IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene PPY Ensembl ENSG00000108849 Chromosome 17 Start 39373698 End 39375359
Description Pancreatic prohormone Precursor (Pancreatic polypeptide)(PP)(Obinepitide) [Contains Pancreatic hormone(PH);Pancreatic icosapeptide(PI)] [Source:UniProtKB/Swiss-Prot;Acc:P01298]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 9327
     Entrez Gene : 5539
     UCSC : uc002iep.2
     GeneCards : 9327
     RefSeq : NM_002722
     CCDS : CCDS11472.1
     Uniprot : P01298
     Interpro : P01298
     OMIM : 167780
     GeneTests : PPY
     CGAP : PPY
     PMID : 3753985

< Top >


Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  32339_at  -0.27  1.44e-1  2.24e-1  -0.74  2.77e-3  7.53e-3
 HG_U133A  210670_at  -0.04  5.97e-1  6.45e-1  3.48  9.70e-115  9.95e-114
 HG_U133_Plus2  210670_at  0.98  9.50e-7  4.30e-6  1.55  1.22e-11  6.51e-11
 Stanford  12626  0.47  2.35e-1  4.33e-1  0.30  6.22e-1  8.01e-1
 Agilent_HS_21.6K  2169  0.02  4.36e-1  6.19e-1  0.02  3.35e-1  4.94e-1

< Top >


Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  210670_at  0.42  7.15e-2  7.34e-1  -0.12  4.77e-1  1.00e+0

< Top >


Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 32339_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 210670_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 210670_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 12626    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 2169    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

< Top >


Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
pancreatic polypeptide tumourbearing Immunoreactive pancreatic polypeptide levels in the head of the pancreas were reduced by 70%, but the relatively low levels of peptide in the pancreatic tail were similar in tumour-bearing and control rats. 2987070 Human
pancreatic polypeptide multiple endocrine neoplasia type 1 BACKGROUND: The diagnostic value of the determination of the serum pancreatic polypeptide (PP) and gastrin concentrations after a standard meal for early diagnosis of patients with multiple endocrine neoplasia type 1 (MEN 1) is controversial. 12108524 Human
pancreatic polypeptide pituitary tumor Since the initial testing, the family has been confirmed to be a MEN-1 family as the mother has developed abdominal pain and an elevated serum pancreatic polypeptide and the younger brother an anterior pituitary tumor and recurrent HPT. 12016470 Human
pancreatic polypeptide metastases To clarify whether scattered endocrine cells in pancreatic ductal adenocarcinoma are neoplastic or not, we immunohistochemically studied 29 cases of invasive pancreatic ductal adenocarcinomas, 17 with metastases, for chromogranin A, insulin, glucagon, pan 12242521 Human
pancreatic polypeptide pancreatic ductal adenocarcinomas To clarify whether scattered endocrine cells in pancreatic ductal adenocarcinoma are neoplastic or not, we immunohistochemically studied 29 cases of invasive pancreatic ductal adenocarcinomas, 17 with metastases, for chromogranin A, insulin, glucagon, pan 12242521 Human
pancreatic polypeptide pancreatic ductal adenocarcinoma To clarify whether scattered endocrine cells in pancreatic ductal adenocarcinoma are neoplastic or not, we immunohistochemically studied 29 cases of invasive pancreatic ductal adenocarcinomas, 17 with metastases, for chromogranin A, insulin, glucagon, pan 12242521 Human
pancreatic polypeptide cyst The immunohistochemical study showed that endocrine cells were present within the cyst epithelium, positive for chromogranin, synaptophysin, bombesin, and calcitonin, and negative for serotonin, somatostatin, glucagon, insulin, gastrin, and pancreatic pol 10685641 Human
pancreatic polypeptide prolactinoma In the latter case, abnormal release of hypothalamic dopamine, GABA, or brain-gut peptides (such as cholecystokinin, vasoactive intestinal polypeptide, galanin, angiotensin, opioid peptide, gastrin, gastrin-releasing peptide, pancreatic polypeptide, and a 10686432 Human
