IGDB.NSCLC Gene View
Gene Information
Microarray Gene Expression Result
Treatment Result
Microarray Sample Data
Cancer Gene Index
Gene Information
(help)
Gene
NFE2L1
Ensembl
ENSG00000082641
Chromosome
17
Start
43480720
End
43493836
Description
Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1)(NFE2-related factor 1)(Nuclear factor, erythroid derived 2, like 1)(Transcription factor 11)(Transcription factor HBZ17)(Transcription factor LCR-F1)(Locus control region-factor 1) [Source:UniProtKB/Swiss-Prot;Acc:Q14494]
GENE RESOURCES :
NUCLEOTIDE SEQUENCES :
PROTEIN RESOURCES :
CLINICAL RESOURCES :
REFERENCES :
HGNC : 7781
Entrez Gene : 4779
UCSC : uc002imz.3
GeneCards : 7781
RefSeq : NM_003204
CCDS : CCDS11524.1
Uniprot : Q14494
Interpro : Q14494
OMIM : 163260
GeneTests : NFE2L1
CGAP : NFE2L1
PMID : 8248256
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Microarray Gene Expression Fold Change Result
(help)
(
red: up-regulation
/
green : down-regulation
when p value < 0.01)
( gray background : these probesets might have mapping problems.
ref 1
,
ref 2
)
Chip Type
Probeset
Adenocarcinoma
Squamous Cell Carcinoma
Fold Change
p value
q value
Fold Change
p value
q value
HG_U95
38439_at
-0.32
2.87e-5
1.34e-4
0.30
5.94e-3
1.47e-2
HG_U133A
200758_s_at
0.04
4.41e-1
4.97e-1
-1.33
4.85e-53
1.16e-52
HG_U133A
200759_x_at
-0.23
3.88e-6
9.42e-6
-1.12
1.15e-62
3.26e-62
HG_U133A
214179_s_at
-0.09
9.91e-2
1.30e-1
-4.62
2.11e-81
8.84e-81
HG_U133_Plus2
200758_s_at
0.04
5.66e-1
6.48e-1
0.83
3.40e-18
3.85e-17
HG_U133_Plus2
200759_x_at
-0.10
1.16e-1
1.73e-1
0.41
3.10e-7
9.73e-7
HG_U133_Plus2
214179_s_at
-0.08
2.53e-1
3.36e-1
0.57
1.89e-10
8.76e-10
Stanford
1519
0.38
1.04e-1
2.55e-1
0.89
4.12e-2
1.49e-1
Agilent_HS_21.6K
907
-0.03
1.16e-1
2.60e-1
-0.01
5.57e-1
6.96e-1
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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result
(help)
(Pubmed)
(
red: up-regulation
/
green : down-regulation
when p value < 0.01)
( gray background color : the mapping problems of probeset.
ref_1
,
ref_2
)
Chip Type
Probeset
Adenocarcinoma
Squamous Cell Carcinoma
Fold Change
p value
q value
Fold Change
p value
q value
HG_U133A
200758_s_at
0.02
9.35e-1
9.96e-1
0.17
2.66e-1
1.00e+0
HG_U133A
200759_x_at
-0.03
8.97e-1
9.94e-1
0.26
7.62e-2
1.00e+0
HG_U133A
214179_s_at
-0.11
5.55e-1
9.41e-1
0.16
2.53e-1
1.00e+0
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Microarray Sample Data
(help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
HG_U95
- 38439_at
(back)
HG_U133A
- 200758_s_at
(back)
HG_U133A
- 200759_x_at
(back)
HG_U133A
- 214179_s_at
(back)
HG_U133_Plus2
- 200758_s_at
(back)
HG_U133_Plus2
- 200759_x_at
(back)
HG_U133_Plus2
- 214179_s_at
(back)
Stanford
- 1519
(back)
Agilent_HS_21.6K
- 907
(back)
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Cancer Gene Index
(help)
If 0 entry was found, please remove the search key "lung cancer".
Keyword
DiseaseData
Statement
PubMed
Organism
nrf1
cancer
Effect of four genes (ALDH1, NRF1, JAM and KBL) on proliferation arrest in a non-small cell bronchopulmonary cancer line.
12174908
Human
nrf1
neoplasia
Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia.
15738389
Mouse
nrf1
hepatic cancer
We report here that mice with somatic inactivation of nrf1 in the liver developed hepatic cancer.
15738389
Mouse
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