IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene NBR2 Ensembl ENSG00000198496 Chromosome 17 Start 38531135 End 38549760
Description Protein NBR2 (Next to BRCA1 gene 2 protein) [Source:UniProtKB/Swiss-Prot;Acc:O15453]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 20691
     Entrez Gene : 10230
     UCSC : uc002idf.2
     GeneCards : 20691
     RefSeq : NR_003108
     Uniprot : O15453
     Interpro : O15453
     GeneTests : NBR2
     CGAP : NBR2
     PMID : 9215675

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  35383_at  0.58  7.63e-4  2.47e-3  0.52  9.12e-3  2.13e-2
 HG_U133A  207631_at  0.79  8.50e-9  2.70e-8  3.22  2.50e-26  3.98e-26
 HG_U133_Plus2  1553992_s_at  0.52  3.35e-4  9.61e-4  0.09  6.32e-1  6.84e-1
 HG_U133_Plus2  207631_at  1.05  1.40e-9  9.54e-9  0.56  6.33e-3  1.07e-2
 Stanford  4293  0.27  2.77e-1  4.78e-1  0.35  3.04e-1  5.44e-1
 Stanford  23568  0.67  3.56e-2  1.39e-1  0.26  5.90e-1  7.79e-1
 Agilent_HS_21.6K  19250  -0.06  1.18e-2  5.17e-2  -0.04  1.25e-1  2.45e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  207631_at  -0.86  9.42e-2  7.69e-1  0.45  2.47e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 35383_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 207631_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1553992_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 207631_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 4293    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 23568    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 19250    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
nbr2 human breast cancer Expression of BRCA1, NBR1 and NBR2 genes in human breast cancer cells. 11508855 Human
nbr2 human breast cancer Because of this intimate contact and because of our previous observation of a quasi-reciprocal expression pattern of Brca1 and Nbr1 in mouse spermatogenesis, we estimated here the relative mRNA expression of BRCA1, NBR1 (next-to-BRCA1) and NBR2 genes in a 11508855 Human
nbr2 primary breast cancer The expression of NBR2 differed, being increased in three permanent tumour cell lines and slightly decreased in all primary breast cancer cell cultures. 11508855 Human
nbr2 tumour The expression of NBR2 differed, being increased in three permanent tumour cell lines and slightly decreased in all primary breast cancer cell cultures. 11508855 Human
nbr2 cancers Single-strand conformation polymorphism (SSCP) analysis of the NBR2 gene failed to identify any mutations in either breast or ovarian cancer, suggesting that if the NBR2 gene is involved in the development of these cancers, other mechanisms for tumorigene 9215675 Human
nbr2 ovarian cancer Single-strand conformation polymorphism (SSCP) analysis of the NBR2 gene failed to identify any mutations in either breast or ovarian cancer, suggesting that if the NBR2 gene is involved in the development of these cancers, other mechanisms for tumorigene 9215675 Human

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