pancreatic polypeptide tumor Therefore, general tumor markers such as chromogranin A, pancreatic polypeptide, serum neuron-specific enolase and subunits of glycoprotein hormones have been used for screening purposes in patients without distinct clinical hormone-related symptoms. 10940685 Human
pancreatic polypeptide neuroendocrine carcinoma Pancreatic polypeptide hypersecretion associated with a neuroendocrine carcinoma of the gallbladder. 9892273 Human
pancreatic polypeptide residual tumor Earlier measurement of serum hormone levels and identification of high pancreatic polypeptide levels may have suggested the presence of residual tumor and led to closer follow-up, imaging studies, and therapy. 9892273 Human
pancreatic polypeptide multiple endocrine neoplasia One hundred four endocrine tumors found in the body and tail of the pancreas of a patient with the Zollinger-Ellison syndrome (ZES) and multiple endocrine neoplasia (MEN-I) were investigated by immunohistochemistry for insulin, glucagon, somatostatin, pan 2895680 Human
pancreatic polypeptide benign neoplasms This "granular" staining was predominantly associated with benign neoplasms and with the tumoral production of glucagon and pancreatic polypeptide (PP), while it was absent or inconsistent in most insulin-secreting tumors. 2840831 Human
pancreatic polypeptide carcinomas RESULTS--The immunoreactivity of the carcinomas and surrounding mucosa by the labeled streptavidin-biotin complex method for polyclonal rabbit antibody against human vasoactive intestinal polypeptide, pancreatic polypeptide, and somatostatin was 61%, 59%, 8651858 Human
pancreatic polypeptide small-cell carcinomas Sections of 29 small cell carcinomas from oesophagus, stomach, larynx, colon and urinary bladder were immunostained using antisera to protein gene product 9.5 (PGP 9.5), neuron-specific enolase (NSE), cytokeratin, leucocyte common antigen and peptides inc 3027289 Human
pancreatic polypeptide glucagonoma We present a patient with metastasizing glucagonoma and highly elevated plasma levels of glucagon and pancreatic polypeptide. 2998160 Human
pancreatic polypeptide parathyroid tumors Taken together with our prior findings of gastrin and pancreatic polypeptide in some human parathyroid glands, we postulate that human parathyroid tumors contain neural crest elements. 2866589 Human
pancreatic polypeptide somatostatinoma syndrome Somatostatinoma syndrome accompanied by overproduction of pancreatic polypeptide. 6144197 Human
pancreatic polypeptide polyp Hamartomatous polyp in adult oxyntic mucosa, hyperplastic oxyntic mucosa in Menetrier's disease and atrophic oxyntic mucosa in a remnant stomach with cancer showed scattered glucagon-glicentin cells, but few or no cells containing bovine pancreatic p 6207142 Human
pancreatic polypeptide metaplasia Goblet cell metaplasia was closely related to the occurrence of endocrine cells that showed argentaffinity, argyrophilia, or immunoreactive gastrin, somatostatin, pancreatic polypeptide, or motilin. 6548369 Human
pancreatic polypeptide pituitary adenoma The absence of radiologic signs of a pituitary adenoma in conjunction with elevated plasma levels of pancreatic polypeptide, glucagon, somatostatin, as well as growth hormone (GH), led to the discovery of the tumor. 6435852 Human
pancreatic polypeptide intestinal carcinoid tumors The intestinal carcinoid tumors of 26 patients were stained for the presence of serotonin, gastrin, somatostatin, motilin, secretin, glucagon, pancreatic polypeptide, ACTH, and neurotensin. 6187428 Human
pancreatic polypeptide liver metastases Treatment with interferon ameliorated the manifestations of the carcinoid syndrome and led to prompt and continuing decreases in urinary levels of 5-hydroxyindoleacetic acid and serum levels of human chorionic gonadotropin subunits and pancreatic polypept 6191217 Human
