IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene FTL Ensembl ENSG00000087086 Chromosome 19 Start 54160378 End 54161947
Description Ferritin light chain (Ferritin L subunit) [Source:UniProtKB/Swiss-Prot;Acc:P02792]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 3999
     Entrez Gene : 2512
     UCSC : uc002plo.2
     GeneCards : 3999
     RefSeq : NM_000146
     CCDS : CCDS33070.1
     Uniprot : P02792
     Interpro : P02792
     OMIM : 134790
     GeneTests : FTL
     CGAP : FTL
     PMID : 3000916

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  35083_at  -0.20  1.82e-3  5.33e-3  -0.50  6.78e-6  3.55e-5
 HG_U133A  212788_x_at  -0.23  4.05e-10  1.46e-9  -5.70  3.44e-165  2.23e-163
 HG_U133A  213187_x_at  -0.28  2.13e-7  5.88e-7  -5.05  5.01e-152  1.82e-150
 HG_U133_Plus2  212788_x_at  -0.11  2.48e-4  7.29e-4  -0.09  3.57e-2  5.26e-2
 HG_U133_Plus2  213187_x_at  -0.24  7.72e-5  2.50e-4  -0.33  4.82e-6  1.29e-5
 Stanford  6404  -2.72  3.28e-6  3.17e-4  -2.57  4.32e-9  2.61e-6
 Stanford  8030  0.87  7.33e-3  5.26e-2  1.63  4.64e-5  1.56e-3
 Stanford  9227  0.62  7.74e-3  5.46e-2  0.67  3.56e-2  1.34e-1
 Stanford  11970  0.78  9.01e-3  6.03e-2  1.09  1.21e-2  7.86e-2
 Stanford  16116  0.54  8.62e-2  2.24e-1  1.11  1.20e-2  7.82e-2
 Agilent_HS_21.6K  4632  -0.20  4.96e-2  1.45e-1  -0.19  7.09e-2  1.60e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  212788_x_at  0.08  6.02e-1  9.53e-1  -0.10  3.30e-1  1.00e+0
 HG_U133A  213187_x_at  0.32  1.32e-1  7.95e-1  -0.26  7.38e-2  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 35083_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 212788_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 213187_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 212788_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 213187_x_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 6404    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 8030    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 9227    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 11970    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Stanford - 16116    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 4632    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
ftl mesothelioma Among them, the expression levels of eight genes, namely BF, FTL, IGFBP7, RARRES1, RARRES2, RBP1, SAT, and TXN according to HUGO nomenclature, were increased, whereas six: ALOX5AP, CLNS1A, EIF4A2, ELK3, REQ and SYPL, were found to be underexpressed in mes 14987796 Human
the ftl gene pd In this study, 253 patients with a clinical diagnosis of idiopathic PD were screened for the insertion in the FTL gene by polymerase chain reaction-restriction fragment length polymorphism method. 12459518 Human
the ftl gene pd The results showed that none of them had the mutation, indicating that genetic defects in the FTL gene are unlikely to be a common cause of typical PD, at least in a North America population. 12459518 Human

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