IGDB.NSCLC Gene View
 
Gene Information        (help)
Gene KCNC3 Ensembl ENSG00000131398 Chromosome 19 Start 55507006 End 55524446
Description Potassium voltage-gated channel subfamily C member 3 (Voltage-gated potassium channel subunit Kv3.3)(KSHIIID) [Source:UniProtKB/Swiss-Prot;Acc:Q14003]
GENE RESOURCES :NUCLEOTIDE SEQUENCES :PROTEIN RESOURCES :CLINICAL RESOURCES :REFERENCES :
     HGNC : 6235
     Entrez Gene : 3748
     UCSC : uc002pru.1
     GeneCards : 6235
     RefSeq : NM_004977
     CCDS : CCDS12793.1
     Uniprot : Q14003
     Interpro : Q14003
     OMIM : 176264
     GeneTests : KCNC3
     CGAP : KCNC3
     PMID : 1740329

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Microarray Gene Expression Fold Change Result        (help)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background : these probesets might have mapping problems. ref 1, ref 2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U95  31341_at  0.51  1.51e-3  4.51e-3  0.69  1.05e-2  2.42e-2
 HG_U133A  207600_at  -0.63  2.49e-10  9.16e-10  -3.36  3.61e-109  3.15e-108
 HG_U133_Plus2  207600_at  0.45  6.63e-3  1.42e-2  0.54  4.00e-3  6.99e-3
 HG_U133_Plus2  230531_at  -0.33  1.02e-1  1.55e-1  0.03  9.08e-1  9.26e-1
 HG_U133_Plus2  243893_at  0.53  1.46e-3  3.66e-3  0.09  5.20e-1  5.78e-1
 Agilent_HS_21.6K  9550  -0.02  5.05e-1  6.78e-1  -0.02  3.70e-1  5.31e-1

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Adjuvant Cisplatin/vinorelbine Treatment vs Observation Result        (help) (Pubmed)
( red: up-regulation / green : down-regulation when p value < 0.01)
( gray background color : the mapping problems of probeset. ref_1, ref_2)
Chip Type Probeset Adenocarcinoma Squamous Cell Carcinoma
Fold Change p value q value Fold Change p value q value
 HG_U133A  207600_at  0.01  9.62e-1  9.98e-1  -0.21  3.03e-1  1.00e+0

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Microarray Sample Data        (help)
( The log2 value of tumor samples )
(Average : Average log2 value from Normal Samples.)
        HG_U95 - 31341_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133A - 207600_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 207600_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 230531_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        HG_U133_Plus2 - 243893_at    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

        Agilent_HS_21.6K - 9550    (back)       Save as a PNG file. Save as a PDF file. Save as a PS file.
Gene expression figure

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Cancer Gene Index        (help)

If 0 entry was found, please remove the search key "lung cancer".
Keyword DiseaseData Statement PubMed Organism
kv3.3 ascites hepatoma Expression of both delayed rectifier (Kv1.1, Kv1.2, Kv1.3, Kv1.5, Kv1.6, Kv2.1, Kv3.1, Kv4.2) and A-type potassium channels (Kv1.4, Kv3.3, Kv3.4) was greatly down-regulated in brain from animals bearing a Yoshida AH-130 ascites hepatoma. 12586336 Rat

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