IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene DUSP3 Ensembl ENSG00000108861 Chromosome 17 Start 39199016 End 39211872
Description Dual specificity protein phosphatase 3 (EC 3.1.3.48)(EC 3.1.3.16)(Dual specificity protein phosphatase VHR) [Source:UniProtKB/Swiss-Prot;Acc:P51452]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 3069
     Entrez Gene : 1845
     UCSC : uc002ied.3
     GeneCards : 3069
     RefSeq : NM_004090
     CCDS : CCDS11469.1
     Uniprot : P51452
     Interpro : P51452
     OMIM : 600183
     GeneTests : DUSP3
     CGAP : DUSP3
     PMID : 7829094

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  275_at  -0.67  1.55e-3  4.64e-3  -1.43  4.36e-6  2.39e-5
 HG_U95  41225_at  -0.75  3.74e-15  1.22e-13  -1.16  7.31e-15  2.26e-13
 HG_U95  41226_at  0.02  8.03e-1  8.60e-1  -0.27  1.08e-1  1.76e-1
 HG_U133A  201536_at  -0.87  1.10e-46  4.53e-45  -2.19  1.09e-89  5.62e-89
 HG_U133A  201537_s_at  0.05  3.51e-1  4.05e-1  3.25  8.40e-114  8.40e-113
 HG_U133A  201538_s_at  0.36  1.10e-5  2.54e-5  3.16  1.16e-104  8.97e-104
 HG_U133_Plus2  201536_at  -0.84  5.83e-27  2.88e-25  -1.09  4.22e-29  1.73e-27
 HG_U133_Plus2  201537_s_at  -0.18  6.33e-2  1.03e-1  -0.12  3.04e-1  3.63e-1
 HG_U133_Plus2  201538_s_at  -0.06  7.22e-1  7.84e-1  -0.22  1.36e-1  1.77e-1
 Stanford  9413  -0.31  2.21e-1  4.15e-1  -0.96  9.21e-3  6.51e-2
 Agilent_HS_21.6K  18611  -0.26  4.25e-12  4.46e-10  -0.29  1.20e-8  3.55e-7

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  201536_at  0.06  6.94e-1  9.67e-1  -0.11  4.56e-1  1.00e+0
 HG_U133A  201537_s_at  0.16  4.82e-1  9.26e-1  -0.24  2.35e-1  1.00e+0
 HG_U133A  201538_s_at  0.27  3.94e-1  8.97e-1  -0.18  1.88e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 275_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 41225_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 41226_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 201536_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 201537_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 201538_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 201536_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 201537_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 201538_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 9413    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 18611    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
vhr breast and ovarian cancer The VH1-related human protein (VHR) gene was localized to human chromosome 17q21 in a region thought to contain the BRCA1 locus, a locus that confers susceptibility to breast and ovarian cancer. 7829067 Human
vhr familial breast cancer To test this possibility, the VHR coding sequence was screened in individuals with familial breast cancer and in sporadic breast tumor and breast cancer cell lines. 7829067 Human
vhr breast cancer To test this possibility, the VHR coding sequence was screened in individuals with familial breast cancer and in sporadic breast tumor and breast cancer cell lines. 7829067 Human
vhr breast tumor To test this possibility, the VHR coding sequence was screened in individuals with familial breast cancer and in sporadic breast tumor and breast cancer cell lines. 7829067 Human
vhr acute lymphoblastic leukemia (all) PURPOSE: The optimal postremission therapy for children with very high-risk (VHR) acute lymphoblastic leukemia (ALL) is not well established. 17194902 Human

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