IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene GIPR Ensembl ENSG00000010310 Chromosome 19 Start 50863342 End 50877544
Description Gastric inhibitory polypeptide receptor Precursor (GIP-R)(Glucose-dependent insulinotropic polypeptide receptor) [Source:UniProtKB/Swiss-Prot;Acc:P48546]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 4271
     Entrez Gene : 2696
     UCSC : uc002pcu.1
     GeneCards : 4271
     RefSeq : NM_000164
     CCDS : CCDS12671.1
     Uniprot : P48546
     Interpro : P48546
     OMIM : 137241
     GeneTests : GIPR
     CGAP : GIPR
     PMID : 7490109

< Top >


Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  35589_at  0.23  1.14e-1  1.83e-1  0.03  8.73e-1  9.10e-1
 HG_U95  35590_s_at  0.53  4.55e-9  4.95e-8  0.37  3.48e-3  9.19e-3
 HG_U133A  208105_at  -0.32  1.45e-2  2.21e-2  2.85  1.48e-54  3.63e-54
 HG_U133_Plus2  208105_at  -0.28  8.02e-2  1.27e-1  -0.63  2.54e-3  4.58e-3
 Agilent_HS_21.6K  15876  0.07  2.70e-1  4.55e-1  0.07  1.78e-1  3.16e-1

< Top >


Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  208105_at  -0.82  6.59e-2  7.28e-1  0.13  5.95e-1  1.00e+0

< Top >


Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 35589_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U95 - 35590_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 208105_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 208105_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 15876    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

< Top >


Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
gastric inhibitory polypeptide receptor macronodular adrenal hyperplasia The ectopic expression of the gastric inhibitory polypeptide receptor is frequent in adrenocorticotropin-independent bilateral macronodular adrenal hyperplasia, but rare in unilateral tumors. 11994328 Human
gastric inhibitory polypeptide receptor tumors The ectopic expression of the gastric inhibitory polypeptide receptor is frequent in adrenocorticotropin-independent bilateral macronodular adrenal hyperplasia, but rare in unilateral tumors. 11994328 Human
gastric inhibitory polypeptide receptor macronodular hyperplasia Control of cortisol secretion by the abnormal expression of the gastric inhibitory polypeptide receptor (GIP-R) have been observed in some rare cases of ACTH-independent, food-dependent Cushing's syndrome (FD-ACS) due to adrenal adenoma (AA) or bilat 11994328 Human
gastric inhibitory polypeptide receptor adrenal adenoma (aa) Control of cortisol secretion by the abnormal expression of the gastric inhibitory polypeptide receptor (GIP-R) have been observed in some rare cases of ACTH-independent, food-dependent Cushing's syndrome (FD-ACS) due to adrenal adenoma (AA) or bilat 11994328 Human
gipr hyperplasia We conclude that GIP-dependent nodular hyperplasia can progress in an asynchronous manner and that GIPR overexpression is an early event in this syndrome. 10443649 Human
gipr hyperplasias The expression of GIPR was studied by RT-PCR in human adrenal tissues from two patients with GIP-dependent Cushing's syndrome (adenoma, bilateral hyperplasia), five fetal or adult controls, one patient with Cushing's disease, and four patients w 9709947 Human
gipr cortisol-secreting adenomas The expression of GIPR was studied by RT-PCR in human adrenal tissues from two patients with GIP-dependent Cushing's syndrome (adenoma, bilateral hyperplasia), five fetal or adult controls, one patient with Cushing's disease, and four patients w 9709947 Human
gipr adenoma The expression of GIPR was studied by RT-PCR in human adrenal tissues from two patients with GIP-dependent Cushing's syndrome (adenoma, bilateral hyperplasia), five fetal or adult controls, one patient with Cushing's disease, and four patients w 9709947 Human
gipr hyperplasia The expression of GIPR was studied by RT-PCR in human adrenal tissues from two patients with GIP-dependent Cushing's syndrome (adenoma, bilateral hyperplasia), five fetal or adult controls, one patient with Cushing's disease, and four patients w 9709947 Human
gipr macronodular hyperplasia Hybridization of the RT-PCR-amplified ribonucleic acids with the human GIPR complementary DNA showed an overexpression of GIPR in the adrenals of the two GIP-dependent Cushing's syndrome patients compared to that in normal adrenal tissues (2-3 orders 9709947 Human
gipr adrenal adenomas Hybridization of the RT-PCR-amplified ribonucleic acids with the human GIPR complementary DNA showed an overexpression of GIPR in the adrenals of the two GIP-dependent Cushing's syndrome patients compared to that in normal adrenal tissues (2-3 orders 9709947 Human
gipr hyperplastic RESULTS: RT-PCR revealed GIPR expression in all hyperplastic adrenals studied. 15705925 Human

< Top >


Download all image files.
Save all PNG files.    Save all PDF files.    Save all PS files.