IGDB.NSCLC Gene View
Gene Information Microarray Gene Expression Result Treatment Result Microarray Sample Data Cancer Gene Index
 
Gene Information        (help)
Gene CDC27 Ensembl ENSG00000004897 Chromosome 17 Start 42552625 End 42621664
Description Cell division cycle protein 27 homolog (CDC27Hs)(H-NUC) [Source:UniProtKB/Swiss-Prot;Acc:P30260]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 1728
     Entrez Gene : 996
     UCSC : uc002ile.3
     GeneCards : 1728
     RefSeq : NM_001114091
     CCDS : CCDS11509.1
     Uniprot : P30260
     Interpro : P30260
     OMIM : 116946
     GeneTests : CDC27
     CGAP : CDC27
     PMID : 8234252

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  40591_at  0.19  2.44e-1  3.44e-1  0.43  9.43e-2  1.56e-1
 HG_U133A  214236_at  -0.21  4.36e-2  6.13e-2  1.93  1.49e-29  2.49e-29
 HG_U133A  217878_s_at  0.53  5.27e-9  1.71e-8  -2.91  4.38e-71  1.45e-70
 HG_U133A  217879_at  0.08  8.25e-2  1.10e-1  -4.03  1.26e-41  2.51e-41
 HG_U133A  217880_at  -0.04  6.39e-1  6.83e-1  -2.57  1.74e-75  6.34e-75
 HG_U133A  217881_s_at  0.26  3.86e-3  6.45e-3  -0.31  1.85e-4  2.10e-4
 HG_U133_Plus2  214236_at  0.61  8.36e-4  2.21e-3  1.38  5.90e-12  3.27e-11
 HG_U133_Plus2  217878_s_at  0.85  1.17e-6  5.21e-6  1.20  4.77e-18  5.31e-17
 HG_U133_Plus2  217879_at  0.38  1.92e-9  1.29e-8  0.58  1.19e-16  1.13e-15
 HG_U133_Plus2  217880_at  0.08  2.93e-1  3.80e-1  0.14  7.60e-2  1.05e-1
 HG_U133_Plus2  217881_s_at  0.04  7.00e-1  7.66e-1  0.00  9.99e-1  9.99e-1
 Stanford  9294  -1.27  2.30e-3  2.48e-2  -1.20  1.56e-2  9.41e-2
 Stanford  13654  0.33  3.37e-1  5.38e-1  0.53  6.05e-2  1.94e-1
 Stanford  22269  0.19  2.98e-1  5.01e-1  0.11  7.71e-1  8.91e-1
 Agilent_HS_21.6K  18450  -0.03  6.31e-1  7.75e-1  0.05  4.47e-1  6.03e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  214236_at  -0.64  1.01e-1  7.75e-1  -0.13  5.72e-1  1.00e+0
 HG_U133A  217878_s_at  -0.21  4.95e-1  9.27e-1  -0.10  4.19e-1  1.00e+0
 HG_U133A  217879_at  0.01  9.79e-1  9.99e-1  -0.02  8.71e-1  1.00e+0
 HG_U133A  217880_at  -0.25  4.57e-1  9.16e-1  0.08  6.84e-1  1.00e+0
 HG_U133A  217881_s_at  -0.61  1.38e-1  8.02e-1  -0.28  4.90e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 40591_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 214236_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 217878_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 217879_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 217880_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 217881_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 214236_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 217878_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 217879_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 217880_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 217881_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 9294    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 13654    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 22269    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 18450    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
cdc27 tumor Cloning genes encoding MHC class II-restricted antigens: mutated CDC27 as a tumor antigen. 10334988 Human
cdc27 tumor antigen Cloning genes encoding MHC class II-restricted antigens: mutated CDC27 as a tumor antigen. 10334988 Human

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