pancreatic polypeptide carcinoid syndrome Treatment with interferon ameliorated the manifestations of the carcinoid syndrome and led to prompt and continuing decreases in urinary levels of 5-hydroxyindoleacetic acid and serum levels of human chorionic gonadotropin subunits and pancreatic polypept 6191217 Human
pancreatic polypeptide gastric cancer The plasma pancreatic polypeptide response to a meal was compared in 6 healthy controls and 30 patients with gastric cancer who had undergone either subtotal gastrectomy or total gastrectomy with radical lymph node dissection including sympathectomy. 6622751 Human
pancreatic polypeptide metastases Thirty-one primary canine pancreatic endocrine tumors and their metastases were studied histologically and immunohistochemically for the presence of insulin, glucagon, somatostatin, pancreatic polypeptide (PP), gastrin, and adrenocorticotrophic hormone (A 2887054 Human
pancreatic polypeptide small cell carcinoma of the lung Plasma samples from 21 patients with small cell carcinoma of the lung were screened for pancreatic polypeptide, somatostatin, motilin, and vasoactive intestinal polypeptide. 2892280 Human
pancreatic polypeptide gangliocytic paraganglioma In contrast, the endocrine cells of the gangliocytic paraganglioma were positive for pancreatic polypeptide and serotonin, were negative for somatostatin, and contained conspicuous intracytoplasmic aggregates of filaments. 2894342 Human
pancreatic polypeptide intestinal-type adenocarcinomas Serotonin-immunoreactive cells were demonstrated in three of the seven intestinal-type adenocarcinomas, two of which also had cells that stained for somatostatin pancreatic polypeptide and cholecystokinin. 3953931 Human
pancreatic polypeptide adenomas In these adenomas subsequently immunocytochemistry revealed the presence of the neuro-hormonal peptides glucagon, pancreatic polypeptide and somatostatin as well as serotonin, in a pattern similar to that seen in normal colorectal mucosa. 2871146 Human
pancreatic polypeptide medullary carcinoma Pancreatic polypeptide immunoreactivity in medullary carcinoma of the thyroid: identification and characterisation by radioimmunoassay, immunocytochemistry and high performance liquid chromatography. 2872701 Human
pancreatic polypeptide insulinomas Endocrine pancreatic tumors producing vasoactive intestinal polypeptide, gastrin, somatostatin, and/or pancreatic polypeptide as well as the epithelium of pancreatic ducts were also stained with the antibodies, whereas a large number of other normal and a 2368442 Human
pancreatic polypeptide neoplasms The measurement of plasma levels of human pancreatic polypeptide (hPP) has been reported to be clinically useful in predicting the existence of pancreatic islet cell neoplasms in patients with familial multiple endocrine neoplasia type 1 (FMEN-I) and the 2174193 Human
pancreatic polypeptide metastatic disease The measurement of plasma levels of human pancreatic polypeptide (hPP) has been reported to be clinically useful in predicting the existence of pancreatic islet cell neoplasms in patients with familial multiple endocrine neoplasia type 1 (FMEN-I) and the 2174193 Human
pancreatic polypeptide islet-cell tumors The measurement of plasma levels of human pancreatic polypeptide (hPP) has been reported to be clinically useful in predicting the existence of pancreatic islet cell neoplasms in patients with familial multiple endocrine neoplasia type 1 (FMEN-I) and the 2174193 Human
pancreatic polypeptide multiple endocrine neoplasia type 1 The measurement of plasma levels of human pancreatic polypeptide (hPP) has been reported to be clinically useful in predicting the existence of pancreatic islet cell neoplasms in patients with familial multiple endocrine neoplasia type 1 (FMEN-I) and the 2174193 Human
