IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene APOC1 Ensembl ENSG00000130208 Chromosome 19 Start 50109419 End 50114423
Description Apolipoprotein C-I Precursor (Apo-CI)(ApoC-I) [Source:UniProtKB/Swiss-Prot;Acc:P02654]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :
     HGNC : 607
     Entrez Gene : 341
     UCSC : uc002pae.1
     GeneCards : 607
     RefSeq : NM_001645
     CCDS : CCDS12648.1
     Uniprot : P02654
     Interpro : P02654
     OMIM : 107710
     GeneTests : APOC1
     CGAP : APOC1

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  41764_at  -0.65  8.53e-4  2.73e-3  -1.45  2.44e-8  2.09e-7
 HG_U133A  204416_x_at  -1.04  2.28e-15  1.26e-14  -3.44  1.35e-56  3.43e-56
 HG_U133A  213553_x_at  -0.80  6.35e-15  3.39e-14  1.40  5.26e-41  1.04e-40
 HG_U133_Plus2  204416_x_at  -1.20  4.98e-12  4.68e-11  -1.97  2.10e-14  1.54e-13
 HG_U133_Plus2  213553_x_at  -0.95  3.39e-11  2.86e-10  -1.45  1.00e-11  5.40e-11
 Stanford  21696  -0.96  7.42e-2  2.03e-1  -1.54  2.24e-2  1.16e-1
 Agilent_HS_21.6K  16533  -0.17  1.80e-1  3.48e-1  -0.41  9.46e-3  3.43e-2

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  204416_x_at  1.03  2.85e-2  6.98e-1  -0.19  6.61e-1  1.00e+0
 HG_U133A  213553_x_at  0.49  1.55e-1  8.12e-1  0.11  6.58e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 41764_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 204416_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 213553_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 204416_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 213553_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 21696    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 16533    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
apoc1 gastric cancer Commonly up-regulated genes in gastric cancer in comparison with normal gastric epithelia included CEACAM6, APOC1 and YF13H12. 15132764 Human
apoc1 tumor Frequently overexpressed genes (tumor/normal ratio > 2) were COL1A1 (percentage of cases with overexpression, 78.3%), CDH17 (73.9%), APOC1 (67.4%), COL1A2 (58.7%), YF13H12 (52.2%), CEACAM6 (50.0%), APOE (50.0%), REGIV (47.8%), S100A11 (41.3%), and FUS (41 15059891 Human
apoc1 hyperplasia Histopathological analysis of high expressor APOC1 transgenic mice revealed a disorder of the skin consisting of epidermal hyperplasia and hyperkeratosis, and atrophic sebaceous glands lacking sebum. 9421476 Human
apoc-i liposarcoma Synthesis and secretion of apoC-I and apoE during maturation of human SW872 liposarcoma cells. 15514255 Human
apoc-i liposarcoma The aim of the present study, therefore, was to investigate the effect of different tissue culture conditions on the synthesis and secretion of apoC-I and apoE in human SW872 liposarcoma cells. 15514255 Human
apoc-i human hepatoma In the present study, we have carried out experiments with human hepatoma (HepG2) cells, in order to determine the effect of different tissue culture conditions on cellular lipid levels and on the production of apoC-I (and apoE) at the protein and mRNA le 15694932 Human

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