IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene RND2 Ensembl ENSG00000108830 Chromosome 17 Start 38430784 End 38437583
Description Rho-related GTP-binding protein RhoN Precursor (Rho family GTPase 2)(Rnd2)(Rho7) [Source:UniProtKB/Swiss-Prot;Acc:P52198]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :
     HGNC : 18315
     Entrez Gene : 8153
     UCSC : uc002icn.2
     GeneCards : 18315
     RefSeq : NM_005440
     CCDS : CCDS11452.1
     Uniprot : P52198
     Interpro : P52198
     OMIM : 601555
     GeneTests : RND2
     CGAP : RND2

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  41082_at  0.37  8.95e-2  1.50e-1  0.45  9.39e-2  1.56e-1
 HG_U95  606_at  0.31  1.13e-1  1.83e-1  0.27  4.09e-1  5.15e-1
 HG_U95  644_at  -0.29  1.06e-1  1.73e-1  -0.05  8.39e-1  8.86e-1
 HG_U133A  213467_at  0.87  7.88e-9  2.51e-8  -1.89  4.35e-38  8.20e-38
 HG_U133A  214393_at  0.11  4.13e-1  4.69e-1  5.69  4.69e-119  5.53e-118
 HG_U133_Plus2  213467_at  0.62  1.08e-4  3.41e-4  1.25  3.61e-11  1.82e-10
 HG_U133_Plus2  214393_at  0.03  8.63e-1  8.98e-1  0.70  3.10e-4  6.44e-4

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  213467_at  0.85  1.09e-1  7.80e-1  -0.16  7.29e-1  1.00e+0
 HG_U133A  214393_at  -0.29  4.91e-1  9.26e-1  -0.29  2.67e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 41082_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 606_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 644_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 213467_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 214393_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 213467_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 214393_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
rho-7 tumor However, the level of Rho-A and -B and rho-7 and -8 was found to be similar in tumor and normal tissues. 14695145 Human
rho7 astrocytomas In oligodendrogliomas, 40 genes showed on average higher expression (at least a two-fold increase) than in astrocytomas, including DES, TDGF1, TGF-beta, GABA-BR1A, Histone H4, CDKN1A, PCDH43, Rho7 and Jun-D, while 39 genes were expressed at lower levels ( 15208679 Human
rho7 oligodendrogliomas In oligodendrogliomas, 40 genes showed on average higher expression (at least a two-fold increase) than in astrocytomas, including DES, TDGF1, TGF-beta, GABA-BR1A, Histone H4, CDKN1A, PCDH43, Rho7 and Jun-D, while 39 genes were expressed at lower levels ( 15208679 Human

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