pancreatic polypeptide medullary carcinomas Immunocytochemical localization and identification of members of the pancreatic polypeptide (PP)-fold family in human thyroid C cells and medullary carcinomas. 2274682 Human
pancreatic polypeptide tumour Other clinically useful tumour markers are chromogranin A + B, pancreatic polypeptide, human chorionic gonadotropin alpha and beta subunits. 2662260 Human
pancreatic polypeptide glucagonoma syndrome A malignant tumor of the pancreas producing the glucagonoma syndrome and associated with high plasma levels of glucagon and pancreatic polypeptide was studied histologically, ultrastructurally, and immunocytochemically. 2548179 Human
pancreatic polypeptide teratomas The pancreatic tissue in all six teratomas contained abundant mature islets that contained beta, alpha, delta, and pancreatic polypeptide cells; however, they also showed widespread nesidioblastosis with the same cell types, resembling third-trimester fet 8311655 Human
pancreatic polypeptide pancreatic adenocarcinomas Nine human exocrine pancreatic adenocarcinomas were examined by serial sectioning and double- and triple-labeled immunohistochemical techniques with antibodies against chromogranin A, insulin, islet amyloid polypeptide, glucagon, somatostatin, pancreatic 8379530 Human
pancreatic-polypeptide ductal adenocarcinoma Pancreatic-polypeptide in the human pancreas: expression and quantitative variation during development and in ductal adenocarcinoma. 12747533 Human
pancreatic-polypeptide pancreatic cancer AIM: To determine the immunoreactivity of pancreatic-polypeptide (PP) during the development of the human fetal pancreas and ductal pancreatic adenocarcinoma, given that, PP positive cells were demonstrated either into its embryonic anlage or into pancrea 12747533 Human
pancreatic polypeptide human pancreatic cancer Thirty-eight human pancreatic cancer specimens were studied for the reactivity of cancer cells with monoclonal antibodies against insulin, glucagon, somatostatin, pancreatic polypeptide (PP), vasoactive intestinal peptide (VIP), gastrin, calcitonin, and w 1316418 Human
pancreatic polypeptide malignant islet cell tumor From the results of histological and immunohistochemical studies, this was diagnosed as a malignant islet cell tumor producing multiple hormones such as insulin, glucagon, somatostatin and pancreatic polypeptide, as well as expressing the tumor-related an 1675032 Human
pancreatic polypeptide barrett's esophagus Immunohistochemistry was performed on biopsies of columnar mucosa from 11 patients with Barrett's esophagus and 11 patients with columnar mucosa in the cranial esophagus, the "inlet patch." Both epithelia contained endocrine cells, immunore 2295298 Human
pancreatic polypeptide neoplasm The neoplasm stained positive for glucagon and pancreatic polypeptide, but there were no clinical abnormalities that suggested hyperfunction. 2156258 Human
pancreatic polypeptide adenocarcinoma of the stomach The first case exhibited adenocarcinoma of the stomach with metastases to the neck lymph nodes and pancreatic polypeptide hypersecretion. 6991821 Human
pancreatic polypeptide tumor These results indicate that (1) VIP is a good tumor marker for the WDHA syndrome due to VIP-producing tumors; (2) patients with the WDHA syndrome are sometimes associated with MEN1; and (3) VIP-producing tumors are multiple hormone-producing tumors, and V 7014208 Human
pancreatic polypeptide tumors These results indicate that (1) VIP is a good tumor marker for the WDHA syndrome due to VIP-producing tumors; (2) patients with the WDHA syndrome are sometimes associated with MEN1; and (3) VIP-producing tumors are multiple hormone-producing tumors, and V 7014208 Human
pancreatic polypeptide gastrinoma Serum levels of pancreatic polypeptide (PP) were determined in 32 normal subjects, 18 patients with gastrinoma, 19 patients with pituitary adenoma and 11 patients with duodenal ulceration. 292374 Human
