IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene BCAM Ensembl ENSG00000187244 Chromosome 19 Start 50004178 End 50016517
Description Lutheran blood group glycoprotein Precursor (B-CAM cell surface glycoprotein)(Auberger B antigen)(F8/G253 antigen)(CD239 antigen) [Source:UniProtKB/Swiss-Prot;Acc:P50895]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :
     HGNC : 6722
     Entrez Gene : 4059
     UCSC : uc002ozu.2
     GeneCards : 6722
     RefSeq : NM_001013257
     CCDS : CCDS12644.1
     Uniprot : P50895
     Interpro : P50895
     OMIM : 612773
     GeneTests : BCAM
     CGAP : BCAM

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  40093_at  -0.13  4.33e-1  5.40e-1  -0.90  2.11e-6  1.23e-5
 HG_U95  40094_r_at  0.70  6.44e-7  4.44e-6  0.85  2.60e-4  9.37e-4
 HG_U133A  203009_at  -0.52  1.32e-4  2.70e-4  1.90  2.97e-62  8.36e-62
 HG_U133A  40093_at  -0.90  3.04e-16  1.80e-15  -4.10  4.17e-92  2.28e-91
 HG_U133_Plus2  203009_at  0.37  3.90e-2  6.78e-2  0.74  1.62e-3  3.01e-3
 HG_U133_Plus2  40093_at  0.21  2.13e-1  2.91e-1  0.42  8.15e-2  1.12e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  203009_at  -0.90  9.73e-2  7.70e-1  0.10  7.36e-1  1.00e+0
 HG_U133A  40093_at  -0.34  3.16e-1  8.80e-1  0.24  3.35e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 40093_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 40094_r_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 203009_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 40093_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 203009_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 40093_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
b-cell adhesion molecule epithelial cancer The Lutheran (Lu) blood group antigens and the B-cell adhesion molecule (B-CAM) epithelial cancer antigen are carried by recently cloned integral glycoproteins that belong to the Ig superfamily. 9192786 Human
b-cell adhesion molecule epithelial cancer A unique gene encodes spliceoforms of the B-cell adhesion molecule cell surface glycoprotein of epithelial cancer and of the Lutheran blood group glycoprotein. 8781446 Human
b-cell adhesion molecule epithelial cancer Two new members of the Ig superfamily, the Lutheran (Lu) blood group glycoprotein and the B-cell adhesion molecule (B-CAM) epithelial cancer antigen, have been recently cloned from human placenta and colon cancer HT29 cell line, respectively. 8781446 Human
b-cell adhesion molecule colon cancer Two new members of the Ig superfamily, the Lutheran (Lu) blood group glycoprotein and the B-cell adhesion molecule (B-CAM) epithelial cancer antigen, have been recently cloned from human placenta and colon cancer HT29 cell line, respectively. 8781446 Human
lutheran blood group epithelial cancer A unique gene encodes spliceoforms of the B-cell adhesion molecule cell surface glycoprotein of epithelial cancer and of the Lutheran blood group glycoprotein. 8781446 Human
the lu mrna brain tumors Because many BBB specific genes are downregulated in tissue culture and in brain tumors, the expression of the LU mRNA and immunoactive LU protein was investigated in primary and metastatic human brain tumors. 10908043 Human
b-cell adhesion molecule primary tumor Importantly some components were differentially detected in the tetraspanin web of the three cell lines: the laminin receptor Lutheran/B-cell adhesion molecule (Lu/B-CAM) was expressed only on the primary tumor cells, whereas CD26/dipeptidyl peptidase IV 16467180 Human

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