IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene ETHE1 Ensembl ENSG00000105755 Chromosome 19 Start 48702712 End 48723236
Description Protein ETHE1, mitochondrial Precursor (EC 3.-.-.-)(Ethylmalonic encephalopathy protein 1)(Hepatoma subtracted clone one protein) [Source:UniProtKB/Swiss-Prot;Acc:O95571]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :
     HGNC : 23287
     Entrez Gene : 23474
     UCSC : uc002owp.2
     GeneCards : 23287
     RefSeq : NM_014297
     CCDS : CCDS12622.1
     Uniprot : O95571
     Interpro : O95571
     OMIM : 608451
     GeneTests : ETHE1
     CGAP : ETHE1

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  36170_at  -0.01  9.00e-1  9.29e-1  0.15  1.52e-1  2.33e-1
 HG_U133A  204034_at  -0.35  4.95e-6  1.19e-5  -1.16  6.15e-46  1.31e-45
 HG_U133_Plus2  204034_at  -0.02  8.38e-1  8.78e-1  0.19  5.04e-2  7.22e-2
 Agilent_HS_21.6K  1569  -0.09  1.69e-1  3.35e-1  -0.09  2.21e-1  3.69e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  204034_at  0.21  3.00e-1  8.75e-1  -0.09  5.48e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 36170_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 204034_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 204034_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 1569    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
yf13h12 gastric cancer Commonly up-regulated genes in gastric cancer in comparison with normal gastric epithelia included CEACAM6, APOC1 and YF13H12. 15132764 Human
yf13h12 tumor Frequently overexpressed genes (tumor/normal ratio > 2) were COL1A1 (percentage of cases with overexpression, 78.3%), CDH17 (73.9%), APOC1 (67.4%), COL1A2 (58.7%), YF13H12 (52.2%), CEACAM6 (50.0%), APOE (50.0%), REGIV (47.8%), S100A11 (41.3%), and FUS (41 15059891 Human
hsco hepatocellular carcinomas HSCO mRNA was overexpressed in 20 of 30 hepatocellular carcinomas analyzed. 12398897 Human
hsco hepatocarcinogenesis These results suggest that overexpression of HSCO suppresses p53-induced apoptosis by preventing nuclear localization of NF-kappa B during signaling and thus contributes to hepatocarcinogenesis. 12398897 Human
ethe1 hepatocellular carcinomas HSCO (hepatoma subtracted-cDNA library clone one, also called ETHE1) was originally identified by its frequent overexpression in hepatocellular carcinomas. 17353187 Human
ethe1 hepatoma HSCO (hepatoma subtracted-cDNA library clone one, also called ETHE1) was originally identified by its frequent overexpression in hepatocellular carcinomas. 17353187 Human
hsco hepatocellular carcinomas HSCO (hepatoma subtracted-cDNA library clone one, also called ETHE1) was originally identified by its frequent overexpression in hepatocellular carcinomas. 17353187 Human
hsco hepatoma HSCO (hepatoma subtracted-cDNA library clone one, also called ETHE1) was originally identified by its frequent overexpression in hepatocellular carcinomas. 17353187 Human
hsco hepatocellular carcinomas Treatment of hepatocellular carcinomas that retain wild-type p53 and overexpress HSCO with anti-HSCO agents might re-establish the p53 response and revert chemoresistance. 17353187 Human

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