IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene AP2S1 Ensembl ENSG00000042753 Chromosome 19 Start 52033263 End 52046043
Description AP-2 complex subunit sigma-1 (Adapter-related protein complex 2 sigma-1 subunit)(Sigma2-adaptin)(Plasma membrane adaptor AP-2 17 kDa protein)(HA2 17 kDa subunit)(Clathrin assembly protein 2 small chain)(Clathrin coat assembly protein AP17)(Clathrin coat-associated protein AP17) [Source:UniProtKB/Swiss-Prot;Acc:P53680]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 565
     Entrez Gene : 1175
     UCSC : uc002pft.1
     GeneCards : 565
     RefSeq : NM_004069
     CCDS : CCDS12693.1
     Uniprot : P53680
     Interpro : P53680
     OMIM : 602242
     GeneTests : AP2S1
     CGAP : AP2S1
     PMID : 9040778

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  39347_at  0.15  8.44e-2  1.43e-1  0.56  2.61e-6  1.49e-5
 HG_U133A  202120_x_at  0.04  5.23e-1  5.76e-1  -0.10  2.92e-1  3.02e-1
 HG_U133A  208074_s_at  0.64  9.42e-18  6.26e-17  -2.45  1.68e-32  2.92e-32
 HG_U133A  211047_x_at  0.40  9.02e-9  2.86e-8  -5.54  5.28e-92  2.89e-91
 HG_U133_Plus2  202120_x_at  0.16  4.71e-2  8.00e-2  0.72  7.70e-12  4.22e-11
 HG_U133_Plus2  208074_s_at  0.49  1.47e-7  7.59e-7  0.86  1.74e-17  1.81e-16
 HG_U133_Plus2  211047_x_at  0.40  1.82e-7  9.28e-7  0.83  1.16e-16  1.10e-15
 Stanford  10855  0.38  1.73e-1  3.55e-1  0.63  2.76e-2  1.16e-1
 Agilent_HS_21.6K  10024  -0.09  1.40e-1  2.95e-1  0.04  4.88e-1  6.38e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  202120_x_at  -0.07  7.20e-1  9.72e-1  -0.00  9.75e-1  1.00e+0
 HG_U133A  208074_s_at  0.06  8.17e-1  9.84e-1  -0.07  6.59e-1  1.00e+0
 HG_U133A  211047_x_at  0.05  8.03e-1  9.83e-1  0.00  9.92e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 39347_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 202120_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 208074_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 211047_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 202120_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 208074_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 211047_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 10855    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 10024    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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