IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene PRMT1 Ensembl ENSG00000126457 Chromosome 19 Start 54872350 End 54883516
Description Protein arginine N-methyltransferase 1 (EC 2.1.1.-)(Interferon receptor 1-bound protein 4) [Source:UniProtKB/Swiss-Prot;Acc:Q99873]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 5187
     Entrez Gene : 3276
     UCSC : uc010enf.1
     GeneCards : 5187
     RefSeq : NM_001536
     CCDS : CCDS12778.1
     Uniprot : Q9NZ06
     Interpro : Q9NZ06
     OMIM : 602950
     GeneTests : PRMT1
     CGAP : PRMT1
     PMID : 9545638

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  32825_at  -0.09  2.39e-1  3.38e-1  0.33  8.44e-4  2.68e-3
 HG_U133A  206445_s_at  0.36  1.07e-8  3.38e-8  -2.95  8.69e-76  3.19e-75
 HG_U133_Plus2  1565016_at  0.42  3.10e-2  5.54e-2  0.84  1.60e-4  3.47e-4
 HG_U133_Plus2  206445_s_at  0.51  1.34e-6  5.91e-6  1.07  9.05e-21  1.37e-19

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  206445_s_at  0.33  4.99e-2  7.08e-1  0.14  3.41e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 32825_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 206445_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 1565016_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 206445_s_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
prmt1 breast cancer Although PRMT1 was not found to be hormonally regulated by steroid hormones in breast cancer cells, our results suggest that two variants of PRMT1 are down regulated in breast cancer. 11097842 Human

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