IGDB.NSCLC Gene View
Gene Information Microarray Gene Expression Result Treatment Result Microarray Sample Data Cancer Gene Index
 
Gene Information        (help)
Gene NFE2L1 Ensembl ENSG00000082641 Chromosome 17 Start 43480720 End 43493836
Description Nuclear factor erythroid 2-related factor 1 (NF-E2-related factor 1)(NFE2-related factor 1)(Nuclear factor, erythroid derived 2, like 1)(Transcription factor 11)(Transcription factor HBZ17)(Transcription factor LCR-F1)(Locus control region-factor 1) [Source:UniProtKB/Swiss-Prot;Acc:Q14494]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 7781
     Entrez Gene : 4779
     UCSC : uc002imz.3
     GeneCards : 7781
     RefSeq : NM_003204
     CCDS : CCDS11524.1
     Uniprot : Q14494
     Interpro : Q14494
     OMIM : 163260
     GeneTests : NFE2L1
     CGAP : NFE2L1
     PMID : 8248256

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  38439_at  -0.32  2.87e-5  1.34e-4  0.30  5.94e-3  1.47e-2
 HG_U133A  200758_s_at  0.04  4.41e-1  4.97e-1  -1.33  4.85e-53  1.16e-52
 HG_U133A  200759_x_at  -0.23  3.88e-6  9.42e-6  -1.12  1.15e-62  3.26e-62
 HG_U133A  214179_s_at  -0.09  9.91e-2  1.30e-1  -4.62  2.11e-81  8.84e-81
 HG_U133_Plus2  200758_s_at  0.04  5.66e-1  6.48e-1  0.83  3.40e-18  3.85e-17
 HG_U133_Plus2  200759_x_at  -0.10  1.16e-1  1.73e-1  0.41  3.10e-7  9.73e-7
 HG_U133_Plus2  214179_s_at  -0.08  2.53e-1  3.36e-1  0.57  1.89e-10  8.76e-10
 Stanford  1519  0.38  1.04e-1  2.55e-1  0.89  4.12e-2  1.49e-1
 Agilent_HS_21.6K  907  -0.03  1.16e-1  2.60e-1  -0.01  5.57e-1  6.96e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  200758_s_at  0.02  9.35e-1  9.96e-1  0.17  2.66e-1  1.00e+0
 HG_U133A  200759_x_at  -0.03  8.97e-1  9.94e-1  0.26  7.62e-2  1.00e+0
 HG_U133A  214179_s_at  -0.11  5.55e-1  9.41e-1  0.16  2.53e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 38439_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 200758_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 200759_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 214179_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 200758_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 200759_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 214179_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 1519    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 907    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
nrf1 cancer Effect of four genes (ALDH1, NRF1, JAM and KBL) on proliferation arrest in a non-small cell bronchopulmonary cancer line. 12174908 Human
nrf1 neoplasia Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia. 15738389 Mouse
nrf1 hepatic cancer We report here that mice with somatic inactivation of nrf1 in the liver developed hepatic cancer. 15738389 Mouse

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