38  -1.45  1.74e-52  4.13e-52
 HG_U133_Plus2  208626_s_at  -0.58  8.46e-8  4.54e-7  -0.53  6.65e-5  1.52e-4
 Agilent_HS_21.6K  15980  -0.34  2.85e-8  1.11e-6  -0.44  2.75e-11  1.90e-9

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  208626_s_at  -0.00  9.98e-1  1.00e+0  -0.18  2.74e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 40147_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 605_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 625_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 208626_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 208626_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 15980    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
vat-1 ehrlich ascites tumor Mammalian protein homologous to VAT-1 of Torpedo californica: isolation from Ehrlich ascites tumor cells, biochemical characterization, and organization of its gene. 9581869 Human
vat-1 breast cancer Recently, interest has focused on the human gene encoding the putative protein homologous to VAT-1, the major protein of the synaptic vesicles of the electric organ of the Pacific electric ray Torpedo californica, after it has been localized on chromosome 9581869 Human
vat-1 ehrlich ascites tumor This VAT-1 homolog was isolated from a murine breast cancer cell line (Ehrlich ascites tumor) and identified by sequencing of cleavage peptides. 9581869 Human
vat-1 murine breast cancer This VAT-1 homolog was isolated from a murine breast cancer cell line (Ehrlich ascites tumor) and identified by sequencing of cleavage peptides. 9581869 Human
vat-1 ehrlich ascites tumor The isolated VAT-1 homolog protein displays an ATPase activity and exists in two isoforms with isoelectric points of 5.7 and 5.8. cDNA was prepared from Ehrlich ascites tumor cells, and the murine VAT-1 homolog sequence was amplified by polymerase chain r 9581869 Human
vat-1 breast cancer By Northern blots, the size of the VAT-1 homolog mRNA in both murine and human (T47D) breast cancer cells was determined to be 2.8 kb. 9581869 Human

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