IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene NUCB1 Ensembl ENSG00000104805 Chromosome 19 Start 54095119 End 54118340
Description Nucleobindin-1 Precursor (CALNUC) [Source:UniProtKB/Swiss-Prot;Acc:Q02818]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 8043
     Entrez Gene : 4924
     UCSC : uc002plc.2
     GeneCards : 8043
     RefSeq : NM_006184
     CCDS : CCDS12740.1
     Uniprot : Q02818
     Interpro : Q02818
     OMIM : 601323
     GeneTests : NUCB1
     CGAP : NUCB1
     PMID : 8661046

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  40817_at  -0.54  2.91e-7  2.16e-6  -1.01  3.14e-12  5.73e-11
 HG_U133A  200646_s_at  0.29  1.70e-3  3.00e-3  -0.17  6.87e-2  7.28e-2
 HG_U133A  200649_at  -0.14  3.10e-2  4.48e-2  -2.65  4.96e-30  8.33e-30
 HG_U133_Plus2  200646_s_at  -0.05  6.50e-1  7.22e-1  -0.10  4.74e-1  5.35e-1
 HG_U133_Plus2  200649_at  -0.01  8.97e-1  9.24e-1  0.16  2.61e-1  3.17e-1
 Stanford  12146  -0.78  7.68e-2  2.08e-1  -0.60  5.17e-2  1.75e-1
 Agilent_HS_21.6K  5547  -0.19  2.47e-3  1.58e-2  -0.23  1.75e-5  1.82e-4

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  200646_s_at  -0.03  9.19e-1  9.95e-1  -0.34  6.02e-2  1.00e+0
 HG_U133A  200649_at  0.05  7.85e-1  9.81e-1  -0.02  9.16e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 40817_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 200646_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 200649_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 200646_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 200649_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 12146    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 5547    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
nuc gastric adenocarcinomas A total of 100 gastric adenocarcinomas, comprising 50 cases with lymph node metastasis and 50 cases without lymph node metastasis, were examined for immunohistochemical reactivity with the monoclonal antibody to urokinase-type plasminogen activator (u-PA) 7866567 Human
nuc lymph-node metastasis A total of 100 gastric adenocarcinomas, comprising 50 cases with lymph node metastasis and 50 cases without lymph node metastasis, were examined for immunohistochemical reactivity with the monoclonal antibody to urokinase-type plasminogen activator (u-PA) 7866567 Human
nuc tumors In tumors with lymph node metastasis, 41 (82%) were positive for u-PA and 28 (56%) were positive for Nuc. 7866567 Human
nuc lymph-node metastasis In tumors with lymph node metastasis, 41 (82%) were positive for u-PA and 28 (56%) were positive for Nuc. 7866567 Human
nuc tumors In tumors without lymph node metastasis, 26 (52%) were positive for u-PA and five (10%) were positive for Nuc. 7866567 Human
nuc lymph-node metastasis In tumors without lymph node metastasis, 26 (52%) were positive for u-PA and five (10%) were positive for Nuc. 7866567 Human
nuc tumors The percentage of cases positive for u-PA or Nuc was significantly higher in tumors with lymph node metastasis than that in tumors without lymph node metastasis (P < 0.01). 7866567 Human
nuc lymph-node metastasis The percentage of cases positive for u-PA or Nuc was significantly higher in tumors with lymph node metastasis than that in tumors without lymph node metastasis (P < 0.01). 7866567 Human
nuc tumor These results suggest that immunohistochemical examination for the expression of u-PA and Nuc in tumor cells may help evaluate the potential of adenocarcinomas of the stomach for lymph node metastasis. 7866567 Human
nuc adenocarcinomas These results suggest that immunohistochemical examination for the expression of u-PA and Nuc in tumor cells may help evaluate the potential of adenocarcinomas of the stomach for lymph node metastasis. 7866567 Human
nuc lymph-node metastasis These results suggest that immunohistochemical examination for the expression of u-PA and Nuc in tumor cells may help evaluate the potential of adenocarcinomas of the stomach for lymph node metastasis. 7866567 Human
nuc adenocarcinomas of the stomach These results suggest that immunohistochemical examination for the expression of u-PA and Nuc in tumor cells may help evaluate the potential of adenocarcinomas of the stomach for lymph node metastasis. 7866567 Human

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