IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene OPA3 Ensembl ENSG00000125741 Chromosome 19 Start 50722867 End 50779962
Description Optic atrophy 3 protein [Source:UniProtKB/Swiss-Prot;Acc:Q9H6K4]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 8142
     Entrez Gene : 80207
     UCSC : uc002pcj.3
     GeneCards : 8142
     RefSeq : NM_001017989
     CCDS : CCDS12668.1
     Uniprot : Q9H6K4
     Interpro : Q9H6K4
     OMIM : 606580
     GeneTests : OPA3
     CGAP : OPA3
     PMID : 9097959

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  206357_at  1.42  4.44e-23  4.33e-22  2.69  4.80e-38  9.03e-38
 HG_U133_Plus2  206357_at  -0.18  2.02e-1  2.78e-1  -0.43  1.70e-2  2.66e-2
 HG_U133_Plus2  229624_at  -0.06  5.44e-1  6.28e-1  0.30  7.41e-4  1.46e-3
 HG_U133_Plus2  238630_at  -0.51  1.57e-3  3.90e-3  -0.78  9.49e-5  2.12e-4
 Agilent_HS_21.6K  12235  -0.01  8.96e-1  9.43e-1  0.01  8.56e-1  9.12e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  206357_at  0.66  2.51e-1  8.53e-1  -0.15  6.34e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U133A - 206357_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 206357_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 229624_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 238630_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 12235    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
opa3 tumor DD-PCR with the arbitrary primer OPA3 showed that one cDNA band was highly expressed in normal tissues, but disappeared or substantially decreased in tumor counterparts. 15040889 Human

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