IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene MPP2 Ensembl ENSG00000108852 Chromosome 17 Start 39308253 End 39340639
Description MAGUK p55 subfamily member 2 (Protein MPP2)(Discs large homolog 2) [Source:UniProtKB/Swiss-Prot;Acc:Q14168]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 7220
     Entrez Gene : 4355
     UCSC : uc002ieo.1
     GeneCards : 7220
     RefSeq : NM_005374
     CCDS : CCDS11471.1
     Uniprot : Q14168
     Interpro : Q14168
     OMIM : 600723
     GeneTests : MPP2
     CGAP : MPP2
     PMID : 7590743

< Top >


Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  34655_at  0.30  1.64e-3  4.86e-3  0.34  9.40e-3  2.19e-2
 HG_U95  34656_at  0.19  2.45e-1  3.44e-1  0.45  7.00e-2  1.22e-1
 HG_U133A  207984_s_at  -0.35  2.26e-7  6.22e-7  -2.40  1.77e-61  4.92e-61
 HG_U133A  213270_at  0.04  5.17e-1  5.70e-1  1.47  8.13e-52  1.91e-51
 HG_U133_Plus2  207984_s_at  0.41  1.14e-2  2.30e-2  1.33  1.11e-12  6.71e-12
 HG_U133_Plus2  213270_at  0.20  5.77e-2  9.54e-2  0.82  2.00e-12  1.18e-11
 Stanford  13323  0.48  8.51e-2  2.22e-1  0.87  3.20e-3  3.11e-2
 Agilent_HS_21.6K  10813  -0.10  5.03e-2  1.46e-1  -0.12  4.00e-2  1.05e-1

< Top >


Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  207984_s_at  0.05  7.71e-1  9.77e-1  0.08  5.55e-1  1.00e+0
 HG_U133A  213270_at  0.34  1.11e-1  7.80e-1  0.04  8.01e-1  1.00e+0

< Top >


Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 34655_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 34656_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 207984_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 213270_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 207984_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 213270_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 13323    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 10813    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

< Top >


Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
dlg2 tumor A gene (DLG2) located at 17q12-q21 encodes a new homologue of the Drosophila tumor suppressor dIg-A. 7590743 Human
dlg2 breast and ovarian cancer Since allelic loss has been reported in the 17q12-q21 region in breast and ovarian cancer and it appears that BRCA1 is not the target of the losses, we looked for somatic alterations in DLG2 in sporadic breast tumors. 7590743 Human
dlg2 breast tumors Since allelic loss has been reported in the 17q12-q21 region in breast and ovarian cancer and it appears that BRCA1 is not the target of the losses, we looked for somatic alterations in DLG2 in sporadic breast tumors. 7590743 Human
dlg2 sporadic breast cancer No evidence for mutation was found, making it unlikely that DLG2 is involved in sporadic breast cancer. 7590743 Human

< Top >


Download all image files.
Save all PNG files.    Save all PDF files.    Save all PS files.