IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene DBP Ensembl ENSG00000105516 Chromosome 19 Start 53825659 End 53832435
Description D site-binding protein (Albumin D box-binding protein)(Albumin D-element-binding protein)(TAXREB302) [Source:UniProtKB/Swiss-Prot;Acc:Q10586]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 2697
     Entrez Gene : 1628
     UCSC : uc002pjx.3
     GeneCards : 2697
     RefSeq : NM_001352
     CCDS : CCDS12728.1
     Uniprot : Q10586
     Interpro : Q10586
     OMIM : 124097
     GeneTests : DBP
     CGAP : DBP
     PMID : 1535333

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  40274_at  -0.12  3.77e-1  4.83e-1  0.01  9.60e-1  9.73e-1
 HG_U133A  209782_s_at  0.06  5.44e-1  5.95e-1  0.69  7.99e-10  9.99e-10
 HG_U133A  209783_at  -0.42  1.09e-3  1.98e-3  1.63  3.29e-39  6.30e-39
 HG_U133_Plus2  209782_s_at  0.63  3.77e-10  2.79e-9  1.06  4.77e-15  3.76e-14
 HG_U133_Plus2  209783_at  0.46  4.18e-3  9.39e-3  0.77  2.44e-5  5.93e-5
 Agilent_HS_21.6K  14578  0.10  5.02e-1  6.75e-1  0.12  3.10e-1  4.68e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  209782_s_at  -0.02  9.45e-1  9.97e-1  0.08  7.03e-1  1.00e+0
 HG_U133A  209783_at  -0.05  9.16e-1  9.95e-1  -0.15  6.44e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 40274_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 209782_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 209783_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 209782_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 209783_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 14578    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
dbp hepatoma Using transient transfection assays in HepG2 hepatoma cells, we demonstrated the ability of HLF alone and in synergistic combination with the D-box binding protein (DBP), another proline and acidic-rich (PAR) protein family member, to transactivate these 10073576 Human
dbp gliomas Microarray analysis identified 8 genes from these regions (MGC4399, SRM, ICMT, RPL18, FTL, ZIN, FLJ10781 and DBP), which all showed significantly lower expression in 1p/19q-deleted gliomas when compared to gliomas without 1p/19q losses. 16550607 Human

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