IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene VASP Ensembl ENSG00000125753 Chromosome 19 Start 50702528 End 50722076
Description Vasodilator-stimulated phosphoprotein (VASP) [Source:UniProtKB/Swiss-Prot;Acc:P50552]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 12652
     Entrez Gene : 7408
     UCSC : uc002pcg.2
     GeneCards : 12652
     RefSeq : NM_003370
     CCDS : CCDS33051.1
     Uniprot : P50552
     Interpro : P50552
     OMIM : 601703
     GeneTests : VASP
     CGAP : VASP
     PMID : 8812448

< Top >


Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  39105_at  -0.69  3.00e-5  1.39e-4  -1.25  1.14e-7  8.67e-7
 HG_U133A  202205_at  -0.17  1.95e-2  2.91e-2  1.03  8.29e-28  1.35e-27
 HG_U133_Plus2  202205_at  0.40  5.20e-4  1.43e-3  0.53  1.87e-4  4.02e-4
 Stanford  7561  -0.14  4.67e-1  6.55e-1  -0.57  5.20e-2  1.75e-1
 Agilent_HS_21.6K  3730  -0.08  3.23e-1  5.12e-1  -0.15  3.66e-2  9.79e-2

< Top >


Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  202205_at  0.29  2.76e-1  8.65e-1  -0.20  1.04e-1  1.00e+0

< Top >


Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 39105_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 202205_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 202205_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 7561    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 3730    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

< Top >


Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
vasp colon cancer We found that VASP was phosphorylated after treating SW480 colon cancer cells with exisulind, CP461, or CP248. 12492113 Human
vasp glioma We quantitatively determined the amounts of laminin, fibronectin, vitronectin, and thrombospondin secreted by these glioma cell lines in vitro, as well as the amount of each of the eight beta integrin subunits and the adhesion complex-related molecules, i 11746774 Human
vasp sacrococcygeal teratoma METHODS: Between 1995 and 1998, 5 patients (two with prune belly syndrome, one with a cloacal anomaly, one with urethral stenosis, and one with a sacrococcygeal teratoma) underwent VASP using a double-basket catheter. 10654907 Human
vasp cancer Our results implicate VASP in tumorigenesis and/or cancer progression. 10207093 Human
vasodilator-stimulated phosphoprotein hyperplasia Megakaryocyte hyperplasia and enhanced agonist-induced platelet activation in vasodilator-stimulated phosphoprotein knockout mice. 10393958 Human
vasp tumour Understanding the role of VASP and other proteins in cell and bacterial motility is likely to lead to development of new therapeutic strategies for diseases including atherosclerosis and tumour growth, and for limiting the spread of intracellular pathogen 9611773 Human
vasp uterine leiomyosarcoma Western blot and immunofluorescence analysis detected VASP in human heart, femoral artery and a uterine leiomyosarcoma. 8922250 Human

< Top >


Download all image files.
Save all PNG files.    Save all PDF files.    Save all PS files.