IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene GRIK5 Ensembl ENSG00000105737 Chromosome 19 Start 47194317 End 47261797
Description Glutamate receptor, ionotropic kainate 5 Precursor (Glutamate receptor KA-2)(KA2)(Excitatory amino acid receptor 2)(EAA2) [Source:UniProtKB/Swiss-Prot;Acc:Q16478]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 4583
     Entrez Gene : 2901
     UCSC : uc002osj.1
     GeneCards : 4583
     RefSeq : NM_002088
     CCDS : CCDS12595.1
     Uniprot : Q16478
     Interpro : Q16478
     OMIM : 600283
     GeneTests : GRIK5
     CGAP : GRIK5
     PMID : 7527545

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  34904_at  0.53  4.17e-3  1.10e-2  0.93  8.26e-5  3.36e-4
 HG_U95  34905_at  0.60  1.49e-3  4.47e-3  0.59  1.42e-2  3.13e-2
 HG_U95  34906_g_at  0.33  3.23e-4  1.16e-3  0.50  1.99e-4  7.39e-4
 HG_U133A  214966_at  0.39  1.14e-2  1.77e-2  1.18  4.88e-11  6.21e-11
 HG_U133A  217509_x_at  -0.35  2.69e-6  6.62e-6  -2.52  1.31e-72  4.47e-72
 HG_U133_Plus2  1553168_at  0.59  2.17e-3  5.23e-3  1.08  1.22e-6  3.52e-6
 HG_U133_Plus2  214966_at  -0.43  3.00e-2  5.39e-2  -0.39  6.87e-2  9.57e-2
 HG_U133_Plus2  217509_x_at  0.31  1.14e-2  2.29e-2  0.35  2.33e-2  3.55e-2
 Agilent_HS_21.6K  920  -0.00  9.97e-1  9.98e-1  0.01  6.65e-1  7.79e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  214966_at  -0.37  4.56e-1  9.16e-1  0.06  8.49e-1  1.00e+0
 HG_U133A  217509_x_at  -0.15  5.20e-1  9.34e-1  -0.03  8.69e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 34904_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 34905_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 34906_g_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 214966_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 217509_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1553168_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 214966_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 217509_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 920    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
grik2 human teratocarcinoma The availability of the data on the genomic organization allowed the study of GRIK2 gene expression by RT-PCR analysis which was performed on human teratocarcinoma cell cultures (NT2) and on mRNA obtained from human hippocampus (Clontech). 11675011 Human
ka-2 rat insulinoma Rat insulinoma cells expressed GluR5 and KA-2 non-NMDA and NR1 and NR2D NMDA GluR mRNAs. 8915893 Rat

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