IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene NAPA Ensembl ENSG00000105402 Chromosome 19 Start 52682703 End 52710309
Description Alpha-soluble NSF attachment protein (SNAP-alpha)(N-ethylmaleimide-sensitive factor attachment protein alpha) [Source:UniProtKB/Swiss-Prot;Acc:P54920]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 7641
     Entrez Gene : 8775
     UCSC : uc002pha.1
     GeneCards : 7641
     RefSeq : NM_003827
     CCDS : CCDS12702.1
     Uniprot : P54920
     Interpro : P54920
     OMIM : 603215
     GeneTests : NAPA
     CGAP : NAPA
     PMID : 9269766

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  36977_at  -0.29  4.18e-4  1.46e-3  -0.30  2.29e-4  8.34e-4
 HG_U133A  206491_s_at  -0.31  2.27e-6  5.64e-6  -2.73  9.40e-70  3.04e-69
 HG_U133A  208751_at  -0.30  1.51e-8  4.67e-8  -5.04  3.31e-104  2.52e-103
 HG_U133_Plus2  206491_s_at  0.06  5.05e-1  5.92e-1  0.23  2.05e-2  3.15e-2
 HG_U133_Plus2  208751_at  -0.18  4.07e-2  7.03e-2  0.02  8.15e-1  8.46e-1
 HG_U133_Plus2  239362_at  -0.22  2.01e-1  2.78e-1  -0.33  8.26e-2  1.13e-1
 Stanford  11240  0.30  4.70e-1  6.57e-1  0.43  2.44e-1  4.79e-1
 Stanford  17660  -0.57  2.30e-2  1.10e-1  -0.95  2.39e-3  2.54e-2
 Agilent_HS_21.6K  10296  -0.19  2.02e-4  2.13e-3  -0.20  1.94e-6  2.75e-5

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  206491_s_at  0.22  3.09e-1  8.78e-1  -0.07  5.14e-1  1.00e+0
 HG_U133A  208751_at  0.12  5.78e-1  9.48e-1  0.03  8.30e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 36977_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 206491_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 208751_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 206491_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 208751_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 239362_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 11240    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 17660    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 10296    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
alpha-snap human neuroblastoma Western blot analysis showed that the human neuroblastoma SH-SY5Y expresses the proteins synaptotagmin l, synaptobrevin, synapsin-l, rab3a, syntaxin, SNAP-25, NSF, alpha-SNAP, and munc-18, which have been implicated in the movement, docking, and fusion of 9084425 Human
alpha snap cancer A ubiquitous membrane fusion protein alpha SNAP: a potential therapeutic target for cancer, diabetes and neurological disorders? 16981829 Human

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