IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene ARL4D Ensembl ENSG00000175906 Chromosome 17 Start 38831879 End 38834029
Description ADP-ribosylation factor-like protein 4D (ADP-ribosylation factor-like protein 4L) [Source:UniProtKB/Swiss-Prot;Acc:P49703]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 656
     Entrez Gene : 379
     UCSC : uc002idt.2
     GeneCards : 656
     RefSeq : NM_001661
     CCDS : CCDS11463.1
     Uniprot : P49703
     Interpro : P49703
     OMIM : 600732
     GeneTests : ARL4D
     CGAP : ARL4D
     PMID : 7590735

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  41774_at  0.24  3.07e-1  4.12e-1  0.60  6.70e-2  1.17e-1
 HG_U133A  203586_s_at  0.19  4.07e-2  5.75e-2  2.20  2.63e-65  7.82e-65
 HG_U133A  203587_at  -0.52  1.81e-4  3.64e-4  3.96  2.97e-85  1.37e-84
 HG_U133_Plus2  203586_s_at  0.23  4.88e-2  8.25e-2  1.51  1.09e-24  2.59e-23
 HG_U133_Plus2  203587_at  0.01  9.43e-1  9.59e-1  0.39  8.65e-2  1.18e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  203586_s_at  -0.17  5.19e-1  9.34e-1  -0.08  6.85e-1  1.00e+0
 HG_U133A  203587_at  0.13  7.75e-1  9.78e-1  0.11  7.49e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 41774_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 203586_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 203587_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 203586_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 203587_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
adp-ribosylation factor 4-like brain tumors Recognition of ADP-ribosylation factor 4-like by HLA-A2-restricted and tumor-reactive cytotoxic T lymphocytes from patients with brain tumors. 12472661 Human
arf4l brain tumors Two peptides, ARF4L 15-24 and ARF4L 69-77, possessed the ability to induce HLA-A2-restricted and tumor-reactive CTLs from peripheral blood mononuclear cells of patients with brain tumors. 12472661 Human
arf4l brain tumors These results indicate that these two ARF4L peptides could be targets for immunotherapy of HLA-A2+ patients with brain tumors. 12472661 Human

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