pancreatic polypeptide malignant tumors [Pancreatic endocrine F-cell tumor] Two cases of pancreatic F-cell malignant tumors, producing only pancreatic polypeptide (PP) with clinical, biochemical and immunohistochemical features are described. 7986606 Human
pancreatic polypeptide medullary carcinoma of the thyroid Pancreatic polypeptide immunoreactivity in medullary carcinoma of the thyroid: identification and characterisation by radioimmunoassay, immunocytochemistry and high performance liquid chromatography. 2872701 Human
pancreatic polypeptide tumors [Abnormal increase in pancreatic polypeptide in the secretin-provocation test: hypoglycemia-induced?] Pancreatic polypeptide (PP) can be used as a marker for endocrine active tumors originating from the pancreas. 7740287 Human
pancreatic polypeptide tumors of the pancreas Serum levels of pancreatic polypeptide may be found elevated as a diagnostic index in patients with endocrine peptide tumors of the pancreas. 856699 Human
pancreatic polypeptide endocrine tumors BACKGROUND: Augmented secretion of pancreatic polypeptide (PP) has been demonstrated in patients with severe systemic diseases or endocrine tumors. 15330207 Human
pancreatic polypeptide strumal carcinoid The trabecular parts of the 4 cases of strumal carcinoid were positive for pancreatic polypeptide. 8037803 Human
pancreatic polypeptide gastric neuroendocrine tumors Gastric neuroendocrine tumors, on the other hand, tend to display immunoreactivity to serotonin but may include small subpopulations producing gastrin, motilin, pancreatic polypeptide, and somatostatin. 1359688 Human
pancreatic polypeptide islet cell neoplasms The measurement of plasma levels of human pancreatic polypeptide (hPP) has been reported to be clinically useful in predicting the existence of pancreatic islet cell neoplasms in patients with familial multiple endocrine neoplasia type 1 (FMEN-I) and the 2174193 Human
pnp bph The offspring of pregnant rats administered TCDD had markedly elevated hepatic PNP UDP-glucuronyltransferase (UDPGT) BPH, and microsomal cytochrome contents whereas the perinatal development of testosterone UDPGT was unchanged. 806369 Human
pancreatic polypeptide tumourbearing Twenty days after subcutaneous transplantation, tumour-bearing rats exhibited marked hyperinsulinaemia and hypoglycaemia, with plasma pancreatic polypeptide concentrations similar to controls. 2987070 Human
pancreatic polypeptide rectal tumors Peptide YY cell population in the rectal tumors was small to moderate in comparison with pancreatic polypeptide and glucagon cell population. 2888260 Human
pancreatic polypeptide paragangliomas Ganglioneuromatous paragangliomas combined somatostatin and/or pancreatic polypeptide containing endocrine cells with protein-S100-positive Schwann cells. 2160422 Human
pancreatic polypeptide phaeochromocytoma METHODS: Levels of chromogranin A, neurone specific enolase, protein gene peptide 9.5, pancreatic polypeptide, and the chromogranin-derived peptides, intervening peptide and vasostatin-1 were examined by immunocytochemistry in rat phaeochromocytoma (PC12) 15582597 Rat
pancreatic polypeptide small cell carcinomas Sections of 29 small cell carcinomas from oesophagus, stomach, larynx, colon and urinary bladder were immunostained using antisera to protein gene product 9.5 (PGP 9.5), neuron-specific enolase (NSE), cytokeratin, leucocyte common antigen and peptides inc 3027289 Human
pancreatic polypeptide colorectal adenocarcinomas An immunocytochemical study. Colorectal adenocarcinomas were induced in male Wistar rats, by weekly subcutaneous administration of 1,2-dimethylhydrazine, classified according to the degree of differentiation and submitted to immunocytochemistry for the pe 3779800 Rat
pancreatic polypeptide pancreatic endocrine tumour A rise in basal plasma pancreatic polypeptide has been observed in about 50% of cases of familial MEN I (Wermer's syndrome) and appears to be a good index of pancreatic endocrine tumour.When ZES is associated with HPT I, the latter should be treated 6123105 Human
