IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene NSF Ensembl ENSG00000073969 Chromosome 17 Start 42023391 End 42190000
Description Vesicle-fusing ATPase (EC 3.6.4.6)(N-ethylmaleimide-sensitive fusion protein)(NEM-sensitive fusion protein)(Vesicular-fusion protein NSF) [Source:UniProtKB/Swiss-Prot;Acc:P46459]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 8016
     Entrez Gene : 4905
     UCSC : uc002iku.2
     GeneCards : 8016
     RefSeq : NM_006178
     CCDS : CCDS42354.1
     Uniprot : P46459
     Interpro : P46459
     OMIM : 601633
     GeneTests : NSF
     CGAP : NSF
     PMID : 1315316

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  38719_at  0.55  1.32e-9  1.60e-8  0.49  5.21e-6  2.81e-5
 HG_U133A  202395_at  0.68  1.39e-26  1.72e-25  0.04  4.11e-1  4.21e-1
 HG_U133_Plus2  202395_at  0.53  3.89e-11  3.26e-10  -0.09  3.54e-1  4.15e-1
 Stanford  5457  0.50  2.15e-1  4.08e-1  0.60  6.24e-2  1.98e-1
 Stanford  13883  0.65  1.54e-2  8.48e-2  0.32  3.19e-1  5.59e-1
 Agilent_HS_21.6K  12687  0.02  5.23e-1  6.93e-1  -0.01  7.38e-1  8.32e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  202395_at  0.05  8.24e-1  9.84e-1  -0.07  5.77e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 38719_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 202395_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 202395_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 5457    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 13883    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 12687    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
nsf rat insulinoma NSF was found to be present in the cytosol of rat pancreatic beta-cells and rat insulinoma INS-1 cells. 12887318 Rat
nsf tumor To investigate the role of NSF in mast cell degranulation, we developed an assay to measure secretion from transiently transfected RBL (rat basophilic leukemia)-2H3 mast cells (a tumor analog of mucosal mast cells). 14607937 Rat
nsf human neuroblastoma Western blot analysis showed that the human neuroblastoma SH-SY5Y expresses the proteins synaptotagmin l, synaptobrevin, synapsin-l, rab3a, syntaxin, SNAP-25, NSF, alpha-SNAP, and munc-18, which have been implicated in the movement, docking, and fusion of 9084425 Human

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