IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene CDC27 Ensembl ENSG00000004897 Chromosome 17 Start 42552625 End 42621664
Description Cell division cycle protein 27 homolog (CDC27Hs)(H-NUC) [Source:UniProtKB/Swiss-Prot;Acc:P30260]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 1728
     Entrez Gene : 996
     UCSC : uc002ile.3
     GeneCards : 1728
     RefSeq : NM_001114091
     CCDS : CCDS11509.1
     Uniprot : P30260
     Interpro : P30260
     OMIM : 116946
     GeneTests : CDC27
     CGAP : CDC27
     PMID : 8234252

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  40591_at  0.19  2.44e-1  3.44e-1  0.43  9.43e-2  1.56e-1
 HG_U133A  214236_at  -0.21  4.36e-2  6.13e-2  1.93  1.49e-29  2.49e-29
 HG_U133A  217878_s_at  0.53  5.27e-9  1.71e-8  -2.91  4.38e-71  1.45e-70
 HG_U133A  217879_at  0.08  8.25e-2  1.10e-1  -4.03  1.26e-41  2.51e-41
 HG_U133A  217880_at  -0.04  6.39e-1  6.83e-1  -2.57  1.74e-75  6.34e-75
 HG_U133A  217881_s_at  0.26  3.86e-3  6.45e-3  -0.31  1.85e-4  2.10e-4
 HG_U133_Plus2  214236_at  0.61  8.36e-4  2.21e-3  1.38  5.90e-12  3.27e-11
 HG_U133_Plus2  217878_s_at  0.85  1.17e-6  5.21e-6  1.20  4.77e-18  5.31e-17
 HG_U133_Plus2  217879_at  0.38  1.92e-9  1.29e-8  0.58  1.19e-16  1.13e-15
 HG_U133_Plus2  217880_at  0.08  2.93e-1  3.80e-1  0.14  7.60e-2  1.05e-1
 HG_U133_Plus2  217881_s_at  0.04  7.00e-1  7.66e-1  0.00  9.99e-1  9.99e-1
 Stanford  9294  -1.27  2.30e-3  2.48e-2  -1.20  1.56e-2  9.41e-2
 Stanford  13654  0.33  3.37e-1  5.38e-1  0.53  6.05e-2  1.94e-1
 Stanford  22269  0.19  2.98e-1  5.01e-1  0.11  7.71e-1  8.91e-1
 Agilent_HS_21.6K  18450  -0.03  6.31e-1  7.75e-1  0.05  4.47e-1  6.03e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  214236_at  -0.64  1.01e-1  7.75e-1  -0.13  5.72e-1  1.00e+0
 HG_U133A  217878_s_at  -0.21  4.95e-1  9.27e-1  -0.10  4.19e-1  1.00e+0
 HG_U133A  217879_at  0.01  9.79e-1  9.99e-1  -0.02  8.71e-1  1.00e+0
 HG_U133A  217880_at  -0.25  4.57e-1  9.16e-1  0.08  6.84e-1  1.00e+0
 HG_U133A  217881_s_at  -0.61  1.38e-1  8.02e-1  -0.28  4.90e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 40591_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 214236_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 217878_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 217879_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 217880_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 217881_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 214236_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 217878_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 217879_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 217880_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 217881_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 9294    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 13654    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 22269    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 18450    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
cdc27 tumor Cloning genes encoding MHC class II-restricted antigens: mutated CDC27 as a tumor antigen. 10334988 Human
cdc27 tumor antigen Cloning genes encoding MHC class II-restricted antigens: mutated CDC27 as a tumor antigen. 10334988 Human

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