pancreatic polypeptide islet cell tumors The measurement of plasma levels of human pancreatic polypeptide (hPP) has been reported to be clinically useful in predicting the existence of pancreatic islet cell neoplasms in patients with familial multiple endocrine neoplasia type 1 (FMEN-I) and the 2174193 Human
pancreatic polypeptide carcinoma The distribution and density of gastric endocrine cells in Balb/c mice bearing CT-26 carcinoma cells were studied immunohistochemically employing specific antisera against serotonin, somatostatin, glucagon, gastrin, cholecystokinin (CCK)-8 and human pancr 17213038 Mouse
pancreatic polypeptide head cancer [The modes of spread of pancreas head cancer based on difference of the pancreatic anlagen] Embryologically the pancreas head consists of a dorsal and a ventral portion and these were able to be differentiated by the shape of the islets and the density of 2671642 Human
pancreatic polypeptide adenocarcinoma of the bile duct Circulating pancreatic polypeptide in patients with adenocarcinoma of the bile duct. 8260180 Human
pancreatic polypeptide endocrine pancreatic tumors Endocrine pancreatic tumors producing vasoactive intestinal polypeptide, gastrin, somatostatin, and/or pancreatic polypeptide as well as the epithelium of pancreatic ducts were also stained with the antibodies, whereas a large number of other normal and a 2368442 Human
pancreatic polypeptide bronchial carcinoid tumors Serum pancreatic polypeptide (PP) and human chorionic gonadotrophin alpha levels were elevated in 43% and 28% of the patients, respectively, and the highest levels were found in patients with metastatic bronchial carcinoid tumors. 2440390 Human
pancreatic polypeptide medullary carcinoma of thyroid Pancreatic polypeptide immunoreactivity has been identified in primary medullary carcinoma of thyroid using radioimmunoassay and immunocytochemistry and subsequently characterised by HPLC. 2872701 Human
pancreatic polypeptide hyperplastic Immunohistochemically, the tumor cells of both cases were positive for the epithelial markers (AE1/AE3 and CAM 5.2), and in one of the two cases, the tumor cells and hyperplastic cells surrounding the tumor conspicuously revealed multiple hormonal markers 8392902 Human
pancreatic polypeptide rectal neuroendocrine tumors [Immunohistochemical study of 17 cases of rectal neuroendocrine tumors] Seventeen rectal neuroendocrine tumors ("Rectal Carcinoids") were studied by immunohistochemistry using antibodies directed against neuroendocrine markers: chromogranin A, n 8767675 Human
pancreatic polypeptide tumor [Pancreatic endocrine F-cell tumor] Two cases of pancreatic F-cell malignant tumors, producing only pancreatic polypeptide (PP) with clinical, biochemical and immunohistochemical features are described. 7986606 Human
pancreatic polypeptide multiple endocrine neoplasia type i Genetic, clinical, and biochemical analysis of unrelated Spanish families with multiple endocrine neoplasia type I. OBJECTIVE: (1) To study seven unrelated Spanish families with multiple endocrine neoplasia type I (MEN I), describing clinical features and 11419921 Human
pancreatic polypeptide intestinal tumors In contrast, the largest immunoreactive subpopulation of intestinal tumors expressed secretin (53% of total cells), followed by proglucagon-related peptides (15%), glucose-dependent insulinotropic polypeptide (7%), gastrin (7%), pancreatic polypeptide (2% 2162628 Human
pancreatic polypeptide metastases to the neck The first case exhibited adenocarcinoma of the stomach with metastases to the neck lymph nodes and pancreatic polypeptide hypersecretion. 6991821 Human
pancreatic polypeptide mucinous tumors In the cervix, they were confined to remarkable mucinous tumors related to "adenoma malignum." Serotonin, somatostatin, gastrin, and pancreatic polypeptide immunoreactive cells were characterized. 3902686 Human
pancreatic polypeptide neuroendocrine tumours The secretion of pancreatic polypeptide has been used as a marker for neuroendocrine tumours but is considered to be a biologically inert peptide. 10071589 Human
pancreatic polypeptide nonfunctioning pancreatic endocrine tumors METHODS: Using labeled streptavidin-biotin (LSAB), immunohistochemical staining for insulin, glucagon, somatostatin, pancreatic polypeptide and gastrin was performed on 30 nonfunctioning pancreatic endocrine tumors from 30 patients. 10374408 Human
pancreatic polypeptide gastroenteropancreatic tumors Genetic, clinical, and biochemical analysis of unrelated Spanish families with multiple endocrine neoplasia type I. OBJECTIVE: (1) To study seven unrelated Spanish families with multiple endocrine neoplasia type I (MEN I), describing clinical features and 11419921 Human
pancreatic polypeptide lung carcinoma AIM: To study the distributions and frequencies of intestinal endocrine cells in the C57BL/6 mouse with immunohistochemical method using seven types of specific antisera against chromogranin A (CGA), serotonin, somatostatin, glucagons, gastrin, cholecysto 16222737 Mouse
pancreatic polypeptide carcinoid Peptide hormone immunostaining disclosed the presence of glucagon and pancreatic polypeptide (PP) in the bronchial carcinoid, whereas the ovarian carcinoid showed no immunoreactivity with the antisera used. 3536680 Human
pancreatic polypeptide malignant endocrine tumours Meal-stimulated and atropine-inhibited secretion of pancreatic polypeptide in healthy subjects, members of MEA I families and patients with malignant endocrine tumours of the gastrointestinal tract. 6133318 Human
pancreatic polypeptide an adenocarcinoma Gastrointestinal hormone levels were elevated (vasoactive intestinal polypeptide 950 pg/ml, pancreatic polypeptide 1000 pmol/l and neurotensin 86 pmol/l) in the blood, and immunohistochemical results on cells of an adenocarcinoma obtained by needle biopsy 2551624 Human
pancreatic polypeptide apudoma Both tumors contained hPP predominantly by immunocytochemistry; one, a pure pancreatic polypeptide apudoma, was studied extensively demonstrating also by radioimmunoassay a high content of hPP and negligible amounts of insulin, glucagon, somatostatin, vas 6243207 Human
pancreatic polypeptide bile duct tumors Serum pancreatic polypeptide assays warrant evaluation as an aid in the diagnosis and management of patients with bile duct tumors. 8260180 Human
pancreatic polypeptide lung carcinoma AIM: The regional distributions and relative frequencies of some gastric endocrine cells of C57BL/6 mice were studied by immunohistochemical method using seven types of specific antisera against chromogranin A (CGA), serotonin, somatostatin, gastrin, chol 15761969 Human
pancreatic polypeptide neuroendocrine carcinoma The authors report a case of a suspected pure pancreatic polypeptide-secreting neuroendocrine carcinoma of the gallbladder. 9892273 Human
pancreatic polypeptide mixed tumors Pancreatic polypeptide-related tumors. PP-producing tumors are mostly located in the pancreas and may present as three pathologic lesions: pure PP-omas, mixed tumors with minor PP cell population, and PP-cell hyperplasia. 11825648 Human
pancreatic polypeptide tumor antigens These tools include tumor antigens or products (e.g., carbohydrate antigen [CA] 19-9), cytokines (e.g., interleukin-6), metabolic products (e.g., lactate), proteases (e.g., trypsinogen-2), regulatory peptides (e.g., pancreatic polypeptide), and (epi-)gene 15192787 Human
pancreatic polypeptide pancreatic neuroendocrine tumors BACKGROUND: Sporadic pancreatic neuroendocrine tumors, which predominantly secrete pancreatic polypeptide (PPoma), are rare and have not been associated with a clinical syndrome. 18521664 Human

< Top >


Download all image files.
Save all PNG files.    Save all PDF files.    Save all PS files.